| # | Title | Journal | Year | Citations |
|---|
| 1 | A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance | Cell Metabolism | 2009 | 2,597 |
| 2 | Improving clinical practice using clinical decision support systems: a systematic review of trials to identify features critical to success | BMJ: British Medical Journal | 2005 | 1,998 |
| 3 | Regression modelling strategies for improved prognostic prediction | Statistics in Medicine | 1984 | 1,486 |
| 4 | The Impact of Surgical-Site Infections in the 1990s: Attributable Mortality, Excess Length of Hospitalization, And Extra Costs | Infection Control and Hospital Epidemiology | 1999 | 1,448 |
| 5 | A brief self-administered questionnaire to determine functional capacity (The Duke Activity Status Index) | American Journal of Cardiology | 1989 | 1,422 |
| 6 | Primary Care: Is There Enough Time for Prevention? | American Journal of Public Health | 2003 | 1,328 |
| 7 | General Performance on a Numeracy Scale among Highly Educated Samples | Medical Decision Making | 2001 | 1,233 |
| 8 | The Duke???UNC Functional Social Support Questionnaire | Medical Care | 1988 | 1,052 |
| 9 | Predictors of 30-Day Mortality in the Era of Reperfusion for Acute Myocardial Infarction | Circulation | 1995 | 901 |
| 10 | Depression, Disability Days, and Days Lost From Work in a Prospective Epidemiologic Survey | JAMA - Journal of the American Medical Association | 1990 | 861 |
| 11 | Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case–control studies | Lancet Oncology, The | 2012 | 753 |
| 12 | A systematic review of recommendations and guidelines for the management of osteoarthritis: The Chronic Osteoarthritis Management Initiative of the U.S. Bone and Joint Initiative | Seminars in Arthritis and Rheumatism | 2014 | 629 |
| 13 | Is There Time for Management of Patients With Chronic Diseases in Primary Care? | Annals of Family Medicine | 2005 | 606 |
| 14 | Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer | Nature Genetics | 2013 | 493 |
| 15 | Factors Predictive of Survival Among 337 Patients With Mesothelioma Treated Between 1984 and 1994 by the Cancer and Leukemia Group B | Chest | 1998 | 474 |
| 16 | Current health behaviors and readiness to pursue life-style changes among men and women diagnosed with early stage prostate and breast carcinomas | Chest | 2000 | 451 |
| 17 | Effect of age and gender on the activity of human hepatic CYP3A | Biochemical Pharmacology | 1992 | 393 |
| 18 | GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer | Nature Genetics | 2013 | 326 |
| 19 | Diffusion tensor imaging of adult age differences in cerebral white matter: relation to response time | NeuroImage | 2004 | 322 |
| 20 | A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24 | Nature Genetics | 2010 | 321 |
| 21 | Understanding and Using DICOM, the Data Interchange Standard for Biomedical Imaging | Journal of the American Medical Informatics Association: JAMIA | 1997 | 311 |
| 22 | The Duke Health Profile | Medical Care | 1990 | 309 |
| 23 | Epithelial Ovarian Cancer Risk Among Women With Polycystic Ovary Syndrome | Obstetrics and Gynecology | 1996 | 287 |
| 24 | The contribution of sensory experience to the maturation of orientation selectivity in ferret visual cortex | Nature | 2001 | 267 |
| 25 | Depression, disability days, and days lost from work in a prospective epidemiologic survey | JAMA - Journal of the American Medical Association | 1990 | 266 |
| 26 | Computerized Decision Support Based on a Clinical Practice Guideline Improves Compliance with Care Standards | American Journal of Medicine | 1997 | 265 |
| 27 | Newborns of obese parents have altered DNA methylation patterns at imprinted genes | International Journal of Obesity | 2015 | 265 |
| 28 | The Accuracy of Medicare Claims as an Epidemiological Tool: The Case of Dementia Revisited | Journal of Alzheimer's Disease | 2009 | 253 |
| 29 | Common variants at 19p13 are associated with susceptibility to ovarian cancer | Nature Genetics | 2010 | 235 |
| 30 | Incremental diagnostic yield of loop electrocardiographic recorders in unexplained syncope | American Journal of Cardiology | 1990 | 230 |
| 31 | Prognostic implications of angiographically normal and insignificantly narrowed coronary arteries | American Journal of Cardiology | 1986 | 229 |
| 32 | Obesity and Workers' Compensation | Archives of Internal Medicine | 2007 | 228 |
| 33 | Methylation variation atIGF2differentially methylated regions and maternal folic acid use before and during pregnancy | Epigenetics | 2011 | 225 |
| 34 | Identification of six new susceptibility loci for invasive epithelial ovarian cancer | Nature Genetics | 2015 | 221 |
| 35 | Teachable Moments for Promoting Smoking Cessation: The Context of Cancer Care and Survivorship | Cancer Control | 2003 | 217 |
| 36 | Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium | Human Molecular Genetics | 2017 | 211 |
| 37 | Value of exercise treadmill testing in women | Journal of the American College of Cardiology | 1998 | 205 |
| 38 | Outcomes of Coronary Artery Bypass Graft Surgery in 24 461 Patients Aged 80 Years or Older | Circulation | 1995 | 205 |
| 39 | Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke | Gene | 2012 | 201 |
| 40 | Obesity and Sexual Quality of Life | Obesity | 2006 | 193 |
| 41 | History of Foot Ulcer Increases Mortality Among Individuals With Diabetes | Diabetes Care | 2009 | 190 |
| 42 | Prognostic value of radionuclide angiography in medically treated patients with coronary artery disease. A comparison with clinical and catheterization variables. | Circulation | 1990 | 188 |
| 43 | Successful immune tolerance induction to enzyme replacement therapy in CRIM-negative infantile Pompe disease | Genetics in Medicine | 2012 | 183 |
| 44 | Exercise to Improve Spinal Flexibility and Function for People with Parkinson's Disease: A Randomized, Controlled Trial | Journal of the American Geriatrics Society | 1998 | 172 |
| 45 | Parent-child relationship of directly measured physical activity | International Journal of Behavioral Nutrition and Physical Activity | 2011 | 170 |
| 46 | Active Mothers Postpartum | American Journal of Preventive Medicine | 2009 | 165 |
| 47 | Effect of Hysterectomy With Ovarian Preservation on Ovarian Function | Obstetrics and Gynecology | 2011 | 165 |
| 48 | Economic Assessment of Low-Molecular-Weight Heparin (Enoxaparin) Versus Unfractionated Heparin in Acute Coronary Syndrome Patients | Circulation | 1998 | 163 |
| 49 | The emerging phenotype of long-term survivors with infantile Pompe disease | Genetics in Medicine | 2012 | 163 |
| 50 | Prognostic implications of ventricular arrhythmias during 24 hour ambulatory monitoring in patients undergoing cardiac catheterization for coronary artery disease | American Journal of Cardiology | 1982 | 162 |
