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Top Articles

#TitleJournalYearCitations
1CXCL1–CXCR2 axis mediates angiotensin II-induced cardiac hypertrophy and remodelling through regulation of monocyte infiltrationEuropean Heart Journal2018192
2Hypoxia inducible factor as a therapeutic target for atherosclerosisEuropean Heart Journal2018154
3Senescent Cardiac Fibroblast Is Critical for Cardiac Fibrosis after Myocardial InfarctionPLoS ONE2013145
4Inhibition of Toll-like receptor 2 reduces cardiac fibrosis by attenuating macrophage-mediated inflammationCardiovascular Research2014110
5Fat-Specific Sirt6 Ablation Sensitizes Mice to High-Fat Diet–Induced Obesity and Insulin Resistance by Inhibiting LipolysisDiabetes2017104
6Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neuronsAutophagy202198
7Mesenchymal stem cells and vascular regenerationMicrocirculation201774
8The role of the vagal pathway and gastric dopamine in the gastroparesis of rats after a 6‐hydroxydopamine microinjection in the substantia nigraActa Physiologica201469
9IGF-1 Alleviates NMDA-Induced Excitotoxicity in Cultured Hippocampal Neurons Against Autophagy via the NR2B/PI3K-AKT-mTOR PathwayJournal of Cellular Physiology201466
10The Notch γ-secretase inhibitor ameliorates kidney fibrosis via inhibition of TGF-β/Smad2/3 signaling pathway activationInternational Journal of Biochemistry and Cell Biology201464
11Hypoxia inducible factor 1α in vascular smooth muscle cells promotes angiotensin II-induced vascular remodeling via activation of CCL7-mediated macrophage recruitmentCell Death and Disease201954
12β1-Adrenoceptor Autoantibodies from DCM Patients Enhance the Proliferation of T Lymphocytes through the β1-AR/cAMP/PKA and p38 MAPK PathwaysPLoS ONE201250
13A soluble receptor for advanced glycation end-products inhibits myocardial apoptosis induced by ischemia/reperfusion via the JAK2/STAT3 pathwayApoptosis: an International Journal on Programmed Cell Death201546
14Aldehyde dehydrogenase 2 protects against oxidative stress associated with pulmonary arterial hypertensionRedox Biology201746
15Proliferation in cardiac fibroblasts induced by β1-adrenoceptor autoantibody and the underlying mechanismsScientific Reports201645
16Protection against doxorubicin-induced myocardial dysfunction in mice by cardiac-specific expression of carboxyl terminus of hsp70-interacting proteinScientific Reports201644
17Novel Clinical Evidence of an Association between Homocysteine and Insulin Resistance in Patients with Hypothyroidism or Subclinical HypothyroidismPLoS ONE201544
18Transfer of mitochondria from mesenchymal stem cells derived from induced pluripotent stem cells attenuates hypoxia-ischemia-induced mitochondrial dysfunction in PC12 cellsNeural Regeneration Research202044
19Alteration of enteric monoamines with monoamine receptors and colonic dysmotility in 6-hydroxydopamine–induced Parkinson's disease ratsTranslational Research201543
20Biological characteristics of IL-6 and related intestinal diseasesInternational Journal of Biological Sciences202141
21CDC20 regulates cardiac hypertrophy via targeting LC3-dependent autophagyTheranostics201839
22Berberine is an insulin secretagogue targeting the KCNH6 potassium channelNature Communications202139
23Ubiquitin‐activating enzyme E1 inhibitor PYR41 attenuates angiotensin II‐induced activation of dendritic cells via the IκBa/NF‐κB and MKP1/ERK/STAT1 pathwaysImmunology201438
24Unusual localization and translocation of TRPV4 protein in cultured ventricular myocytes of the neonatal ratEuropean Journal of Histochemistry201237
25NADPH oxidases mediate a cellular “memory” of angiotensin II stress in hypertensive cardiac hypertrophyFree Radical Biology and Medicine201336
26Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitisHepatology202336
27YAP‐TEAD mediates PPAR α–induced hepatomegaly and liver regeneration in miceHepatology202235
28Binding of Dickkopf-3 to CXCR7 Enhances Vascular Progenitor Cell Migration and Degradable Graft RegenerationCirculation Research201834
29CD1d-dependent natural killer T cells attenuate angiotensin II-induced cardiac remodelling via IL-10 signalling in miceCardiovascular Research201934
30From Hyper- to Hypoinsulinemia and Diabetes: Effect of KCNH6 on Insulin SecretionCell Reports201833
31Hepatocyte peroxisome proliferator-activated receptor α regulates bile acid synthesis and transportBiochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids201933
32Dopamine promotes colonic mucus secretion through dopamine D5receptor in ratsAmerican Journal of Physiology - Cell Physiology201932
33Rhubarb extract relieves constipation by stimulating mucus production in the colon and altering the intestinal floraBiomedicine and Pharmacotherapy202132
34Decreased autophagy induced by β1-adrenoceptor autoantibodies contributes to cardiomyocyte apoptosisCell Death and Disease201831
35Targeting IL-17 attenuates hypoxia-induced pulmonary hypertension through downregulation of β-cateninThorax201930
36Cardiac Specific Overexpression of Mitochondrial Omi/HtrA2 Induces Myocardial Apoptosis and Cardiac DysfunctionScientific Reports201628
37Myelocytomatosis‐Protein Arginine N‐Methyltransferase 5 Axis Defines the Tumorigenesis and Immune Response in Hepatocellular CarcinomaHepatology202128
38The role of hypoxia-inducible factors in cardiovascular diseasesHepatology202227
39Distinctive expression and cellular distribution of dopamine receptors in the pancreatic islets of ratsCell and Tissue Research201425
40No Direct Projection is Observed from the Substantia Nigra to the Dorsal Vagus Complex in the RatJournal of Parkinson's Disease201425
41Amelioration of Ethanol-Induced Hepatitis by Magnesium Isoglycyrrhizinate through Inhibition of Neutrophil Cell Infiltration and Oxidative DamageMediators of Inflammation201725
42Keratin 23 Is a Peroxisome Proliferator‐Activated Receptor Alpha–Dependent, MYC‐Amplified Oncogene That Promotes Hepatocyte ProliferationHepatology201925
43Transcriptome analysis of coding and long non-coding RNAs highlights the regulatory network of cascade initiation of permanent molars in miniature pigsBMC Genomics201724
44Sitagliptin Protects Cardiac Function by Reducing Nitroxidative Stress and Promoting Autophagy in Zucker Diabetic Fatty (ZDF) RatsCardiovascular Drugs and Therapy201824
45Emodin induces chloride secretion in rat distal colon through activation of mast cells and enteric neuronsBritish Journal of Pharmacology201223
46Expression and localization of TRPC proteins in rat ventricular myocytes at various developmental stagesCell and Tissue Research201423
47Genome-wide DNA methylation profile of developing deciduous tooth germ in miniature pigsBMC Genomics201623
48Soluble receptor for advanced glycation end-products protects against ischemia/reperfusion-induced myocardial apoptosis via regulating the ubiquitin proteasome systemFree Radical Biology and Medicine201623
49“Angiotensin II memory” contributes to the development of hypertension and vascular injury via activation of NADPH oxidaseLife Sciences201623
50Irisin Is Controlled by Farnesoid X Receptor and Regulates Cholesterol HomeostasisFrontiers in Pharmacology201923