# | Title | Journal | Year | Citations |
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1 | New Hepatocyte In Vitro Systems for Drug Metabolism: Metabolic Capacity and Recommendations for Application in Basic Research and Drug Development, Standard Operation Procedures | Drug Metabolism Reviews | 2003 | 248 |
2 | Comprehensive comparison of three different animal models for systemic inflammation | Journal of Biomedical Science | 2017 | 166 |
3 | Protective effects of vitamin E and C on cisplatin nephrotoxicity in developing rats | Archives of Toxicology | 1997 | 151 |
4 | Comparison of immunoreactive score, HER2/neu score and H score for the immunohistochemical evaluation of somatostatin receptors in bronchopulmonary neuroendocrine neoplasms | Histopathology | 2015 | 123 |
5 | Agonist-selective patterns of µ-opioid receptor phosphorylation revealed by phosphosite-specific antibodies | British Journal of Pharmacology | 2011 | 118 |
6 | Differentiation of Opioid Drug Effects by Hierarchical Multi-Site Phosphorylation | Molecular Pharmacology | 2013 | 113 |
7 | Adverse drug reactions in Germany: direct costs of internal medicine hospitalizations | Pharmacoepidemiology and Drug Safety | 2011 | 102 |
8 | Fate of extrahepatic human stem and precursor cells after transplantation into mouse livers | Hepatology | 2007 | 92 |
9 | Self-Medication with Over-the-Counter and Prescribed Drugs Causing Adverse-Drug-Reaction-Related Hospital Admissions: Results of a Prospective, Long-Term Multi-Centre Study | Drug Safety | 2014 | 85 |
10 | CXCR7 prevents excessive CXCL12-mediated downregulation of CXCR4 in migrating cortical interneurons | Development (Cambridge) | 2014 | 68 |
11 | Asymmetrical (ADMA) and symmetrical dimethylarginine (SDMA) as potential risk factors for cardiovascular and renal outcome in chronic kidney disease – possible candidates for paradoxical epidemiology? | Amino Acids | 2006 | 65 |
12 | Design, synthesis and biological evaluation of D-ring opened galantamine analogs as multifunctional anti-Alzheimer agents | European Journal of Medicinal Chemistry | 2014 | 59 |
13 | Influence of high-dose methotrexate therapy (HD-MTX) on glomerular and tubular kidney function | Medical and Pediatric Oncology | 2003 | 57 |
14 | Morphology and cytochrome P450 isoforms expression in precision-cut rat liver slices | Toxicology | 2001 | 56 |
15 | The garlic ingredient diallyl sulfide inhibits cytochrome P450 2E1 dependent bioactivation of acrylamide to glycidamide | Toxicology Letters | 2006 | 56 |
16 | Suitability of 5/6 nephrectomy (5/6NX) for the induction of interstitial renal fibrosis in rats – Influence of sex, strain, and surgical procedure | Experimental and Toxicologic Pathology | 2006 | 55 |
17 | MK2/3 Are Pivotal for IL-33–Induced and Mast Cell–Dependent Leukocyte Recruitment and the Resulting Skin Inflammation | Journal of Immunology | 2016 | 54 |
18 | Hierarchical Organization of Multi-Site Phosphorylation at the CXCR4 C Terminus | PLoS ONE | 2013 | 52 |
19 | Correlations between spin equilibrium shift, reduction rate, and N-demethylation activity in liver microsomal cytochrome P-450 and a series of benzphetamine analogues as substrates | Biochemical Pharmacology | 1983 | 48 |
20 | The hepatic gluthathione system — influences of xenobiotics | Experimental Pathology | 1990 | 48 |
21 | Lipid peroxidation in thioacetamide-induced macronodular rat liver cirrhosis | Archives of Toxicology | 1991 | 47 |
22 | Heterologous regulation of agonist‐independent μ‐opioid receptor phosphorylation by protein kinase C | British Journal of Pharmacology | 2014 | 45 |
23 | Loss of Morphine Reward and Dependence in Mice Lacking G Protein–Coupled Receptor Kinase 5 | Biological Psychiatry | 2014 | 45 |
24 | Phenotypic and Genotypic Characterization of Carcinomas of the Papilla of Vater Has Prognostic and Putative Therapeutic Implications | American Journal of Clinical Pathology | 2011 | 44 |
25 | Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system | Development (Cambridge) | 2014 | 44 |
