| Obesity and insulin resistance | Journal of Clinical Investigation | 2000 | 2.1K |
| Leptin | Annual Review of Physiology | 2000 | 1.3K |
| Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity | Journal of Clinical Investigation | 2000 | 656 |
| Energy metabolism in uncoupling protein 3 gene knockout mice | Journal of Biological Chemistry | 2000 | 515 |
| Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism | Diabetes | 2000 | 372 |
| Chemical characterization of leptin-activated neurons in the rat brain | Journal of Comparative Neurology | 2000 | 322 |
| Hormonal predictors of prostate cancer: a meta-analysis | Journal of Clinical Oncology | 2000 | 237 |
| Serum CTX: a new marker of bone resorption that shows treatment effect more often than other markers because of low coefficient of variability and large changes with bisphosphonate therapy | Calcified Tissue International | 2000 | 207 |
| Frataxin activates mitochondrial energy conversion and oxidative phosphorylation | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 194 |
| Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice | American Journal of Physiology - Endocrinology and Metabolism | 2000 | 162 |
| Leptin, nutrition, and the thyroid: the why, the wherefore, and the wiring | Journal of Clinical Investigation | 2000 | 148 |
| Does programmed cell death (apoptosis) play a role in the development of multiple organ dysfunction in critically ill patients? a review and a theoretical framework | Critical Care Medicine | 2000 | 145 |
| Role of leptin in reproduction | Annals of the New York Academy of Sciences | 2000 | 122 |
| Lipopolysaccharide activates specific populations of hypothalamic and brainstem neurons that project to the spinal cord | Journal of Neuroscience | 2000 | 122 |
| Postnatal regulation of hypothalamic neuropeptide expression by leptin: implications for energy balance and body weight regulation | Regulatory Peptides | 2000 | 120 |
| Relationship of EP(1-4) prostaglandin receptors with rat hypothalamic cell groups involved in lipopolysaccharide fever responses | Journal of Comparative Neurology | 2000 | 117 |
| Predictive value of serum and follicular fluid leptin concentrations during assisted reproductive cycles in normal women and in women with the polycystic ovarian syndrome | Human Reproduction | 2000 | 110 |
| Transcellular transport of leptin by the short leptin receptor isoform ObRa in Madin-Darby Canine Kidney cells | Endocrinology | 2000 | 101 |
| Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation | Journal of Biological Chemistry | 2000 | 82 |
| Leptin, nutrition, and reproduction: timing is everything | Journal of Clinical Endocrinology and Metabolism | 2000 | 71 |
| Leptin and the neuroendocrinology of fasting | Frontiers of Hormone Research | 2000 | 63 |
| Insulin-like growth factor 1 in hepatocellular carcinoma and metastatic liver cancer in men | International Journal of Cancer | 2000 | 62 |
| Decreased serum leptin in bulimia nervosa | Journal of Clinical Endocrinology and Metabolism | 2000 | 57 |
| cAMP response element-binding protein-binding protein mediates thyrotropin-releasing hormone signaling on thyrotropin subunit genes | Journal of Biological Chemistry | 2000 | 54 |
| Unlike leptin, ciliary neurotrophic factor does not reverse the starvation-induced changes of serum corticosterone and hypothalamic neuropeptide levels but induces expression of hypothalamic inhibitors of leptin signaling | Diabetes | 2000 | 45 |
