| The phosphoinositide 3-kinase pathway | Science | 2002 | 4.5K |
| Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase | Nature Medicine | 2002 | 3.2K |
| Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres | Nature | 2002 | 2K |
| Multiscale entropy analysis of complex physiologic time series | Physical Review Letters | 2002 | 1.9K |
| Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase | Nature | 2002 | 1.6K |
| Fractal dynamics in physiology: alterations with disease and aging | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 1.4K |
| Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy | Journal of Clinical Oncology | 2002 | 1.3K |
| Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity | Nature | 2002 | 1.1K |
| Consensus-based method for risk adjustment for surgery for congenital heart disease | Journal of Thoracic and Cardiovascular Surgery | 2002 | 997 |
| Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1 | Nature Medicine | 2002 | 916 |
| Effect of nonstationarities on detrended fluctuation analysis | Physical Review E | 2002 | 681 |
| Celiac sprue | New England Journal of Medicine | 2002 | 670 |
| Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 661 |
| Comparative cytoarchitectonic analysis of the human and the macaque ventrolateral prefrontal cortex and corticocortical connection patterns in the monkey | European Journal of Neuroscience | 2002 | 658 |
| betaAR signaling required for diet-induced thermogenesis and obesity resistance | Science | 2002 | 633 |
| Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile | Clinical Infectious Diseases | 2002 | 596 |
| Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes | Nature | 2002 | 583 |
| What is physiologic complexity and how does it change with aging and disease? | Neurobiology of Aging | 2002 | 578 |
| Mutations in the O-mannosyltransferase gene POMT1 give rise to the severe neuronal migration disorder Walker-Warburg syndrome | American Journal of Human Genetics | 2002 | 573 |
| Pharmacological treatment of coronary artery disease with recombinant fibroblast growth factor-2: double-blind, randomized, controlled clinical trial | Circulation | 2002 | 567 |
| Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse | Nature Medicine | 2002 | 560 |
| Acupuncture: theory, efficacy, and practice | Annals of Internal Medicine | 2002 | 560 |
| TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization | Cell | 2002 | 546 |
| The central autonomic nervous system: conscious visceral perception and autonomic pattern generation | Annual Review of Neuroscience | 2002 | 544 |
| ASPM is a major determinant of cerebral cortical size | Nature Genetics | 2002 | 472 |
