| # | Title | Journal | Year | Citations |
|---|
| 1 | Current and future pharmacological therapies for NAFLD/NASH | Journal of Gastroenterology | 2018 | 490 |
| 2 | Dietary phytochemicals and cancer chemoprevention: a review of the clinical evidence | Oncotarget | 2016 | 309 |
| 3 | Psychometric Validation of the Bangla Fear of COVID-19 Scale: Confirmatory Factor Analysis and Rasch Analysis | International Journal of Mental Health and Addiction | 2022 | 284 |
| 4 | Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD: an individual patient data meta-analysis | Gut | 2022 | 195 |
| 5 | Vitamin E has a beneficial effect on nonalcoholic fatty liver disease: A meta-analysis of randomized controlled trials | Nutrition | 2015 | 156 |
| 6 | Gene therapy for mitochondrial disease by delivering restriction endonucleaseSmaI into mitochondria | Journal of Biomedical Science | 2002 | 151 |
| 7 | Nonneural Nuclear Inclusions of Androgen Receptor Protein in Spinal and Bulbar Muscular Atrophy | American Journal of Pathology | 1998 | 127 |
| 8 | Effects of Pemafibrate, a Novel Selective PPARα Modulator, on Lipid and Glucose Metabolism in Patients With Type 2 Diabetes and Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial | Diabetes Care | 2018 | 122 |
| 9 | Therapeutic Neovascularization Using Cord Blood-Derived Endothelial Progenitor Cells for Diabetic Neuropathy | Diabetes | 2005 | 118 |
| 10 | Gene Therapy for Mitochondrial Disease by Delivering Restriction Endonuclease SmaI into Mitochondria | Journal of Biomedical Science | 2002 | 106 |
| 11 | Causes of death in Japanese patients with diabetes based on the results of a survey of 45,708 cases during 2001–2010: Report of the Committee on Causes of Death in Diabetes Mellitus | Journal of Diabetes Investigation | 2017 | 95 |
| 12 | Transient responses of inflammatory cytokines in acute stress | Biological Psychology | 2009 | 85 |
| 13 | Palmitate-induced lipotoxicity is crucial for the pathogenesis of nonalcoholic fatty liver disease in cooperation with gut-derived endotoxin | Scientific Reports | 2018 | 85 |
| 14 | Effect of luseogliflozin on hepatic fat content in type 2 diabetes patients with non‐alcoholic fatty liver disease: A prospective, single‐arm trial (LEAD trial) | Hepatology Research | 2019 | 85 |
| 15 | A minipig model of high‐fat/high‐sucrose diet‐induced diabetes and atherosclerosis | International Journal of Experimental Pathology | 2004 | 79 |
| 16 | The novel cutoff points for the FIB4 index categorized by age increase the diagnostic accuracy in NAFLD: a multi-center study | Journal of Gastroenterology | 2018 | 68 |
| 17 | HOMA‐IR: An independent predictor of advanced liver fibrosis in nondiabetic non‐alcoholic fatty liver disease | Journal of Gastroenterology and Hepatology (Australia) | 2019 | 67 |
| 18 | Reduced NGF secretion by Schwann cells under the high glucose condition decreases neurite outgrowth of DRG neurons | Experimental Neurology | 2008 | 66 |
| 19 | Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study | BMC Gastroenterology | 2017 | 65 |
| 20 | Efficacy and safety of canagliflozin in type 2 diabetes mellitus patients with biopsy-proven nonalcoholic steatohepatitis classified as stage 1–3 fibrosis | Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy | 2018 | 60 |
| 21 | Ezetimibe for the treatment of non‐alcoholic fatty liver disease: A meta‐analysis | Hepatology Research | 2017 | 58 |
| 22 | The Asn505 mutation of the c-MPL gene, which causes familial essential thrombocythemia, induces autonomous homodimerization of the c-Mpl protein due to strong amino acid polarity | Blood | 2009 | 57 |
| 23 | Phase 3 drug pipelines in the treatment of non‐alcoholic steatohepatitis | Hepatology Research | 2019 | 54 |
| 24 | Metformin prevents methylglyoxal-induced apoptosis of mouse Schwann cells | Biochemical and Biophysical Research Communications | 2007 | 53 |
| 25 | Novel antidiabetic medications for non‐alcoholic fatty liver disease with type 2 diabetes mellitus | Hepatology Research | 2017 | 53 |
| 26 | A functional polymorphism in the NKG2D gene modulates NK-cell cytotoxicity and is associated with susceptibility to Human Papilloma Virus-related cancers | Scientific Reports | 2016 | 52 |
