Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers | Nature Biotechnology | 2015 | 1.1K |
3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures | Advanced Materials | 2015 | 577 |
Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements | Nature Methods | 2015 | 554 |
Randomized Comparison of Percutaneous Repair and Surgery for Mitral Regurgitation: 5-Year Results of EVEREST II | Journal of the American College of Cardiology | 2015 | 442 |
A light-inducible CRISPR-Cas9 system for control of endogenous gene activation | Nature Chemical Biology | 2015 | 437 |
HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers | Science | 2015 | 394 |
Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients | Nature | 2015 | 333 |
Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy | Nature Communications | 2015 | 307 |
Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes | Cell | 2015 | 251 |
Benefits of a novel percutaneous ventricular assist device for right heart failure: The prospective RECOVER RIGHT study of the Impella RP device | Journal of Heart and Lung Transplantation | 2015 | 226 |
The Patient Acceptable Symptomatic State for the Modified Harris Hip Score and Hip Outcome Score Among Patients Undergoing Surgical Treatment for Femoroacetabular Impingement | American Journal of Sports Medicine | 2015 | 202 |
Combined Mechanical and Oral Antibiotic Bowel Preparation Reduces Incisional Surgical Site Infection and Anastomotic Leak Rates After Elective Colorectal Resection: An Analysis of Colectomy-Targeted ACS NSQIP | Annals of Surgery | 2015 | 198 |
Management of the Potential Organ Donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus Statement | Critical Care Medicine | 2015 | 197 |
Designing a broad-spectrum integrative approach for cancer prevention and treatment | Seminars in Cancer Biology | 2015 | 179 |
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead | Carcinogenesis | 2015 | 176 |
Minimally Invasive Versus Open Pancreaticoduodenectomy for Cancer: Practice Patterns and Short-term Outcomes Among 7061 Patients | Annals of Surgery | 2015 | 170 |
American Society for Metabolic and Bariatric Surgery estimation of bariatric surgery procedures in the United States, 2011-2014 | Surgery for Obesity and Related Diseases | 2015 | 145 |
Association between surgical indications, operative risk, and clinical outcome in infective endocarditis: a prospective study from the International Collaboration on Endocarditis | Circulation | 2015 | 144 |
Aligned multilayered electrospun scaffolds for rotator cuff tendon tissue engineering | Acta Biomaterialia | 2015 | 134 |
Adjuvant radioactive iodine therapy is associated with improved survival for patients with intermediate-risk papillary thyroid cancer | Journal of Clinical Endocrinology and Metabolism | 2015 | 128 |
A national snapshot of satisfaction with breast cancer procedures | Annals of Surgical Oncology | 2015 | 120 |
Diagnostic accuracy of clinical tests for the diagnosis of hip femoroacetabular impingement/labral tear: a systematic review with meta-analysis | British Journal of Sports Medicine | 2015 | 120 |
Increased proportion of FoxP3+ regulatory T cells in tumor infiltrating lymphocytes is associated with tumor recurrence and reduced survival in patients with glioblastoma | Cancer Immunology, Immunotherapy | 2015 | 119 |
Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site | PLoS Pathogens | 2015 | 116 |
Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy | Cancer Immunology Research | 2015 | 116 |