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Top Articles

#TitleJournalYearCitations
1Nuclear m 6 A Reader YTHDC1 Regulates mRNA SplicingMolecular Cell20161,432
25-methylcytosine promotes mRNA export — NSUN2 as the methyltransferase and ALYREF as an m5C readerCell Research2017666
3m6A RNA Methylation Is Regulated by MicroRNAs and Promotes Reprogramming to PluripotencyCell Stem Cell2015483
43D Chromatin Structures of Mature Gametes and Structural Reprogramming during Mammalian EmbryogenesisCell2017415
5Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiationCell Research2017306
6A novel m6A reader Prrc2a controls oligodendroglial specification and myelinationCell Research2019250
7METTL3-mediated m6A modification is required for cerebellar developmentPLoS Biology2018216
8Capturing the interactome of newly transcribed RNANature Methods2018170
9METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidationCell Research2018146
10Key role for CTCF in establishing chromatin structure in human embryosNature2019131
11m6A modification suppresses ocular melanoma through modulating HINT2 mRNA translationMolecular Cancer2019114
12SIRT1 Regulates N6‐Methyladenosine RNA Modification in Hepatocarcinogenesis by Inducing RANBP2‐Dependent FTO SUMOylationHepatology2020101
13m6A: Signaling for mRNA splicingRNA Biology201696
14Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemiaCell Research201862
15Single-cell analysis of ploidy and the transcriptome reveals functional and spatial divergency in murine megakaryopoiesisBlood202159
16DNA methylation reprogramming of functional elements during mammalian embryonic developmentCell Discovery201851
17mRNA m6A plays opposite role in regulating UCP2 and PNPLA2 protein expression in adipocytesInternational Journal of Obesity201838
18Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic SyndromesCancer Discovery201838
19Aggressive NK-cell leukemia: clinical subtypes, molecular features, and treatment outcomesBlood Cancer Journal201737
20More than one antibody of individual B cells revealed by single-cell immune profilingCell Discovery201936
21The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double-strand break repairELife202034
22A Balance of Yki/Sd Activator and E2F1/Sd Repressor Complexes Controls Cell Survival and Affects Organ SizeDevelopmental Cell201732
23Human NOTCH4 is a key target of RUNX1 in megakaryocytic differentiationBlood201831
24Genome wide abnormal DNA methylome of human blastocyst in assisted reproductive technologyJournal of Genetics and Genomics201730
25SETD2-mediated crosstalk between H3K36me3 and H3K79me2 in MLL-rearranged leukemiaLeukemia201829
26Insight into novel RNA-binding activities via large-scale analysis of lncRNA-bound proteome and IDH1-bound transcriptomeNucleic Acids Research201929
27SETD2 mutations confer chemoresistance in acute myeloid leukemia partly through altered cell cycle checkpointsLeukemia201929
28Characterization of Cellular Heterogeneity and an Immune Subpopulation of Human MegakaryocytesAdvanced Science202129
29The m6A reading protein YTHDF3 potentiates tumorigenicity of cancer stem-like cells in ocular melanoma through facilitating CTNNB1 translationOncogene202229
30ANP32A regulates histone H3 acetylation and promotes leukemogenesisLeukemia201825
31Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancyJournal of Clinical Investigation201825
32Synthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancersNature Communications201825
33MYC promotes cancer progression by modulating m6A modifications to suppress target gene translationEMBO Reports202124
34Loss of Asxl2 leads to myeloid malignancies in miceNature Communications201723
35Expression profiling-based clustering of healthy subjects recapitulates classifications defined by clinical observation in Chinese medicineJournal of Genetics and Genomics201722
36Role of DNA methylation in altered gene expression patterns in adult zebrafish (Danio rerio) exposed to 3, 3’, 4, 4’, 5-pentachlorobiphenyl (PCB 126)Environmental Epigenetics201819
37Loss of Asxl1 Alters Self-Renewal and Cell Fate of Bone Marrow Stromal Cells, Leading to Bohring-Opitz-like Syndrome in MiceStem Cell Reports201618
38Deep RNA sequencing analysis of syncytialization-related genes during BeWo cell fusionReproduction201713
39Association between Promoter Methylation of Gene ERCC3 and Benzene HematotoxicityInternational Journal of Environmental Research and Public Health201712
40Benzene metabolite hydroquinone promotes DNA homologous recombination repair via the NF-κB pathwayCarcinogenesis201912
41Gut microbiome alterations and its link to corticosteroid resistance in immune thrombocytopeniaScience China Life Sciences202110
42Benzene induces rapid leukemic transformation after prolonged hematotoxicity in a murine modelLeukemia20218
43A Novel Variation in the Mitochondrial Complex I Assembly Factor NDUFAF5 Causes Isolated Bilateral Striatal Necrosis in ChildhoodFrontiers in Neurology20217
44Inherent bioelectrical parameters of hundreds of thousands of single leukocytes based on impedance flow cytometryCytometry Part A: the Journal of the International Society for Analytical Cytology20227
45Comparison of chromatin accessibility landscapes during early development of prefrontal cortex between rhesus macaque and humanNature Communications20227
46Endogenous DNA Damage and Repair EnzymesGenomics, Proteomics and Bioinformatics20166
47Risk stratification and outcomes of intracranial hemorrhage in patients with immune thrombocytopenia under 60 years of agePlatelets20216
48Tumor heterogeneity of acute myeloid leukemia: insights from single-cell sequencingBlood Science20195
49A risk score for predicting hospitalization for community-acquired pneumonia in ITP using nationally representative dataBlood Advances20205
50Development and validation of a prediction model (AHC) for early identification of refractory thrombotic thrombocytopenic purpura using nationally representative dataBritish Journal of Haematology20205