41K
Articles
2M
Citations
3.7
avg. Impact Factor
496
h-index

Most Cited Articles of Harvard Medical School in 2004

TitleJournalYearCitations
Adipose tissue as an endocrine organJournal of Clinical Endocrinology and Metabolism20043.4K
Near-infrared fluorescent type II quantum dots for sentinel lymph node mappingNature Biotechnology20041.8K
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeysNature20041.5K
Cancer of the ovaryNew England Journal of Medicine20041.4K
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stressProceedings of the National Academy of Sciences of the United States of America20041.4K
Large-scale characterization of HeLa cell nuclear phosphoproteinsProceedings of the National Academy of Sciences of the United States of America20041.3K
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamusNature20041.3K
Cortical midline structures and the selfTrends in Cognitive Sciences20041.1K
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null miceCell2004957
Obesity wars: molecular progress confronts an expanding epidemicCell2004931
Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathwayProceedings of the National Academy of Sciences of the United States of America2004926
The LKB1 tumor suppressor negatively regulates mTOR signalingCancer Cell2004884
Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinomaJournal of Clinical Oncology2004847
Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular riskJournal of the American College of Cardiology2004816
Mitochondrial dysfunction and oxidative damage in parkin-deficient miceJournal of Biological Chemistry2004734
Leptin receptor signaling in POMC neurons is required for normal body weight homeostasisNeuron2004721
Relationship of MIC and bactericidal activity to efficacy of vancomycin for treatment of methicillin-resistant Staphylococcus aureus bacteremiaJournal of Clinical Microbiology2004703
Diagnosis and treatment of diabetic foot infectionsClinical Infectious Diseases2004701
Sleep-dependent learning and memory consolidationNeuron2004686
Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sitesJournal of Bone and Mineral Research2004643
OMERACT-OARSI initiative: Osteoarthritis Research Society International set of responder criteria for osteoarthritis clinical trials revisitedOsteoarthritis and Cartilage2004572
Risks of testosterone-replacement therapy and recommendations for monitoringNew England Journal of Medicine2004566
Region-specific leptin resistance within the hypothalamus of diet-induced obese miceEndocrinology2004563
Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumorsCancer Cell2004529
Enhanced partner preference in a promiscuous species by manipulating the expression of a single geneNature2004506