Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations | Cancer Discovery | 2014 | 310 |
SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution | PLoS Computational Biology | 2014 | 301 |
The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramers | Cancer Cell | 2014 | 285 |
Regulation of hematopoietic stem cells by bone marrow stromal cells | Trends in Immunology | 2014 | 187 |
Pretherapy metabolic tumour volume is an independent predictor of outcome in patients with diffuse large B-cell lymphoma | European Journal of Nuclear Medicine and Molecular Imaging | 2014 | 135 |
Molecular and cellular heterogeneity: the hallmark of glioblastoma | Neurosurgical Focus | 2014 | 110 |
Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing | PLoS Genetics | 2014 | 94 |
Impact of 18F-fluoride PET in patients with known prostate cancer: initial results from the National Oncologic PET Registry | Journal of Nuclear Medicine | 2014 | 75 |
Masitinib in advanced gastrointestinal stromal tumor (GIST) after failure of imatinib: a randomized controlled open-label trial | Annals of Oncology | 2014 | 54 |
Clonal architectures and driver mutations in metastatic melanomas | PLoS ONE | 2014 | 53 |
ARF tumor suppression in the nucleolus | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2014 | 51 |
Elevated DDX21 regulates c-Jun activity and rRNA processing in human breast cancers | Breast Cancer Research | 2014 | 40 |
ARF and p53 coordinate tumor suppression of an oncogenic IFN-β-STAT1-ISG15 signaling axis | Cell Reports | 2014 | 38 |
Evaluation of participant recruitment methods to a rare disease online registry | American Journal of Medical Genetics, Part A | 2014 | 31 |
Diabetes and pancreatic cancer survival: a prospective cohort-based study | British Journal of Cancer | 2014 | 29 |
Novel treatment option for MUC16-positive malignancies with the targeted TRAIL-based fusion protein Meso-TR3 | BMC Cancer | 2014 | 23 |
New concepts in breast cancer genomics and genetics | Breast Cancer Research | 2014 | 23 |
Genomic tools in acute myeloid leukemia: From the bench to the bedside | Cancer | 2014 | 21 |
High frequency strand slippage mutations in CTCF in MSI-positive endometrial cancers | Human Mutation | 2014 | 20 |
Conjugation to a SMAC mimetic potentiates sigma-2 ligand induced tumor cell death in ovarian cancer | Molecular Cancer | 2014 | 20 |
Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice | Blood | 2014 | 18 |
Small molecule inhibitors in acute myeloid leukemia: from the bench to the clinic | Expert Review of Hematology | 2014 | 16 |
Patterns of care, predictors, and outcomes of chemotherapy in elderly women with early-stage uterine carcinosarcoma: a population-based analysis | Gynecologic Oncology | 2014 | 15 |
The ARF tumor-suppressor controls Drosha translation to prevent Ras-driven transformation | Oncogene | 2014 | 12 |
A phase I study of pegylated liposomal doxorubicin and temsirolimus in patients with refractory solid malignancies | Cancer Chemotherapy and Pharmacology | 2014 | 4 |