| # | Title | Journal | Year | Citations |
|---|
| 1 | Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing | Nature Biotechnology | 2013 | 1,785 |
| 2 | The HER-2 Receptor and Breast Cancer: Ten Years of Targeted Anti–HER-2 Therapy and Personalized Medicine | Oncologist | 2009 | 986 |
| 3 | Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation | Hepatology | 2000 | 945 |
| 4 | The HER‐2/ neu Oncogene in Breast Cancer: Prognostic Factor, Predictive Factor, and Target for Therapy | Stem Cells | 1998 | 704 |
| 5 | The HER‐2/ neu Gene and Protein in Breast Cancer 2003: Biomarker and Target of Therapy | Oncologist | 2003 | 561 |
| 6 | Inflammatory Responses to Biomaterials | American Journal of Clinical Pathology | 1995 | 427 |
| 7 | New Routes to Targeted Therapy of Intrahepatic Cholangiocarcinomas Revealed by Next-Generation Sequencing | Oncologist | 2014 | 371 |
| 8 | Heterogeneity and plasticity of hepatocyte lineage cells | Hepatology | 2001 | 350 |
| 9 | The HER‐2/ neu Oncogene in Breast Cancer: Prognostic Factor, Predictive Factor, and Target for Therapy | Oncologist | 1998 | 297 |
| 10 | Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: regulation by ultraviolet B | Biochimica Et Biophysica Acta - Molecular Cell Research | 1996 | 290 |
| 11 | Targeted Therapy in Breast Cancer | Molecular and Cellular Proteomics | 2004 | 263 |
| 12 | Loss of Expression of the PTEN Gene Protein Product Is Associated with Poor Outcome in Breast Cancer | Modern Pathology | 2001 | 240 |
| 13 | The HER-2/neuOncogene in Tumors of the Gastrointestinal Tract | Cancer Investigation | 2001 | 236 |
| 14 | Commercialized Multigene Predictors of Clinical Outcome for Breast Cancer | Oncologist | 2008 | 235 |
| 15 | Prostate-specific membrane antigen expression in the neovasculature of gastric and colorectal cancers | Human Pathology | 2009 | 209 |
| 16 | Chemical camouflage of antigenic determinants: Stealth erythrocytes | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 199 |
| 17 | Increased expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinases 1 and 2 correlate with poor prognostic variables in renal cell carcinoma | Clinical Cancer Research | 2001 | 197 |
| 18 | Melanogenesis During the Anagen-Catagen-Telogen Transformation of the Murine Hair Cycle | Journal of Investigative Dermatology | 1994 | 190 |
| 19 | ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin. | Journal of Clinical Endocrinology and Metabolism | 1996 | 180 |
| 20 | The HER-2/neu oncogene: prognostic factor, predictive factor and target for therapy | Seminars in Cancer Biology | 1999 | 156 |
| 21 | Whole Cancer Genome Sequencing by Next-Generation Methods | American Journal of Clinical Pathology | 2011 | 155 |
| 22 | Proopiomelanocortin, corticotropin releasing hormone and corticotropin releasing hormone receptor genes are expressed in human skin | FEBS Letters | 1995 | 153 |
| 23 | Activation of Human T Cells by Major Histocompatability Complex Class II Expressing Neutrophils: Proliferation in the Presence of Superantigen, But Not Tetanus Toxoid | Blood | 1997 | 136 |
| 24 | Loss of claudins-1 and -7 and expression of claudins-3 and -4 correlate with prognostic variables in prostatic adenocarcinomas | Human Pathology | 2007 | 135 |
| 25 | Comparison of liver progenitor cells in human atypical ductular reactions with those seen in experimental models of liver injury | Hepatology | 1998 | 132 |
| 26 | Expression of Nuclear Factor-κB and IκBα Proteins in Prostatic Adenocarcinomas | Clinical Cancer Research | 2004 | 126 |
