2.5K
Articles
156.2K
Citations
4.3
avg. Impact Factor
186
h-index

Most Cited Articles of Harvard Medical School in 2007

TitleJournalYearCitations
Renal clearance of quantum dotsNature Biotechnology20073.3K
PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinibCancer Research2007589
The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and diseaseNature Reviews Molecular Cell Biology2007521
Germline gain-of-function mutations in SOS1 cause Noonan syndromeNature Genetics2007447
BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutationsPLoS Medicine2007376
Compact cysteine-coated CdSe(ZnCdS) quantum dots for in vivo applicationsJournal of the American Chemical Society2007361
Post-translational modifications and regulation of the RAS superfamily of GTPases as anticancer targetsNature Reviews Drug Discovery2007351
Extracellular heat shock proteins in cell signalingFEBS Letters2007247
The role of Shp2 (PTPN11) in cancerCurrent Opinion in Genetics and Development2007200
B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunityImmunity2007193
Extracellular heat shock proteins in cell signaling and immunityAnnals of the New York Academy of Sciences2007175
Mechanisms for Hsp70 secretion: crossing membranes without a leaderMethods2007149
Nonreceptor protein-tyrosine phosphatases in immune cell signalingAnnual Review of Immunology2007141
Pooled analysis of the prospective trials of gefitinib monotherapy for EGFR-mutant non-small cell lung cancersLung Cancer2007140
Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammalsProceedings of the National Academy of Sciences of the United States of America2007133
Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1BScience2007122
FOXP1: a potential therapeutic target in cancerExpert Opinion on Therapeutic Targets2007117
SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cellsCancer Research2007110
Structural basis for high-affinity peptide inhibition of human Pin1ACS Chemical Biology2007109
Opportunities and obstacles to combination targeted therapy in renal cell cancerClinical Cancer Research200795
Lymphatic drainage of the peritoneal space: a pattern dependent on bowel lymphaticsAnnals of Surgical Oncology200789
Targeting Cdc37 inhibits multiple signaling pathways and induces growth arrest in prostate cancer cellsCancer Research200775
Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressorsCancer Research200774
Synthesis of conjugatable bisphosphonates for molecular imaging of large animalsAngewandte Chemie - International Edition200774
Real-time intraoperative ureteral guidance using invisible near-infrared fluorescenceJournal of Urology200773