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Top Articles

#TitleJournalYearCitations
1Nuclear m 6 A Reader YTHDC1 Regulates mRNA SplicingMolecular Cell20161,432
2FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesisCell Research2014869
35-methylcytosine promotes mRNA export — NSUN2 as the methyltransferase and ALYREF as an m5C readerCell Research2017666
4Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiationCell Research2017306
5A novel m6A reader Prrc2a controls oligodendroglial specification and myelinationCell Research2019250
6Scleral hypoxia is a target for myopia controlProceedings of the National Academy of Sciences of the United States of America2018224
7METTL3-mediated m6A modification is required for cerebellar developmentPLoS Biology2018216
8Capturing the interactome of newly transcribed RNANature Methods2018170
9METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidationCell Research2018146
10m6A modification suppresses ocular melanoma through modulating HINT2 mRNA translationMolecular Cancer2019114
11SIRT1 Regulates N6‐Methyladenosine RNA Modification in Hepatocarcinogenesis by Inducing RANBP2‐Dependent FTO SUMOylationHepatology2020101
12m6A: Signaling for mRNA splicingRNA Biology201696
13Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemiaCell Research201862
14Scleral HIF-1α is a prominent regulatory candidate for genetic and environmental interactions in human myopia pathogenesisEBioMedicine202056
15mRNA m6A plays opposite role in regulating UCP2 and PNPLA2 protein expression in adipocytesInternational Journal of Obesity201838
16Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic SyndromesCancer Discovery201838
17Aggressive NK-cell leukemia: clinical subtypes, molecular features, and treatment outcomesBlood Cancer Journal201737
18A Balance of Yki/Sd Activator and E2F1/Sd Repressor Complexes Controls Cell Survival and Affects Organ SizeDevelopmental Cell201732
19Human NOTCH4 is a key target of RUNX1 in megakaryocytic differentiationBlood201831
20SETD2-mediated crosstalk between H3K36me3 and H3K79me2 in MLL-rearranged leukemiaLeukemia201829
21Insight into novel RNA-binding activities via large-scale analysis of lncRNA-bound proteome and IDH1-bound transcriptomeNucleic Acids Research201929
22Characterization of Cellular Heterogeneity and an Immune Subpopulation of Human MegakaryocytesAdvanced Science202129
23The m6A reading protein YTHDF3 potentiates tumorigenicity of cancer stem-like cells in ocular melanoma through facilitating CTNNB1 translationOncogene202229
24Metagenomic Profiling of Ocular Surface Microbiome Changes in Meibomian Gland Dysfunction202027
25Unique features of mutations revealed by sequentially reprogrammed induced pluripotent stem cellsNature Communications201526
26ANP32A regulates histone H3 acetylation and promotes leukemogenesisLeukemia201825
27Synthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancersNature Communications201825
28MYC promotes cancer progression by modulating m6A modifications to suppress target gene translationEMBO Reports202124
29Loss of Asxl2 leads to myeloid malignancies in miceNature Communications201723
30Loss of Asxl1 Alters Self-Renewal and Cell Fate of Bone Marrow Stromal Cells, Leading to Bohring-Opitz-like Syndrome in MiceStem Cell Reports201618
31Deep RNA sequencing analysis of syncytialization-related genes during BeWo cell fusionReproduction201713
32Association between Promoter Methylation of Gene ERCC3 and Benzene HematotoxicityInternational Journal of Environmental Research and Public Health201712
33Dysfunction of VIPR2 leads to myopia in humans and miceJournal of Medical Genetics202210
34Declines in PDE4B activity promote myopia progression through downregulation of scleral collagen expressionExperimental Eye Research20218
35Risk stratification and outcomes of intracranial hemorrhage in patients with immune thrombocytopenia under 60 years of agePlatelets20216
36Transcriptional and Spatial Heterogeneity of Mouse Megakaryocytes at Single-Cell ResolutionBlood20194
37Base-excision repair and beyond —A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015Science China Life Sciences20163
38ASXL2 Is Required for Normal Hematopoiesis and Loss of asxl2 Leads to Myeloid Malignancies in MiceBlood20162
39PDE4B Proposed as a High Myopia Susceptibility Gene in Chinese PopulationFrontiers in Genetics20212
40Machine-Learning Model for Resistance/Relapse Prediction in Immune Thrombocytopenia Using Gut Microbiota and Function SignaturesBlood20211
41Essential Role of c-MYC for Natural Killer Cell Development, Proliferation and Anti-Tumor ActivityBlood20170
42Myc Regulates the Development and Anti-Tumor Immunity of Natural Killer CellsBlood20180
43Outcome and Genomic Characteristics of Non-Down Syndrome Acute Megakaryoblastic Leukemia in Children Treated with Low-Dose Chemotherapy for Induction RemissionBlood20190
44Comparable Leukemic Cells Reduction but Improved Normal Hematopoietic Regeneration with G-CSF Priming Plus Low Dose Chemotherapy Regimen Relative to Standard Chemotherapy in AML Mice ModelBlood20190
45Empowering host immunity by kinase-targeting in LSCBlood Science20200