| # | Title | Journal | Year | Citations |
|---|
| 1 | The role of extracellular histone in organ injury | Cell Death and Disease | 2017 | 216 |
| 2 | Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer | British Journal of Cancer | 2002 | 205 |
| 3 | Prostate cancer cell malignancy via modulation of HIF-1α pathway with isoflurane and propofol alone and in combination | British Journal of Cancer | 2014 | 203 |
| 4 | The epidemiology of preterm labour | BJOG: an International Journal of Obstetrics and Gynaecology | 2005 | 199 |
| 5 | High tidal volume upregulates intrapulmonary cytokines in an in vivo mouse model of ventilator-induced lung injury | Journal of Applied Physiology | 2003 | 187 |
| 6 | Gastrointestinal complications of pelvic radiotherapy: are they of any importance? | Gut | 2005 | 178 |
| 7 | Isoflurane, a Commonly Used Volatile Anesthetic, Enhances Renal Cancer Growth and Malignant Potential via the Hypoxia-inducible Factor Cellular Signaling Pathway In Vitro | Anesthesiology | 2013 | 177 |
| 8 | Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurons by activating both the cannabinoid 1 receptor and the vanilloid receptor 1in vitro | European Journal of Neuroscience | 2003 | 168 |
| 9 | Effects of dexmedetomidine on perioperative stress, inflammation, and immune function: systematic review and meta-analysis | British Journal of Anaesthesia | 2019 | 168 |
| 10 | Xenon Preconditioning Reduces Brain Damage from Neonatal Asphyxia in Rats | Journal of Cerebral Blood Flow and Metabolism | 2006 | 164 |
| 11 | Inflammation Triggered by SARS-CoV-2 and ACE2 Augment Drives Multiple Organ Failure of Severe COVID-19: Molecular Mechanisms and Implications | Inflammation | 2021 | 162 |
| 12 | Alveolar macrophage-derived microvesicles mediate acute lung injury | Thorax | 2016 | 148 |
| 13 | The role of microglia in the pathobiology of neuropathic pain development: what do we know? | British Journal of Anaesthesia | 2017 | 145 |
| 14 | Increased capsaicin receptor TRPV1 in skin nerve fibres and related vanilloid receptors TRPV3 and TRPV4 in keratinocytes in human breast pain | BMC Women's Health | 2005 | 142 |
| 15 | Where Does HIV Live? | New England Journal of Medicine | 2004 | 137 |
| 16 | Role of necroptosis in the pathogenesis of solid organ injury | Cell Death and Disease | 2015 | 122 |
| 17 | Maternal blood pressure in pregnancy, birth weight, and perinatal mortality in first births: prospective study | BMJ: British Medical Journal | 2004 | 113 |
| 18 | Time- and Concentration-Dependent Effects of Dissolution Products of 58S Sol–Gel Bioactive Glass on Proliferation and Differentiation of Murine and Human Osteoblasts | Tissue Engineering | 2004 | 113 |
| 19 | Propofol compared with sevoflurane general anaesthesia is associated with decreased delayed neurocognitive recovery in older adults | British Journal of Anaesthesia | 2018 | 109 |
| 20 | Mechanisms of early pulmonary neutrophil sequestration in ventilator-induced lung injury in mice | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2004 | 106 |
| 21 | Complex regional pain syndrome: a recent update | Burns and Trauma | 2017 | 106 |
| 22 | Dexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis | Cell Death and Disease | 2019 | 106 |
| 23 | Distribution of Adipose Tissue in the Newborn | Pediatric Research | 2004 | 105 |
| 24 | Xenon and Sevoflurane Protect against Brain Injury in a Neonatal Asphyxia Model | Anesthesiology | 2008 | 101 |
| 25 | TNF-Induced Death Signaling Triggers Alveolar Epithelial Dysfunction in Acute Lung Injury | Journal of Immunology | 2013 | 99 |
| 26 | Resolution of acute lung injury and inflammation: a translational mouse model | European Respiratory Journal | 2012 | 98 |
| 27 | Clearance of Circulating Tumor Cells After Excision of Primary Colorectal Cancer | Annals of Surgery | 2002 | 96 |
