Renal clearance of quantum dots | Nature Biotechnology | 2007 | 3.3K |
The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease | Nature Reviews Molecular Cell Biology | 2007 | 521 |
Germline gain-of-function mutations in SOS1 cause Noonan syndrome | Nature Genetics | 2007 | 447 |
BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations | PLoS Medicine | 2007 | 376 |
Compact cysteine-coated CdSe(ZnCdS) quantum dots for in vivo applications | Journal of the American Chemical Society | 2007 | 361 |
Post-translational modifications and regulation of the RAS superfamily of GTPases as anticancer targets | Nature Reviews Drug Discovery | 2007 | 351 |
The role of Shp2 (PTPN11) in cancer | Current Opinion in Genetics and Development | 2007 | 200 |
B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity | Immunity | 2007 | 193 |
Nonreceptor protein-tyrosine phosphatases in immune cell signaling | Annual Review of Immunology | 2007 | 141 |
Pooled analysis of the prospective trials of gefitinib monotherapy for EGFR-mutant non-small cell lung cancers | Lung Cancer | 2007 | 140 |
Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1B | Science | 2007 | 122 |
FOXP1: a potential therapeutic target in cancer | Expert Opinion on Therapeutic Targets | 2007 | 117 |
SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells | Cancer Research | 2007 | 110 |
Structural basis for high-affinity peptide inhibition of human Pin1 | ACS Chemical Biology | 2007 | 109 |
Opportunities and obstacles to combination targeted therapy in renal cell cancer | Clinical Cancer Research | 2007 | 95 |
Lymphatic drainage of the peritoneal space: a pattern dependent on bowel lymphatics | Annals of Surgical Oncology | 2007 | 89 |
Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressors | Cancer Research | 2007 | 74 |
Synthesis of conjugatable bisphosphonates for molecular imaging of large animals | Angewandte Chemie - International Edition | 2007 | 74 |
Real-time intraoperative ureteral guidance using invisible near-infrared fluorescence | Journal of Urology | 2007 | 73 |
Filamin B mutations cause chondrocyte defects in skeletal development | Human Molecular Genetics | 2007 | 71 |
Letting go of the rope--aggressive treatment, hospice care, and open access | New England Journal of Medicine | 2007 | 70 |
Effects of the administration of high-dose interleukin-2 on immunoregulatory cell subsets in patients with advanced melanoma and renal cell cancer | Clinical Cancer Research | 2007 | 70 |
Sentinel lymph node mapping of invasive urinary bladder cancer in animal models using invisible light | European Urology | 2007 | 64 |
Analysis of the neutralization breadth of the anti-V3 antibody F425-B4e8 and re-assessment of its epitope fine specificity by scanning mutagenesis | Virology | 2007 | 64 |
Roles of CREB-binding protein (CBP)/p300 in respiratory epithelium tumorigenesis | Cell Research | 2007 | 63 |