| # | Title | Journal | Year | Citations |
|---|
| 1 | Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies | Science Translational Medicine | 2014 | 3,665 |
| 2 | Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. | Journal of Clinical Oncology | 1993 | 1,997 |
| 3 | Neuroblastoma: biological insights into a clinical enigma | Nature Reviews Cancer | 2003 | 1,871 |
| 4 | Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia | Science Translational Medicine | 2015 | 1,402 |
| 5 | The landscape of genomic alterations across childhood cancers | Nature | 2018 | 1,068 |
| 6 | Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy | Cancer Discovery | 2015 | 997 |
| 7 | The genetic landscape of high-risk neuroblastoma | Nature Genetics | 2013 | 990 |
| 8 | Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia | Cancer Discovery | 2016 | 811 |
| 9 | Genetic Alterations Activating Kinase and Cytokine Receptor Signaling in High-Risk Acute Lymphoblastic Leukemia | Cancer Cell | 2012 | 621 |
| 10 | CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia | Blood | 2015 | 598 |
| 11 | Molecular Biology of Neuroblastoma | Journal of Clinical Oncology | 1999 | 567 |
| 12 | Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy | Blood | 2013 | 524 |
| 13 | Ewing's sarcoma | Lancet Oncology, The | 2010 | 514 |
| 14 | Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell | Nature Medicine | 2018 | 459 |
| 15 | Posttraumatic Stress Disorder (PTSD) and Posttraumatic Stress Symptoms (PTSS) in Families of Adolescent Childhood Cancer Survivors | Journal of Pediatric Psychology | 2004 | 397 |
| 16 | Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor–modified T cells | Blood | 2014 | 396 |
| 17 | Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia | Blood | 2016 | 381 |
| 18 | Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma | Nature Genetics | 2013 | 374 |
| 19 | Posttraumatic Growth in Adolescent Survivors of Cancer and Their Mothers and Fathers | Journal of Pediatric Psychology | 2006 | 362 |
| 20 | Cytokine Release Syndrome After Chimeric Antigen Receptor T Cell Therapy for Acute Lymphoblastic Leukemia | Critical Care Medicine | 2017 | 357 |
| 21 | Secondary leukemias induced by topoisomerase-targeted drugs | Biochimica Et Biophysica Acta Gene Regulatory Mechanisms | 1998 | 353 |
| 22 | AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3 | Leukemia | 2010 | 341 |
| 23 | Utilization of special education services and educational attainment among long-term survivors of childhood cancer | Cancer | 2003 | 327 |
| 24 | CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity | Nature Communications | 2016 | 325 |
| 25 | Symptoms of Posttraumatic Stress in Young Adult Survivors of Childhood Cancer | Journal of Clinical Oncology | 2000 | 317 |
| 26 | Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia | Nature Genetics | 2010 | 308 |
| 27 | A meta-analytic review of the influence of pediatric cancer on parent and family functioning. | Journal of Family Psychology | 2007 | 306 |
| 28 | Grading of cytokine release syndrome associated with the CAR T cell therapy tisagenlecleucel | Journal of Hematology and Oncology | 2018 | 302 |
| 29 | A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor Gene | Molecular Cancer Research | 2008 | 298 |
| 30 | Revised diagnostic criteria for neurofibromatosis type 1 and Legius syndrome: an international consensus recommendation | Genetics in Medicine | 2021 | 290 |
| 31 | A social‐ecological model of readiness for transition to adult‐oriented care for adolescents and young adults with chronic health conditions | Child: Care, Health and Development | 2011 | 284 |
| 32 | Cellular kinetics of CTL019 in relapsed/refractory B-cell acute lymphoblastic leukemia and chronic lymphocytic leukemia | Blood | 2017 | 273 |
| 33 | Mg 2+ Regulates Cytotoxic Functions of NK and CD8 T Cells in Chronic EBV Infection Through NKG2D | Science | 2013 | 269 |
| 34 | X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management and outcome of the disease | Blood | 2011 | 268 |
| 35 | Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia | Blood | 2012 | 263 |
| 36 | Trk Receptor Expression and Inhibition in Neuroblastomas | Clinical Cancer Research | 2009 | 258 |
| 37 | Chemoreduction and Local Ophthalmic Therapy for Intraocular Retinoblastoma | Journal of Clinical Oncology | 2000 | 255 |
| 38 | Visual outcomes in children with neurofibromatosis type 1-associated optic pathway glioma following chemotherapy: a multicenter retrospective analysis | Neuro-Oncology | 2012 | 248 |
| 39 | Treatment of Posttraumatic Stress Symptoms in Adolescent Survivors of Childhood Cancer and Their Families: A Randomized Clinical Trial. | Journal of Family Psychology | 2004 | 247 |
| 40 | Mortality in Overweight and Underweight Children With Acute Myeloid Leukemia | JAMA - Journal of the American Medical Association | 2005 | 246 |
| 41 | Patterns of second malignant neoplasms in children | Cancer | 1977 | 241 |
| 42 | Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 233 |
| 43 | Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma | Nature Genetics | 2012 | 231 |
| 44 | Psychological Outcomes and Health Beliefs in Adolescent and Young Adult Survivors of Childhood Cancer and Controls | Journal of Clinical Oncology | 2010 | 230 |
| 45 | High-level expression of angiogenic factors is associated with advanced tumor stage in human neuroblastomas | Clinical Cancer Research | 2000 | 230 |
| 46 | Allelic deletion at 11q23 is common in MYCN single copy neuroblastomas | Oncogene | 1999 | 228 |
| 47 | The Psychosocial Assessment Tool (PAT2.0): Psychometric Properties of a Screener for Psychosocial Distress in Families of Children Newly Diagnosed with Cancer | Journal of Pediatric Psychology | 2008 | 228 |
| 48 | Pediatric Low-Grade Gliomas | Journal of Child Neurology | 2009 | 228 |
| 49 | Mechanisms of neuroblastoma regression | Nature Reviews Clinical Oncology | 2014 | 228 |
| 50 | Duplication of 7q34 in Pediatric Low‐Grade Astrocytomas Detected by High‐Density Single‐Nucleotide Polymorphism‐Based Genotype Arrays Results in a Novel BRAF Fusion Gene | Brain Pathology | 2009 | 227 |
