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exaly
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Department of Cancer Biology
›
top-articles
Department of Cancer Biology
102
(top 1%)
papers
5.1K
(top 1%)
citations
35
(top 1%)
h
-index
71
(top 1%)
g
-index
109
all documents
5.4K
doc citations
1.4K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine
Nucleic Acids Research
2010
389
2
Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib
Cancer Cell
2012
374
3
Genomic mapping of 5-hydroxymethylcytosine in the human brain
Nucleic Acids Research
2011
344
4
Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene,
RORA
, whose protein product is reduced in autistic brain
FASEB Journal
2010
320
5
NAMPT overexpression in prostate cancer and its contribution to tumor cell survival and stress response
Oncogene
2011
211
6
SIRT1 Activation by a c-MYC Oncogenic Network Promotes the Maintenance and Drug Resistance of Human FLT3-ITD Acute Myeloid Leukemia Stem Cells
Cell Stem Cell
2014
187
7
Epigenetic changes of DNA repair genes in cancer
Journal of Molecular Cell Biology
2011
168
8
Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis
Blood
2012
164
9
Mutational spectra of human cancer
Human Genetics
2009
160
10
5-hydroxymethylcytosine and its potential roles in development and cancer
Epigenetics and Chromatin
2013
157
11
CD30 Downregulation, MMAE Resistance, and
MDR1
Upregulation Are All Associated with Resistance to Brentuximab Vedotin
Molecular Cancer Therapeutics
2015
153
12
Identification of a 4-microRNA Signature for Clear Cell Renal Cell Carcinoma Metastasis and Prognosis
PLoS ONE
2012
153
13
MicroRNA profiling of clear cell renal cell carcinoma by whole‐genome small RNA deep sequencing of paired frozen and formalin‐fixed, paraffin‐embedded tissue specimens
Journal of Pathology
2010
147
14
Okazaki fragment maturation: nucleases take centre stage
Journal of Molecular Cell Biology
2011
143
15
Neural Stem Cell–Based Anticancer Gene Therapy: A First-in-Human Study in Recurrent High-Grade Glioma Patients
Clinical Cancer Research
2017
121
16
The emerging and diverse roles of sirtuins in cancer: a clinical perspective
OncoTargets and Therapy
2013
118
17
Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding
Nature Chemical Biology
2010
110
18
The Tumor Suppressor RASSF1A Prevents Dephosphorylation of the Mammalian STE20-like Kinases MST1 and MST2
Journal of Biological Chemistry
2011
99
19
SIRT1 deacetylase promotes acquisition of genetic mutations for drug resistance in CML cells
Oncogene
2013
95
20
Polyploid cells rewire DNA damage response networks to overcome replication stress-induced barriers for tumour progression
Nature Communications
2012
76
21
Cross-talk between ER and HER2 regulates c-MYC-mediated glutamine metabolism in aromatase inhibitor resistant breast cancer cells
Journal of Steroid Biochemistry and Molecular Biology
2015
71
22
Emerging Roles of SIRT1 in Cancer Drug Resistance
Genes and Cancer
2013
69
23
Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells
Journal of Clinical Investigation
2017
64
24
Environmental exposures and mutational patterns of cancer genomes
Genome Medicine
2010
58
25
An emerging trend of rapid increase of leukemia but not all cancers in the aging population in the United States
Scientific Reports
2019
58
26
DNA Repair in Human Pluripotent Stem Cells Is Distinct from That in Non-Pluripotent Human Cells
PLoS ONE
2012
52
27
Down-regulation of programmed cell death 4 (PDCD4) is associated with aromatase inhibitor resistance and a poor prognosis in estrogen receptor-positive breast cancer
Breast Cancer Research and Treatment
2015
52
28
BCR-ABL Gene Expression Is Required for Its Mutations in a Novel KCL-22 Cell Culture Model for Acquired Resistance of Chronic Myelogenous Leukemia
Journal of Biological Chemistry
2010
47
29
Aromatase deficiency in a Chinese adult man caused by novel compound heterozygous CYP19A1 mutations: Effects of estrogen replacement therapy on the bone, lipid, liver and glucose metabolism
Molecular and Cellular Endocrinology
2015
46
30
NADP+ is an endogenous PARP inhibitor in DNA damage response and tumor suppression
Nature Communications
2019
45
31
Loss of the Polycomb Mark from Bivalent Promoters Leads to Activation of Cancer-Promoting Genes in Colorectal Tumors
Cancer Research
2014
43
32
Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2
DNA Repair
2012
42
33
Evaluation of platelet indices as diagnostic biomarkers for colorectal cancer
Scientific Reports
2018
42
34
Epigenetic dysregulation by nickel through repressive chromatin domain disruption
Proceedings of the National Academy of Sciences of the United States of America
2014
39
35
Next-generation sequencing: emerging lessons on the origins of human cancer
Current Opinion in Oncology
2011
36
36
Melatonin protects spermatogonia from the stress of chemotherapy and oxidation via eliminating reactive oxidative species
Free Radical Biology and Medicine
2019
36
37
Fen1 mutations that specifically disrupt its interaction with PCNA cause aneuploidy-associated cancer
Cell Research
2011
35
38
Longitudinal epigenetic and gene expression profiles analyzed by three-component analysis reveal down-regulation of genes involved in protein translation in human aging
Nucleic Acids Research
2015
35
39
t-Darpp Activates IGF-1R Signaling to Regulate Glucose Metabolism in Trastuzumab-Resistant Breast Cancer Cells
Clinical Cancer Research
2018
35
40
Sex-Specific Dynamics of Global Chromatin Changes in Fetal Mouse Germ Cells
PLoS ONE
2011
35
41
ATRA-Induced Cellular Differentiation and CD38 Expression Inhibits Acquisition of BCR-ABL Mutations for CML Acquired Resistance
PLoS Genetics
2014
31
42
Single Base Resolution Analysis of 5-Methylcytosine and 5-Hydroxymethylcytosine by RRBS and TAB-RRBS
Methods in Molecular Biology
2015
31
43
Gamma Irradiation Does Not Induce Detectable Changes in DNA Methylation Directly following Exposure of Human Cells
PLoS ONE
2012
31
44
HP1β Is a Biomarker for Breast Cancer Prognosis and PARP Inhibitor Therapy
PLoS ONE
2015
29
45
HDAC1,2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia
Leukemia
2018
29
46
Androgen (dihydrotestosterone)–mediated regulation of food intake and obesity in female mice
Journal of Steroid Biochemistry and Molecular Biology
2013
28
47
Roles of SIRT1 in leukemogenesis
Current Opinion in Hematology
2013
28
48
Sirtuins in Hematological Aging and Malignancy
Critical Reviews in Oncogenesis
2013
28
49
Characterization of patient-derived tumor xenografts (PDXs) as models for estrogen receptor positive (ER+HER2− and ER+HER2+) breast cancers
Journal of Steroid Biochemistry and Molecular Biology
2017
26
50
SIRT1 and LSD1 competitively regulate KU70 functions in DNA repair and mutation acquisition in cancer cells
Oncotarget
2016
26
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