| # | Title | Journal | Year | Citations |
|---|
| 1 | Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA) | Infection Control and Hospital Epidemiology | 2010 | 2,716 |
| 2 | Liver Biopsy | New England Journal of Medicine | 2001 | 2,016 |
| 3 | Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study | Lancet, The | 2013 | 1,476 |
| 4 | ACG Clinical Guidelines: Diagnosis and Management of Celiac Disease | American Journal of Gastroenterology | 2013 | 1,341 |
| 5 | The Oslo definitions for coeliac disease and related terms | Gut | 2013 | 1,300 |
| 6 | New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure | Nature | 2008 | 964 |
| 7 | Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology | Gut | 2014 | 870 |
| 8 | Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4 | Journal of Experimental Medicine | 2012 | 548 |
| 9 | Celiac Disease: From Pathogenesis to Novel Therapies | Gastroenterology | 2009 | 543 |
| 10 | Intravenous hydrocortisone premedication reduces antibodies to infliximab in Crohn's disease: A randomized controlled trial | Gastroenterology | 2003 | 538 |
| 11 | Hepatitis B virus infection | Nature Reviews Disease Primers | 2018 | 490 |
| 12 | A Mouse Model of Clostridium difficile–Associated Disease | Gastroenterology | 2008 | 446 |
| 13 | Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts’ Criteria | Nutrients | 2015 | 423 |
| 14 | Epidemiology and Natural History of Gastro-Oesophageal Reflux Disease | Digestion | 1992 | 404 |
| 15 | CLOSTRIDIUM DIFFICILEINFECTION | Annual Review of Medicine | 1998 | 403 |
| 16 | Hepatitis C: A Multifaceted Disease: Review of Extrahepatic Manifestations | Annals of Internal Medicine | 1995 | 400 |
| 17 | Linaclotide for Irritable Bowel Syndrome With Constipation: A 26-Week, Randomized, Double-blind, Placebo-Controlled Trial to Evaluate Efficacy and Safety | American Journal of Gastroenterology | 2012 | 374 |
| 18 | Enteric Glia Regulate Intestinal Barrier Function and Inflammation Via Release of S-Nitrosoglutathione | Gastroenterology | 2007 | 349 |
| 19 | Two Randomized Trials of Linaclotide for Chronic Constipation | New England Journal of Medicine | 2011 | 322 |
| 20 | Saccharomyces boulardii Protease Inhibits the Effects of Clostridium difficile Toxins A and B in Human Colonic Mucosa | Infection and Immunity | 1999 | 321 |
| 21 | A 12-Week, Randomized, Controlled Trial With a 4-Week Randomized Withdrawal Period to Evaluate the Efficacy and Safety of Linaclotide in Irritable Bowel Syndrome With Constipation | American Journal of Gastroenterology | 2012 | 318 |
| 22 | ASGE guideline on the role of endoscopy in the evaluation and management of choledocholithiasis | Gastrointestinal Endoscopy | 2019 | 316 |
| 23 | The P2X7 Receptor in Inflammatory Diseases: Angel or Demon? | Frontiers in Pharmacology | 2018 | 307 |
| 24 | Development of chronic colitis is dependent on the cytokine MIF | Nature Immunology | 2001 | 288 |
| 25 | Portal vein thrombosis: A review | American Journal of Medicine | 1992 | 282 |
| 26 | Ulcerative colitis | Lancet, The | 2002 | 273 |
| 27 | Functional variants in the LRRK2 gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease | Science Translational Medicine | 2018 | 273 |
| 28 | TLR4/MyD88/PI3K interactions regulate TLR4 signaling | Journal of Leukocyte Biology | 2009 | 272 |
| 29 | The placebo effect in irritable bowel syndrome trials: a meta-analysis1 | Neurogastroenterology and Motility | 2005 | 261 |
| 30 | Clostridium difficileInfection: A Worldwide Disease | Gut and Liver | 2014 | 247 |
| 31 | Nutritional Wheat Amylase-Trypsin Inhibitors Promote Intestinal Inflammation via Activation of Myeloid Cells | Gastroenterology | 2017 | 247 |
| 32 | Hepatitis B Virus X Protein Induces Hepatic Steatosis Via Transcriptional Activation of SREBP1 and PPARγ | Gastroenterology | 2007 | 245 |
| 33 | Short hairpin RNA–expressing bacteria elicit RNA interference in mammals | Nature Biotechnology | 2006 | 239 |
| 34 | Prospective Derivation and Validation of a Clinical Prediction Rule for Recurrent Clostridium difficile Infection | Gastroenterology | 2009 | 222 |
| 35 | The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase | Cell Metabolism | 2018 | 222 |
| 36 | New Consensus Definition of Acute Kidney Injury Accurately Predicts 30-Day Mortality in Patients With Cirrhosis and Infection | Gastroenterology | 2013 | 221 |
| 37 | Efficacy of Linaclotide for Patients With Chronic Constipation | Gastroenterology | 2010 | 216 |
| 38 | Saccharomyces boulardii protease inhibits Clostridium difficile toxin A effects in the rat ileum | Infection and Immunity | 1996 | 212 |
| 39 | Systematic Review and Meta-analysis on the Effects of Thiopurines on Birth Outcomes from Female and Male Patients with Inflammatory Bowel Disease | Inflammatory Bowel Diseases | 2013 | 211 |
| 40 | Kinetics of the histological, serological and symptomatic responses to gluten challenge in adults with coeliac disease | Gut | 2013 | 205 |
| 41 | Larazotide Acetate for Persistent Symptoms of Celiac Disease Despite a Gluten-Free Diet: A Randomized Controlled Trial | Gastroenterology | 2015 | 204 |
| 42 | Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 202 |
| 43 | Clostridium difficile toxin B is an inflammatory enterotoxin in human intestine | Gastroenterology | 2003 | 200 |
| 44 | Vascular Endothelial Growth Factor Promotes Fibrosis Resolution and Repair in Mice | Gastroenterology | 2014 | 196 |
| 45 | Primary gallbladder cancer: recognition of risk factors and the role of prophylactic cholecystectomy | American Journal of Gastroenterology | 2000 | 191 |
| 46 | Clinical Experience With Infliximab Therapy in 100 Patients With Crohn's Disease | American Journal of Gastroenterology | 2000 | 189 |
| 47 | Decreased Postnatal Docosahexaenoic and Arachidonic Acid Blood Levels in Premature Infants are Associated with Neonatal Morbidities | Journal of Pediatrics | 2011 | 188 |
| 48 | Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients | Gastroenterology | 2016 | 180 |
| 49 | Delivery of RNA Interference | Cell Cycle | 2006 | 176 |
| 50 | Alosetron controls bowel urgency and provides global symptom improvement in women with diarrhea-predominant irritable bowel syndrome | American Journal of Gastroenterology | 2001 | 174 |
