| PhysioBank, PhysioToolkit, and PhysioNet: components of a new research resource for complex physiologic signals | Circulation | 2000 | 6.6K |
| Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway | Nature Medicine | 2000 | 2.3K |
| Obesity and insulin resistance | Journal of Clinical Investigation | 2000 | 2.1K |
| A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts | Hepatology | 2000 | 2K |
| Leptin | Annual Review of Physiology | 2000 | 1.3K |
| Towards a molecular understanding of adaptive thermogenesis | Nature | 2000 | 1.3K |
| Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein | Nature | 2000 | 964 |
| Impact of cancer-related fatigue on the lives of patients: new findings from the Fatigue Coalition | Oncologist | 2000 | 894 |
| Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination | Science | 2000 | 836 |
| Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis | Journal of Experimental Medicine | 2000 | 833 |
| An association between migraine and cutaneous allodynia | Annals of Neurology | 2000 | 792 |
| Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A | New England Journal of Medicine | 2000 | 789 |
| Left ventricular hypertrophy: pathogenesis, detection, and prognosis | Circulation | 2000 | 786 |
| Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor | Arthritis and Rheumatism | 2000 | 705 |
| Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations | Nature Genetics | 2000 | 700 |
| Transcranial magnetic stimulation in cognitive neuroscience--virtual lesion, chronometry, and functional connectivity | Current Opinion in Neurobiology | 2000 | 683 |
| Noninvasive coronary vessel wall and plaque imaging with magnetic resonance imaging | Circulation | 2000 | 680 |
| Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents | Nature | 2000 | 679 |
| Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity | Journal of Clinical Investigation | 2000 | 656 |
| The role of the chondrocyte in osteoarthritis | Arthritis and Rheumatism | 2000 | 570 |
| Leptin regulation of neuroendocrine systems | Frontiers in Neuroendocrinology | 2000 | 561 |
| Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance | Nature Medicine | 2000 | 546 |
| Modulation of corticospinal excitability by repetitive transcranial magnetic stimulation | Clinical Neurophysiology | 2000 | 538 |
| TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins | EMBO Journal | 2000 | 524 |
| Energy metabolism in uncoupling protein 3 gene knockout mice | Journal of Biological Chemistry | 2000 | 515 |
