| # | Title | Journal | Year | Citations |
|---|
| 1 | Liver cirrhosis | Lancet, The | 2008 | 1,745 |
| 2 | Global Prevalence of Celiac Disease: Systematic Review and Meta-analysis | Clinical Gastroenterology and Hepatology | 2018 | 908 |
| 3 | Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients With Advanced Liver Disease | Gastroenterology | 2015 | 725 |
| 4 | IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease | PLoS Pathogens | 2013 | 364 |
| 5 | IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39 | Nature Immunology | 2013 | 294 |
| 6 | Targeting liver fibrosis: Strategies for development and validation of antifibrotic therapies | Hepatology | 2009 | 268 |
| 7 | Chylous ascites | American Journal of Gastroenterology | 2002 | 259 |
| 8 | Herbal hepatotoxicity | Journal of Hepatology | 2005 | 249 |
| 9 | Selective targeting of lysyl oxidase-like 2 (LOXL2) suppresses hepatic fibrosis progression and accelerates its reversal | Gut | 2017 | 225 |
| 10 | CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine | Cell Stem Cell | 2018 | 188 |
| 11 | Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease | Nature Biotechnology | 2013 | 176 |
| 12 | Lysyl oxidase activity contributes to collagen stabilization during liver fibrosis progression and limits spontaneous fibrosis reversal in mice | FASEB Journal | 2016 | 168 |
| 13 | Integrin αvβ6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies | Journal of Hepatology | 2008 | 159 |
| 14 | Standard assessments of frailty are validated predictors of mortality in hospitalized patients with cirrhosis | Hepatology | 2015 | 156 |
| 15 | EGFR blockade by cetuximab alone or as combination therapy for growth control of hepatocellular cancer | Biochemical Pharmacology | 2005 | 153 |
| 16 | Hepatitis C pharmacogenetics: State of the art in 2010 | Hepatology | 2011 | 131 |
| 17 | Hepatic hydrothorax | Alimentary Pharmacology and Therapeutics | 2004 | 127 |
| 18 | Extrahepatic Platelet-Derived Growth Factor-β, Delivered by Platelets, Promotes Activation of Hepatic Stellate Cells and Biliary Fibrosis in Mice | Gastroenterology | 2014 | 127 |
| 19 | A Quality Improvement Initiative Reduces 30-Day Rate of Readmission for Patients With Cirrhosis | Clinical Gastroenterology and Hepatology | 2016 | 124 |
| 20 | Tissue Transglutaminase Does Not Affect Fibrotic Matrix Stability or Regression of Liver Fibrosis in Mice | Gastroenterology | 2011 | 123 |
| 21 | The Performance of Vibration Controlled Transient Elastography in a US Cohort of Patients With Nonalcoholic Fatty Liver Disease | American Journal of Gastroenterology | 2016 | 122 |
| 22 | Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis | American Journal of Physiology - Renal Physiology | 2010 | 116 |
| 23 | Opioids in Gastroenterology: Treating Adverse Effects and Creating Therapeutic Benefits | Clinical Gastroenterology and Hepatology | 2017 | 110 |
| 24 | Blockade of IGF-1 receptor tyrosine kinase has antineoplastic effects in hepatocellular carcinoma cells | Biochemical Pharmacology | 2006 | 106 |
| 25 | Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease | Cell Metabolism | 2019 | 106 |
| 26 | Failure of Fibrotic Liver Regeneration in Mice Is Linked to a Severe Fibrogenic Response Driven by Hepatic Progenitor Cell Activation | American Journal of Pathology | 2013 | 99 |
| 27 | Integrin αvβ6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis, and tumorigenesis | Hepatology | 2016 | 93 |
| 28 | Encapsulating peritoneal sclerosis | World Journal of Gastroenterology | 2018 | 91 |
| 29 | Chylous ascites | American Journal of Gastroenterology | 2002 | 87 |
| 30 | Low Serum Vitamin D During Remission Increases Risk of Clinical Relapse in Patients With Ulcerative Colitis | Clinical Gastroenterology and Hepatology | 2017 | 87 |
| 31 | Vitamin D in inflammatory bowel disease | Current Opinion in Gastroenterology | 2018 | 87 |
| 32 | Clostridium difficile Strain NAP-1 Is Not Associated With Severe Disease in a Nonepidemic Setting | Clinical Gastroenterology and Hepatology | 2009 | 85 |
| 33 | Cell cycle arrest and apoptosis induction in hepatocellular carcinoma cells by HMG-CoA reductase inhibitors. Synergistic antiproliferative action with ligands of the peripheral benzodiazepine receptor | Journal of Hepatology | 2005 | 80 |
| 34 | Efficacy and Safety of Direct Acting Antivirals in Kidney Transplant Recipients with Chronic Hepatitis C Virus Infection | PLoS ONE | 2016 | 79 |
| 35 | The new paradigm of hepatitis C therapy: integration of oral therapies into best practices | Journal of Viral Hepatitis | 2013 | 78 |
| 36 | Sorafenib alone or as combination therapy for growth control of cholangiocarcinoma | Biochemical Pharmacology | 2007 | 74 |
| 37 | Aspirin use is associated with lower indices of liver fibrosis among adults in the United States | Alimentary Pharmacology and Therapeutics | 2016 | 74 |
| 38 | Hepatorenal Syndrome: A Dreaded Complication of End-Stage Liver Disease | American Journal of Gastroenterology | 2005 | 73 |
| 39 | A New Mdr2−/− Mouse Model of Sclerosing Cholangitis with Rapid Fibrosis Progression, Early-Onset Portal Hypertension, and Liver Cancer | American Journal of Pathology | 2015 | 71 |
| 40 | Systematic review with meta‐analysis: association of vitamin D status with clinical outcomes in adult patients with inflammatory bowel disease | Alimentary Pharmacology and Therapeutics | 2019 | 69 |
| 41 | Mechanisms of water and sodium retention in cirrhosis and the pathogenesis of ascites | Best Practice and Research in Clinical Endocrinology and Metabolism | 2003 | 67 |
| 42 | How, When, and for Whom Should We Perform Therapeutic Drug Monitoring? | Clinical Gastroenterology and Hepatology | 2020 | 62 |
| 43 | Broad-Spectrum Matrix Metalloproteinase Inhibition Curbs Inflammation and Liver Injury but Aggravates Experimental Liver Fibrosis in Mice | PLoS ONE | 2010 | 55 |
| 44 | Increased Morbidity and Mortality Associated with Falls Among Patients with Cirrhosis | American Journal of Medicine | 2018 | 53 |
| 45 | Provider Attitudes and Practices for Alcohol Screening, Treatment, and Education in Patients With Liver Disease: A Survey From the American Association for the Study of Liver Diseases Alcohol-Associated Liver Disease Special Interest Group | Clinical Gastroenterology and Hepatology | 2021 | 52 |
| 46 | A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook | Nature Reviews Gastroenterology and Hepatology | 2022 | 47 |
| 47 | The role of adenosine receptors A2A and A2B signaling in renal fibrosis | Kidney International | 2014 | 46 |
| 48 | Fibrosis as an End Point for Clinical Trials in Liver Disease: A Report of the International Fibrosis Group | Clinical Gastroenterology and Hepatology | 2006 | 44 |
| 49 | Eluxadoline Efficacy in IBS-D Patients Who Report Prior Loperamide Use | American Journal of Gastroenterology | 2017 | 43 |
| 50 | Hospital volume and mortality after transjugular intrahepatic portosystemic shunt creation in the United States | Hepatology | 2018 | 40 |