26 | Differential Expression of Somatostatin Receptor Subtype 1–5 Proteins in Numerous Human Normal Tissues | Experimental and Clinical Endocrinology and Diabetes | 2012 | 43 |
27 | CXC Chemokine Receptor 7 (CXCR7) Regulates CXCR4 Protein Expression and Capillary Tuft Development in Mouse Kidney | PLoS ONE | 2012 | 40 |
28 | Beneficial effect of acetylcysteine on cisplatin nephrotoxicity in rats | Journal of Applied Toxicology | 1993 | 38 |
29 | Effects of vaporized perfluorohexane and partial liquid ventilation on regional distribution of alveolar damage in experimental lung injury | Intensive Care Medicine | 2007 | 38 |
30 | Determination of the glomerular filtration rate (GFR): methodological problems, age-dependence, consequences of various surgical interventions, and the influence of different drugs and toxic substances | Physiological Research | 1999 | 38 |
31 | Glutathione synthesis and export in experimental liver cirrhosis induced by thioacetamide: Relations to ultrastructural changes | Experimental Pathology | 1989 | 37 |
32 | Comparative nephrotoxicity of some antitumour-active platinum and ruthenium complexes in rats | Journal of Applied Toxicology | 1998 | 37 |
33 | Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer’s disease | Acta Neuropathologica | 2015 | 36 |
34 | Agonist-selective NOP receptor phosphorylation correlates in vitro and in vivo and reveals differential post-activation signaling by chemically diverse agonists | Science Signaling | 2019 | 36 |
35 | Enzymes of glutathione synthesis in dog skeletal muscles and their response to training | Acta Physiologica Scandinavica | 1993 | 35 |
36 | Monooxygenation, cytochrome P450-mRNA expression and other functions in precision-cut rat liver slices | Experimental and Toxicologic Pathology | 1998 | 35 |
37 | Intermediate Progenitors Facilitate Intracortical Progression of Thalamocortical Axons and Interneurons through CXCL12 Chemokine Signaling | Journal of Neuroscience | 2015 | 35 |
38 | Rapid Dephosphorylation of G Protein-coupled Receptors by Protein Phosphatase 1β Is Required for Termination of β-Arrestin-dependent Signaling | Journal of Biological Chemistry | 2011 | 34 |
39 | Application of cryopreserved precision-cut liver slices in pharmacotoxicology — principles, literature data and own investigations with special reference to CYP1A1-mRNA induction | Experimental and Toxicologic Pathology | 1998 | 33 |
40 | Differential somatostatin and CXCR4 chemokine receptor expression in MALT-type lymphoma of gastric and extragastric origin | Journal of Cancer Research and Clinical Oncology | 2016 | 33 |
41 | Preventable ADRs leading to hospitalization — results of a long-term prospective safety study with 6,427 ADR cases focusing on elderly patients | Expert Opinion on Drug Safety | 2018 | 33 |
42 | Distinct Waves from the Hemogenic Endothelium Give Rise to Layered Lymphoid Tissue Inducer Cell Ontogeny | Cell Reports | 2020 | 33 |
43 | Comparative evaluation of three proliferation markers, Ki-67, TOP2A, and RacGAP1, in bronchopulmonary neuroendocrine neoplasms: Issues and prospects | Oncotarget | 0 | 33 |
44 | Induction of cytochrome P450 2B1-mRNA and pentoxyresorufin O-depentylation after exposure of precision-cut rat liver slices to phenobarbital | Toxicology | 2000 | 32 |
45 | A Switch of G Protein-Coupled Receptor Binding Preference from Phosphoinositide 3-Kinase (PI3K)–p85 to Filamin A Negatively Controls the PI3K Pathway | Molecular and Cellular Biology | 2012 | 32 |
46 | The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors | Journal of Experimental Medicine | 2019 | 32 |
47 | Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice | Arthritis Research and Therapy | 2011 | 31 |
48 | CXCR4 prevents dispersion of granule neuron precursors in the adult dentate gyrus | Hippocampus | 2013 | 31 |
49 | Cell-Autonomous Regulation of Mu-Opioid Receptor Recycling by Substance P | Cell Reports | 2015 | 30 |
50 | Evaluation of Homobivalent Carbolines as Designed Multiple Ligands for the Treatment of Neurodegenerative Disorders | Journal of Medicinal Chemistry | 2015 | 29 |