| # | Title | Journal | Year | Citations |
|---|
| 1 | Acute-Phase Proteins and Other Systemic Responses to Inflammation | New England Journal of Medicine | 1999 | 5,677 |
| 2 | The staphylococcal enterotoxins and their relatives | Science | 1990 | 1,875 |
| 3 | Proinflammatory Cytokines | Chest | 2000 | 1,692 |
| 4 | Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura | Nature | 2001 | 1,623 |
| 5 | Human bone marrow colony growth in agar-gel | Journal of Cellular Physiology | 1970 | 1,270 |
| 6 | Cell-Surface Calreticulin Initiates Clearance of Viable or Apoptotic Cells through trans-Activation of LRP on the Phagocyte | Cell | 2005 | 1,225 |
| 7 | Acute Renal Failure and Sepsis | New England Journal of Medicine | 2004 | 1,139 |
| 8 | Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes | Nature Genetics | 2018 | 1,124 |
| 9 | Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity. | Journal of Clinical Investigation | 1997 | 996 |
| 10 | Inhibition of VEGF receptors causes lung cell apoptosis and emphysema | Journal of Clinical Investigation | 2000 | 979 |
| 11 | Autosomal Dominant Polycystic Kidney Disease | New England Journal of Medicine | 1993 | 933 |
| 12 | INTERLEUKIN-1 RECEPTOR ANTAGONIST: Role in Biology | Annual Review of Immunology | 1998 | 933 |
| 13 | Aging, Habitual Exercise, and Dynamic Arterial Compliance | Circulation | 2000 | 933 |
| 14 | Lipoprotein Lipase | New England Journal of Medicine | 1989 | 908 |
| 15 | Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis | Arthritis and Rheumatism | 1990 | 903 |
| 16 | Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat | Nature Genetics | 2000 | 811 |
| 17 | Control of Homeostasis of CD8+ Memory T Cells by Opposing Cytokines | Science | 2000 | 776 |
| 18 | Phlorizin: a review | Diabetes/Metabolism Research and Reviews | 2005 | 772 |
| 19 | Cotransplantation of HLA-Identical Sibling Culture-Expanded Mesenchymal Stem Cells and Hematopoietic Stem Cells in Hematologic Malignancy Patients | Biology of Blood and Marrow Transplantation | 2005 | 745 |
| 20 | IL-18: A TH1 -inducing, proinflammatory cytokine and new member of the IL-1 family | Journal of Allergy and Clinical Immunology | 1999 | 740 |
| 21 | Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and strokes | Kidney International | 2002 | 727 |
| 22 | Report of the ISHLT Working Group on Primary Lung Graft Dysfunction Part II: Definition. A Consensus Statement of the International Society for Heart and Lung Transplantation | Journal of Heart and Lung Transplantation | 2005 | 724 |
| 23 | Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death‐dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension | FASEB Journal | 2001 | 721 |
| 24 | Changes in Clinical and Physiologic Variables Predict Survival in Idiopathic Pulmonary Fibrosis | American Journal of Respiratory and Critical Care Medicine | 2003 | 664 |
| 25 | Sensitivity of serum methylmalonic acid and total homocysteine determinations for diagnosing cobalamin and folate deficiencies | American Journal of Medicine | 1994 | 651 |
| 26 | By Binding SIRPα or Calreticulin/CD91, Lung Collectins Act as Dual Function Surveillance Molecules to Suppress or Enhance Inflammation | Cell | 2003 | 637 |
| 27 | Leptin in the regulation of immunity, inflammation, and hematopoiesis | Journal of Leukocyte Biology | 2000 | 630 |
| 28 | Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes | Nature | 1999 | 606 |
| 29 | Leptin in the regulation of immunity, inflammation, and hematopoiesis | Journal of Leukocyte Biology | 2002 | 600 |
| 30 | RESPIRATORY VIRUS IMMUNIZATION | American Journal of Epidemiology | 1969 | 585 |
| 31 | Nuclear receptor coactivators and corepressors. | Molecular Endocrinology | 1996 | 582 |
| 32 | Cellular Mechanisms for Insulin Resistance in Normal Pregnancy and Gestational Diabetes | Diabetes Care | 2007 | 572 |
| 33 | Genes encoding putative effector proteins of the type III secretion system ofSalmonellapathogenicity island 2 are required for bacterial virulence and proliferation in macrophages | Molecular Microbiology | 1998 | 571 |
| 34 | Epidemiology of Vitiligo and Associated Autoimmune Diseases in Caucasian Probands and Their Families | Pigment Cell & Melanoma Research | 2003 | 563 |
| 35 | Complement C3 Activation Is Required for Antiphospholipid Antibody-induced Fetal Loss | Journal of Experimental Medicine | 2002 | 557 |
| 36 | Molecular characterization of human prostate carcinoma cell lines | Prostate | 2003 | 555 |
| 37 | Interleukin 1 receptor antagonist. A new member of the interleukin 1 family. | Journal of Clinical Investigation | 1991 | 546 |
| 38 | Early Pulmonary Inflammation in Infants with Cystic Fibrosis | American Journal of Respiratory and Critical Care Medicine | 1995 | 545 |
| 39 | Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist. | Journal of Clinical Investigation | 1990 | 526 |
| 40 | Interleukin-32 | Immunity | 2005 | 520 |
| 41 | Salmonella Pathogenicity Island 2-Dependent Evasion of the Phagocyte NADPH Oxidase | Science | 2000 | 513 |
| 42 | Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells. | Journal of Clinical Investigation | 1998 | 501 |
| 43 | Phosphorylation and activation of a high molecular weight form of phospholipase A2 by p42 microtubule-associated protein 2 kinase and protein kinase C. | Journal of Biological Chemistry | 1993 | 494 |
| 44 | Clinical features of vocal cord dysfunction. | American Journal of Respiratory and Critical Care Medicine | 1995 | 488 |
| 45 | Antimicrobial Actions of the Nadph Phagocyte Oxidase and Inducible Nitric Oxide Synthase in Experimental Salmonellosis. I. Effects on Microbial Killing by Activated Peritoneal Macrophages in Vitro | Journal of Experimental Medicine | 2000 | 488 |
| 46 | Reduction in the Incidence of Acute Myocardial Infarction Associated With a Citywide Smoking Ordinance | Circulation | 2006 | 480 |
| 47 | Interleukin-1 Receptor Antagonist | Advances in Immunology | 1993 | 475 |
| 48 | Identification of a central role for complement in osteoarthritis | Nature Medicine | 2011 | 470 |
| 49 | Consensus Statement on Chronic and Subacute High Altitude Diseases | High Altitude Medicine and Biology | 2005 | 467 |
| 50 | Excessive Antibiotic Use for Acute Respiratory Infections in the United States | Clinical Infectious Diseases | 2001 | 465 |
