| # | Title | Journal | Year | Citations |
|---|
| 1 | The genome sequence of the filamentous fungus Neurospora crassa | Nature | 2003 | 1,528 |
| 2 | The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog | Nature | 1996 | 1,065 |
| 3 | A method for the comprehensive proteomic analysis of membrane proteins | Nature Biotechnology | 2003 | 661 |
| 4 | Sodium channel Nav1.6 is localized at nodes of Ranvier, dendrites, and synapses | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 586 |
| 5 | Lessons from the Genome Sequence of Neurospora crassa : Tracing the Path from Genomic Blueprint to Multicellular Organism | Microbiology and Molecular Biology Reviews | 2004 | 572 |
| 6 | The Drosophila smoothened Gene Encodes a Seven-Pass Membrane Protein, a Putative Receptor for the Hedgehog Signal | Cell | 1996 | 568 |
| 7 | Selective modulation of protein kinase C-Θ during T-cell activation | Nature | 1997 | 532 |
| 8 | Vagal immune-to-brain communication: a visceral chemosensory pathway | Autonomic Neuroscience: Basic and Clinical | 2000 | 438 |
| 9 | Solitary chemoreceptor cells in the nasal cavity serve as sentinels of respiration | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 388 |
| 10 | Compact Myelin Dictates the Differential Targeting of Two Sodium Channel Isoforms in the Same Axon | Neuron | 2001 | 373 |
| 11 | Interaction of Muscle and Brain Sodium Channels with Multiple Members of the Syntrophin Family of Dystrophin-Associated Proteins | Journal of Neuroscience | 1998 | 340 |
| 12 | A New Family of Plant Antifungal Proteins | Molecular Plant-Microbe Interactions | 1991 | 312 |
| 13 | Zeamatin, an antifungal protein from maize with membrane-permeabilizing activity | Journal of General Microbiology | 1990 | 287 |
| 14 | Vagal Paraganglia Bind Biotinylated Interleukin-1 Receptor Antagonist: A Possible Mechanism for Immune-to-Brain Communication | Brain Research Bulletin | 1997 | 281 |
| 15 | Correlation between Olfactory Receptor Cell Type and Function in the Channel Catfish | Journal of Neuroscience | 2003 | 236 |
| 16 | Thaumatin-like pathogenesis-related proteins are antifungal | Plant Science | 1992 | 231 |
| 17 | A novel, abundant sodium channel expressed in neurons and glia | Journal of Neuroscience | 1995 | 220 |
| 18 | Ribonucleoprotein particles with LINE-1 RNA in mouse embryonal carcinoma cells. | Molecular and Cellular Biology | 1991 | 217 |
| 19 | Proteomics reveal a link between the endoplasmic reticulum and lipid secretory mechanisms in mammary epithelial cells | Electrophoresis | 2000 | 206 |
| 20 | Whole recombinant yeast vaccine activates dendritic cells and elicits protective cell-mediated immunity | Nature Medicine | 2001 | 198 |
| 21 | Plant and Bacterial Chitinases Differ in Antifungal Activity | Microbiology (United Kingdom) | 1988 | 180 |
| 22 | Tightly regulated, developmentally specific expression of the first open reading frame from LINE-1 during mouse embryogenesis. | Proceedings of the National Academy of Sciences of the United States of America | 1995 | 152 |
| 23 | A distinct vesicle population targets membranes and pore complexes to the nuclear envelope in Xenopus eggs. | Journal of Cell Biology | 1991 | 151 |
| 24 | Alpha‐1‐antitrypsin inhibits human immunodeficiency virus type 1 | FASEB Journal | 2001 | 149 |
| 25 | Central role for differential gene expression in mammalian hibernation. | Proceedings of the National Academy of Sciences of the United States of America | 1992 | 143 |
| 26 | Olfactory Fingerprints for Major Histocompatibility Complex-Determined Body Odors | Journal of Neuroscience | 2001 | 140 |
| 27 | Ribonucleoprotein particles with LINE-1 RNA in mouse embryonal carcinoma cells | Molecular and Cellular Biology | 1991 | 137 |
| 28 | Phyletic Distribution of Crypt-Type Olfactory Receptor Neurons in Fishes | Brain, Behavior and Evolution | 2000 | 123 |
| 29 | Disruption of sonic hedgehog signaling alters growth and patterning of lingual taste papillae | Developmental Biology | 2003 | 122 |
| 30 | Distinct pathways for autocrine and paracrine Wingless signalling inDrosophila embryos | Nature | 1994 | 121 |
| 31 | Olfactory Fingerprints for Major Histocompatibility Complex-Determined Body Odors II: Relationship among Odor Maps, Genetics, Odor Composition, and Behavior | Journal of Neuroscience | 2002 | 111 |
| 32 | Alternatively spliced sodium channel transcripts in brain and muscle | Journal of Neuroscience | 1992 | 110 |
| 33 | Identification of a Functional Interaction between the Transmembrane Protein Smoothened and the Kinesin-Related Protein Costal2 | Current Biology | 2003 | 109 |
| 34 | Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 108 |
| 35 | Programmed Cell Death in Developing Grafts of Fetal Substantia Nigra | Experimental Neurology | 1994 | 106 |
| 36 | Expression ofSonic hedgehog,Patched, andGli1 in developing taste papillae of the mouse | | 1999 | 106 |
| 37 | Expression and distribution of voltage-gated sodium channels in the cerebellum | Cerebellum | 2003 | 106 |
| 38 | 6-Hydroxydopamine induces the loss of the dopaminergic phenotype in substantia nigra neurons of the rat | Experimental Brain Research | 1996 | 103 |
| 39 | Immunolocalization of sodium channel isoform NaCh6 in the nervous system | | 2000 | 103 |
| 40 | Developmental and regional expression of sodium channel isoform NaCh6 in the rat central nervous system | Journal of Comparative Neurology | 2000 | 100 |
| 41 | Translational repression of aC. elegansNotch mRNA by the STAR/KH domain protein GLD-1 | Development (Cambridge) | 2003 | 98 |
| 42 | GMx33: a novel family of trans-Golgi proteins identified by proteomics | Traffic | 2000 | 97 |
| 43 | Cilofungin (LY121019) inhibits Candida albicans (1-3)-beta-D-glucan synthase activity | Antimicrobial Agents and Chemotherapy | 1988 | 86 |
| 44 | Rabs, Rips, FIPs, and Endocytic Membrane Traffic | Scientific World Journal, The | 2003 | 77 |
| 45 | Proteomic Analysis of Two Functional States of the Golgi Complex in Mammary Epithelial Cells | Traffic | 2000 | 76 |
| 46 | Formation of Mutually Exclusive Rab11 Complexes with Members of the Family of Rab11-interacting Proteins Regulates Rab11 Endocytic Targeting and Function | Journal of Biological Chemistry | 2002 | 72 |
| 47 | Gustatory control of feeding behavior in goldfish | Physiology and Behavior | 1995 | 71 |
| 48 | How do patch clamp seals form? A lipid bleb model | Pflugers Archiv European Journal of Physiology | 1990 | 67 |
| 49 | Morphogenesis and Dynamics of the Yeast Golgi Apparatus | Traffic | 2000 | 64 |
| 50 | cDNA sequence and differential expression of the mouse Ca2+/calmodulin-dependent protein kinase IV gene | FEBS Letters | 1991 | 62 |
