| # | Title | Journal | Year | Citations |
|---|
| 1 | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease | Nature Genetics | 2013 | 3,741 |
| 2 | Discovery and refinement of loci associated with lipid levels | Nature Genetics | 2013 | 2,641 |
| 3 | New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk | Nature Genetics | 2010 | 1,982 |
| 4 | Genetics of rheumatoid arthritis contributes to biology and drug discovery | Nature | 2014 | 1,974 |
| 5 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 6 | Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study | Lancet, The | 2012 | 1,937 |
| 7 | Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility | Nature Genetics | 2014 | 959 |
| 8 | The genetic architecture of type 2 diabetes | Nature | 2016 | 952 |
| 9 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
| 10 | Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci | Nature Neuroscience | 2014 | 800 |
| 11 | Common variants associated with plasma triglycerides and risk for coronary artery disease | Nature Genetics | 2013 | 754 |
| 12 | Assessing the impact of population stratification on genetic association studies | Nature Genetics | 2004 | 734 |
| 13 | Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia | Journal of the American College of Cardiology | 2016 | 723 |
| 14 | Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction | Nature | 2015 | 581 |
| 15 | Progress and Promise of Genome-Wide Association Studies for Human Complex Trait Genetics | Genetics | 2011 | 486 |
| 16 | Exome-wide association study of plasma lipids in >300,000 individuals | Nature Genetics | 2017 | 470 |
| 17 | Methods for High-Density Admixture Mapping of Disease Genes | American Journal of Human Genetics | 2004 | 437 |
| 18 | Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk | Nature Genetics | 2017 | 426 |
| 19 | A High-Density Admixture Map for Disease Gene Discovery in African Americans | American Journal of Human Genetics | 2004 | 416 |
| 20 | Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis | Nature Genetics | 2012 | 402 |
| 21 | A transcriptomic atlas of aged human microglia | Nature Communications | 2018 | 375 |
| 22 | The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals | Nature Genetics | 2016 | 362 |
| 23 | Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes | Nature Genetics | 2018 | 356 |
| 24 | Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population | PLoS Genetics | 2014 | 351 |
| 25 | ANGPTL3 Deficiency and Protection Against Coronary Artery Disease | Journal of the American College of Cardiology | 2017 | 348 |
| 26 | The trans-ancestral genomic architecture of glycemic traits | Nature Genetics | 2021 | 341 |
| 27 | The landscape of recombination in African Americans | Nature | 2011 | 319 |
| 28 | Evidence of widespread selection on standing variation in Europe at height-associated SNPs | Nature Genetics | 2012 | 315 |
| 29 | Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration | Nature Genetics | 2013 | 311 |
| 30 | A rare penetrant mutation in CFH confers high risk of age-related macular degeneration | Nature Genetics | 2011 | 291 |
| 31 | Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project | PLoS Genetics | 2011 | 290 |
| 32 | Haplotype Structure and Genotype-Phenotype Correlations of the Sulfonylurea Receptor and the Islet ATP-Sensitive Potassium Channel Gene Region | Diabetes | 2004 | 284 |
| 33 | Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension | Nature Genetics | 2016 | 261 |
| 34 | Rare Complete Knockouts in Humans: Population Distribution and Significant Role in Autism Spectrum Disorders | Neuron | 2013 | 242 |
| 35 | Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci | American Journal of Human Genetics | 2012 | 239 |
| 36 | Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder | Science | 2018 | 234 |
| 37 | Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 231 |
| 38 | De novo variants in neurodevelopmental disorders with epilepsy | Nature Genetics | 2018 | 230 |
| 39 | Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2 | Proceedings of the National Academy of Sciences of the United States of America | 2018 | 230 |
| 40 | The (in)famous GWAS P-value threshold revisited and updated for low-frequency variants | European Journal of Human Genetics | 2016 | 225 |
| 41 | New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes | PLoS Genetics | 2012 | 216 |
| 42 | Quantifying genetic effects on disease mediated by assayed gene expression levels | Nature Genetics | 2020 | 191 |
| 43 | Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease | Nature Genetics | 2017 | 190 |
| 44 | Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels | Journal of the American College of Cardiology | 2016 | 186 |
| 45 | Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility | Nature Communications | 2015 | 173 |
| 46 | Directional dominance on stature and cognition in diverse human populations | Nature | 2015 | 173 |
| 47 | Meta-analysis of gene-environment interaction: joint estimation of SNP and SNP × environment regression coefficients | Genetic Epidemiology | 2011 | 158 |
| 48 | Estimating the selective effects of heterozygous protein-truncating variants from human exome data | Nature Genetics | 2017 | 157 |
| 49 | Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility | Nature Communications | 2015 | 154 |
| 50 | Common variants at 6p21.1 are associated with large artery atherosclerotic stroke | Nature Genetics | 2012 | 152 |