| 27 | Relapsed Classic E-Cadherin (CDH1)–Mutated Invasive Lobular Breast Cancer Shows a High Frequency of HER2 (ERBB2) Gene Mutations | Clinical Cancer Research | 2013 | 122 |
| 28 | Advanced urothelial carcinoma: next-generation sequencing reveals diverse genomic alterations and targets of therapy | Modern Pathology | 2014 | 122 |
| 29 | A High Frequency of Activating Extracellular Domain ERBB2 (HER2) Mutation in Micropapillary Urothelial Carcinoma | Clinical Cancer Research | 2014 | 120 |
| 30 | Metabolism of Serotonin to N-Acetylserotonin, Melatonin, and 5-Methoxytryptamine in Hamster Skin Culture | Journal of Biological Chemistry | 1996 | 119 |
| 31 | Melanoma Resistance: A Bright Future for Academicians and a Challenge for Patient Advocates | Mayo Clinic Proceedings | 2014 | 113 |
| 32 | POTENTIAL MECHANISM OF SKIN RESPONSE TO STRESS | International Journal of Dermatology | 1996 | 112 |
| 33 | Prognostic significance of HER-2/neu gene amplification status by fluorescence in Situ hybridization of prostate carcinoma | | 1997 | 112 |
| 34 | The dorsal root ganglion in Friedreich’s ataxia | Acta Neuropathologica | 2009 | 112 |
| 35 | The HER-2/neu Oncogene in Breast Cancer: Prognostic Factor, Predictive Factor, and Target for Therapy | Oncologist | 1998 | 112 |
| 36 | Decreased expression of catenins (? and ?), p120 CTN, and E-cadherin cell adhesion proteins and E-cadherin gene promoter methylation in prostatic adenocarcinomas | Cancer | 2001 | 110 |
| 37 | Clinical next‐generation sequencing successfully applied to fine‐needle aspirations of pulmonary and pancreatic neoplasms | Cancer Cytopathology | 2013 | 110 |
| 38 | Activation of nuclear factor-κB in human prostate carcinogenesis and association to biochemical relapse | British Journal of Cancer | 2005 | 109 |
| 39 | Update on hepatocellular carcinoma: Pathologists’ review | World Journal of Gastroenterology | 2019 | 100 |
| 40 | Profiling of 149 Salivary Duct Carcinomas, Carcinoma Ex Pleomorphic Adenomas, and Adenocarcinomas, Not Otherwise Specified Reveals Actionable Genomic Alterations | Clinical Cancer Research | 2016 | 99 |
| 41 | The expression of proopiomelanocortin (POMC) and of corticotropin releasing hormone receptor (CRH-R) genes in mouse skin | Biochimica Et Biophysica Acta - General Subjects | 1996 | 92 |
| 42 | Cellular origin of hepatocellular carcinomas | Seminars in Cell and Developmental Biology | 2002 | 90 |
| 43 | Characterization of Clinical Cases of Collecting Duct Carcinoma of the Kidney Assessed by Comprehensive Genomic Profiling | European Urology | 2016 | 90 |
| 44 | HER-2/neu gene amplification status in prostate cancer by fluorescence in situ hybridization | Human Pathology | 1997 | 89 |
| 45 | Circulating and Disseminated Tumor Cells in the Management of Breast Cancer | American Journal of Clinical Pathology | 2009 | 89 |
| 46 | Primary hepatic leiomyosarcoma in a child with the acquired immunodeficiency syndrome | Human Pathology | 1992 | 87 |
| 47 | Characterization of Clinical Cases of Advanced Papillary Renal Cell Carcinoma via Comprehensive Genomic Profiling | European Urology | 2018 | 87 |
| 48 | Localized lymphedema (elephantiasis): a case series and review of the literature | Journal of Cutaneous Pathology | 2009 | 86 |
| 49 | The prognostic significance of p34cdc2 and cyclin D1 protein expression in prostate adenocarcinoma | Cancer | 1997 | 85 |
| 50 | Comprehensive genomic profiling of epithelial ovarian cancer by next generation sequencing-based diagnostic assay reveals new routes to targeted therapies | Gynecologic Oncology | 2013 | 85 |