| 27 | Impact of age on outcomes of allogeneic hematopoietic stem cell transplantation with reduced intensity conditioning in elderly patients with acute myeloid leukemia | American Journal of Hematology | 2016 | 49 |
| 28 | Causes of death in Japanese patients with diabetes based on the results of a survey of 45,708 cases during 2001–2010: report of Committee on Causes of Death in Diabetes Mellitus | Diabetology International | 2017 | 49 |
| 29 | Angiotensin II type 1 receptor antagonist prevents hepatic carcinoma in rats with nonalcoholic steatohepatitis | Journal of Gastroenterology | 2013 | 48 |
| 30 | Role of V 14+ NKT cells in the development of Hepatitis B virus-specific CTL: activation of V 14+ NKT cells promotes the breakage of CTL tolerance | International Immunology | 2008 | 46 |
| 31 | Antidiabetic Therapy in the Treatment of Nonalcoholic Steatohepatitis | International Journal of Molecular Sciences | 2020 | 42 |
| 32 | Implication of Altered Redox Regulation by Antioxidant Enzymes in the Increased Plasma Pentosidine, an Advanced Glycation End Product, in Uremia | Biochemical and Biophysical Research Communications | 1998 | 37 |
| 33 | A Protein Toxin from the Sea Anemone Phyllodiscus semoni Targets the Kidney and Causes a Severe Renal Injury with Predominant Glomerular Endothelial Damage | American Journal of Pathology | 2007 | 37 |
| 34 | Physiological effects of epigallocatechin-3-gallate (EGCG) on energy expenditure for prospective fat oxidation in humans: A systematic review and meta-analysis | Journal of Nutritional Biochemistry | 2017 | 37 |
| 35 | Efficacy and safety of pemafibrate in people with type 2 diabetes and elevated triglyceride levels: 52‐week data from the PROVIDE study | Diabetes, Obesity and Metabolism | 2019 | 35 |
| 36 | Outcome of Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia Patients with Central Nervous System Involvement | Biology of Blood and Marrow Transplantation | 2014 | 34 |
| 37 | High Levels of Complement C3a Receptor in the Glomeruli in Lupus Nephritis | American Journal of Kidney Diseases | 2007 | 33 |
| 38 | Conditioned media from dental pulp stem cells improved diabetic polyneuropathy through anti‐inflammatory, neuroprotective and angiogenic actions: Cell‐free regenerative medicine for diabetic polyneuropathy | Journal of Diabetes Investigation | 2019 | 33 |
| 39 | Inhibitory effect of oxytocin on accelerated colonic motility induced by water‐avoidance stress in rats | Neurogastroenterology and Motility | 2009 | 32 |
| 40 | The Improvement of the Hepatic Histological Findings in a Patient with Non-alcoholic Steatohepatitis with Type 2 Diabetes after the Administration of the Sodium-glucose Cotransporter 2 Inhibitor Ipragliflozin | Internal Medicine | 2017 | 32 |
| 41 | A Data Mining-based Prognostic Algorithm for NAFLD-related Hepatoma Patients: A Nationwide Study by the Japan Study Group of NAFLD | Scientific Reports | 2018 | 32 |
| 42 | Clinical Outcomes in Biopsy-Proven Nonalcoholic Fatty Liver Disease Patients: A Multicenter Registry-based Cohort Study | Clinical Gastroenterology and Hepatology | 2023 | 30 |
| 43 | Multiple myeloma with high-risk cytogenetics and its treatment approach | International Journal of Hematology | 2022 | 30 |
| 44 | Modulatory effects of calcitonin gene-related peptide and substance P on human cholinergic sweat secretion | Clinical Autonomic Research | 1994 | 29 |
| 45 | Current and new pharmacotherapy options for non-alcoholic steatohepatitis | Expert Opinion on Pharmacotherapy | 2020 | 28 |
| 46 | A simple one-step purification of human α1-proteinase inhibitor by immunoadsorbent column chromatography | Journal of Proteomics | 1981 | 27 |
| 47 | Multiple myeloma oncogene 1 (MUM1)/interferon regulatory factor 4 (IRF4) upregulates monokine induced by interferon-γ (MIG) gene expression in B-cell malignancy | Leukemia | 2005 | 26 |
| 48 | Effects of green tea catechins on nonalcoholic steatohepatitis (NASH) patients | Journal of Functional Foods | 2014 | 26 |
| 49 | Genetic determinants of risk in autoimmune pulmonary alveolar proteinosis | Nature Communications | 2021 | 26 |
| 50 | Gut microbiota composition associated with hepatic fibrosis in non‐obese patients with non‐alcoholic fatty liver disease | Journal of Gastroenterology and Hepatology (Australia) | 2021 | 26 |
