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Top Articles

#TitleJournalYearCitations
1Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequencesNature2007661
2Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2Nature2006609
3Activated T Cell Death In Vivo Mediated by Proapoptotic Bcl-2 Family Member BimImmunity2002514
4Distinct and Overlapping Roles for E2F Family Members in Transcription, Proliferation and ApoptosisCurrent Molecular Medicine2006423
5OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammationProceedings of the National Academy of Sciences of the United States of America2018346
6Mechanisms of Conformational Change for a Replicative Hexameric Helicase of SV40 Large Tumor AntigenCell2004291
7Naturally Occurring Dicistronic Cricket Paralysis Virus RNA Is Regulated by Two Internal Ribosome Entry SitesMolecular and Cellular Biology2000289
8Fission yeast Taz1 protein is required for meiotic telomere clustering and recombinationNature1998267
9Flexibility of single-stranded DNA: use of gapped duplex helices to determine the persistence lengths of Poly(dT) and Poly(dA) 1 1Edited by B. HonigJournal of Molecular Biology1999236
10Both subunits of U2AF recognize the 3′ splice site in Caenorhabditis elegansNature1999229
11Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cellsOncogene2003216
12Cr2, a Candidate Gene in the Murine Sle1c Lupus Susceptibility Locus, Encodes a Dysfunctional ProteinImmunity2001214
13Ctr9, Rtf1, and Leo1 Are Components of the Paf1/RNA Polymerase II ComplexMolecular and Cellular Biology2002209
14Clinical involvement and protein expression in individuals with theFMR1 premutation2000202
15Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 PatientsJournal of Proteome Research2020189
16Structural Characterization of the SARS-Coronavirus Spike S Fusion Protein CoreJournal of Biological Chemistry2004182
17The DIX domain targets dishevelled to actin stress fibres and vesicular membranesNature2002180
18Neuronal migration is retarded in mice lacking the tissue plasminogen activator geneProceedings of the National Academy of Sciences of the United States of America1999176
19Pre-mRNA splicing is a determinant of histone H3K36 methylationProceedings of the National Academy of Sciences of the United States of America2011175
20PyCogent: a toolkit for making sense from sequenceGenome Biology2007170
21Gene clusters and polycistronic transcription in eukaryotesBioEssays1998168
22The Fission Yeast Taz1 Protein Protects Chromosomes from Ku-Dependent End-to-End FusionsMolecular Cell2001164
23Peptide Nanoparticles as Novel Immunogens: Design and Analysis of a Prototypic Severe Acute Respiratory Syndrome VaccineChemical Biology and Drug Design2009158
24Serum Proteomics in COVID-19 Patients: Altered Coagulation and Complement Status as a Function of IL-6 LevelJournal of Proteome Research2020155
25Fragile X males with unmethylated, full mutation trinucleotide repeat expansions have elevated levels ofFMR1 messenger RNAAmerican Journal of Medical Genetics Part A2000154
26Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteinsNature Structural and Molecular Biology2007154
27The χψ Subunits of DNA Polymerase III Holoenzyme Bind to Single-stranded DNA-binding Protein (SSB) and Facilitate Replication of an SSB-coated TemplateJournal of Biological Chemistry1998151
28Transcriptional Activators Are Dispensable for Transcription in the Absence of Spt6-Mediated Chromatin Reassembly of Promoter RegionsMolecular Cell2006150
29Chaperone-mediated autophagy sustains haematopoietic stem-cell functionNature2021145
30Cdc7p-Dbf4p becomes famous in the cell cycleJournal of Cell Science2000139
31Adenoviral-mediated gene transfer in lymphocytesProceedings of the National Academy of Sciences of the United States of America1998134
32Chromosomal replicases as asymmetric dimers: studies of subunit arrangement and functional consequencesMolecular Microbiology2003133
33Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathwaysProceedings of the National Academy of Sciences of the United States of America2003133
34Essential Role of GATA3 for the Maintenance of Type 2 Helper T (Th2) Cytokine Production and Chromatin Remodeling at the Th2 Cytokine Gene LociJournal of Biological Chemistry2004133
35MutationFinder: a high-performance system for extracting point mutation mentions from textBioinformatics2007132
36Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storageHaematologica2018131
37The link between mRNA processing and transcription: communication works both waysExperimental Cell Research2004127
38Chromatin assemblyFEBS Journal2002125
39Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cellsProceedings of the National Academy of Sciences of the United States of America2004120
40Mice Lacking tPA, uPA, or Plasminogen Genes Showed Delayed Functional Recovery after Sciatic Nerve CrushJournal of Neuroscience2001119
41Histone H3K4me3 Binding Is Required for the DNA Repair and Apoptotic Activities of ING1 Tumor SuppressorJournal of Molecular Biology2008115
42Contribution of Translational and Rotational Motions to Molecular Association in Aqueous SolutionBiophysical Journal2001111
43E2F1 and E2F2 Determine Thresholds for Antigen-Induced T-Cell Proliferation and Suppress TumorigenesisMolecular and Cellular Biology2001100
44Gene Amplification Is a Mechanism of Six1 Overexpression in Breast CancerCancer Research2005100
45AltitudeOmics: Red Blood Cell Metabolic Adaptation to High Altitude HypoxiaJournal of Proteome Research201698
46Dense Core Vesicle Dynamics in Caenorhabditis elegans Neurons and the Role of Kinesin UNC-104Traffic200497
47Stabilizing and Destabilizing Clusters in the Hydrophobic Core of Long Two-stranded α-Helical Coiled-coilsJournal of Biological Chemistry200496
48A Bipartite Polymerase–Processivity Factor Interaction: Only the Internal β Binding Site of the α Subunit is Required for Processive Replication by the DNA Polymerase III HoloenzymeJournal of Molecular Biology200596
49Comparative mitochondrial genomics of snakes: extraordinary substitution rate dynamics and functionality of the duplicate control regionBMC Evolutionary Biology200796
50Absence of Tissue Plasminogen Activator Gene or Activity Impairs Mouse Cerebellar Motor LearningJournal of Neuroscience200395