Adipose tissue as an endocrine organ | Journal of Clinical Endocrinology and Metabolism | 2004 | 3.4K |
Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping | Nature Biotechnology | 2004 | 1.8K |
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys | Nature | 2004 | 1.5K |
Cancer of the ovary | New England Journal of Medicine | 2004 | 1.4K |
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 1.4K |
Large-scale characterization of HeLa cell nuclear phosphoproteins | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 1.3K |
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus | Nature | 2004 | 1.3K |
Cortical midline structures and the self | Trends in Cognitive Sciences | 2004 | 1.1K |
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice | Cell | 2004 | 957 |
Obesity wars: molecular progress confronts an expanding epidemic | Cell | 2004 | 931 |
Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 926 |
The LKB1 tumor suppressor negatively regulates mTOR signaling | Cancer Cell | 2004 | 884 |
Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma | Journal of Clinical Oncology | 2004 | 847 |
Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk | Journal of the American College of Cardiology | 2004 | 816 |
Mitochondrial dysfunction and oxidative damage in parkin-deficient mice | Journal of Biological Chemistry | 2004 | 734 |
Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis | Neuron | 2004 | 721 |
Relationship of MIC and bactericidal activity to efficacy of vancomycin for treatment of methicillin-resistant Staphylococcus aureus bacteremia | Journal of Clinical Microbiology | 2004 | 703 |
Diagnosis and treatment of diabetic foot infections | Clinical Infectious Diseases | 2004 | 701 |
Sleep-dependent learning and memory consolidation | Neuron | 2004 | 686 |
Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites | Journal of Bone and Mineral Research | 2004 | 643 |
OMERACT-OARSI initiative: Osteoarthritis Research Society International set of responder criteria for osteoarthritis clinical trials revisited | Osteoarthritis and Cartilage | 2004 | 572 |
Risks of testosterone-replacement therapy and recommendations for monitoring | New England Journal of Medicine | 2004 | 566 |
Region-specific leptin resistance within the hypothalamus of diet-induced obese mice | Endocrinology | 2004 | 563 |
Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors | Cancer Cell | 2004 | 529 |
Enhanced partner preference in a promiscuous species by manipulating the expression of a single gene | Nature | 2004 | 506 |