| 28 | Accuracy of Investigations for Asymptomatic Colorectal Liver Metastases | Diseases of the Colon and Rectum | 2002 | 95 |
| 29 | Reactive Oxygen Species and p38 Mitogen-activated Protein Kinase Mediate Tumor Necrosis Factor α-Converting Enzyme (TACE/ADAM-17) Activation in Primary Human Monocytes | Journal of Biological Chemistry | 2011 | 95 |
| 30 | Impact of isoflurane on malignant capability of ovarian cancer in vitro | British Journal of Anaesthesia | 2015 | 93 |
| 31 | Molecular mechanisms of brain-derived neurotrophic factor in neuro-protection: Recent developments | Brain Research | 2017 | 93 |
| 32 | Role of Toll-like receptor-4 in renal graft ischemia-reperfusion injury | American Journal of Physiology - Renal Physiology | 2014 | 92 |
| 33 | Necroptosis and parthanatos are involved in remote lung injury after receiving ischemic renal allografts in rats | Kidney International | 2015 | 86 |
| 34 | Pelvic connective tissue resilience decreases with vaginal delivery, menopause and uterine prolapse | British Journal of Surgery | 2003 | 82 |
| 35 | Role of circulating tumour cells in predicting recurrence after excision of primary colorectal carcinoma | British Journal of Surgery | 2007 | 82 |
| 36 | Maternal Temperature Monitoring During Labor: Concordance and Variability Among Monitoring Sites | Obstetrics and Gynecology | 2004 | 81 |
| 37 | THIS ARTICLE HAS BEEN RETRACTED Activation of capsaicin‐sensitive primary sensory neurones induces anandamide production and release | Journal of Neurochemistry | 2003 | 80 |
| 38 | Inflammatory mediators convert anandamide into a potent activator of the vanilloid type 1 transient receptor potential receptor in nociceptive primary sensory neurons | Neuroscience | 2005 | 80 |
| 39 | PI3K/Akt pathway-mediated HO-1 induction regulates mitochondrial quality control and attenuates endotoxin-induced acute lung injury | Laboratory Investigation | 2019 | 78 |
| 40 | Immune dysregulation in human immunodeficiency virus infection: know it, fix it, prevent it? | Journal of Internal Medicine | 2009 | 77 |
| 41 | Transient receptor potential ion channels in primary sensory neurons as targets for novel analgesics | British Journal of Pharmacology | 2014 | 76 |
| 42 | Possible mechanisms of cannabinoid-induced antinociception in the spinal cord | European Journal of Pharmacology | 2001 | 74 |
| 43 | The Impact of Surgery and Anesthesia on Post-Operative Cognitive Decline and Alzheimer's Disease Development: Biomarkers and Preventive Strategies | Journal of Alzheimer's Disease | 2014 | 71 |
| 44 | Cannabinoid 1 receptors are expressed by nerve growth factor- and glial cell-derived neurotrophic factor-responsive primary sensory neurones | Neuroscience | 2002 | 68 |
| 45 | Seasonal patterns and preterm birth: a systematic review of the literature and an analysis in a London-based cohort | BJOG: an International Journal of Obstetrics and Gynaecology | 2006 | 67 |
| 46 | Lasting effects of general anesthetics on the brain in the young and elderly: “mixed picture” of neurotoxicity, neuroprotection and cognitive impairment | Journal of Anesthesia | 2019 | 67 |
| 47 | Hepatic ischemia-reperfusion injury in liver transplant setting: mechanisms and protective strategies | Journal of Biomedical Research | 2019 | 65 |
| 48 | Differential roles of p55 and p75 tumor necrosis factor receptors on stretch-induced pulmonary edema in mice | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2007 | 62 |
| 49 | Mobilization and Margination of Bone Marrow Gr-1highMonocytes during Subclinical Endotoxemia Predisposes the Lungs toward Acute Injury | Journal of Immunology | 2009 | 61 |
| 50 | Dexmedetomidine Attenuates Oxidative Stress Induced Lung Alveolar Epithelial Cell ApoptosisIn Vitro | Oxidative Medicine and Cellular Longevity | 2015 | 61 |
