886(top 1%)
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37.9K(top 0.1%)
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citing journals

Top Articles

#TitleJournalYearCitations
1Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in CancerJournal of Molecular Diagnostics20171,267
2The Genetic Landscape of the Childhood Cancer MedulloblastomaScience2011652
3A genome-wide association study identifies KIAA0350 as a type 1 diabetes geneNature2007497
4Mitochondrial DNA Genetics and the Heteroplasmy Conundrum in Evolution and DiseaseCold Spring Harbor Perspectives in Biology2013496
5Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent MetabolismCell2018445
6Performance of ACMG-AMP Variant-Interpretation Guidelines among Nine Laboratories in the Clinical Sequencing Exploratory Research ConsortiumAmerican Journal of Human Genetics2016432
7Effect of plasma exchange on plasma ADAMTS13 metalloprotease activity, inhibitor level, and clinical outcome in patients with idiopathic and nonidiopathic thrombotic thrombocytopenic purpuraBlood2004431
8Comparative metabolomics in vegans and omnivores reveal constraints on diet-dependent gut microbiota metabolite productionGut2016428
9Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppressionNature Immunology2016402
10Mechanisms of mosaicism, chimerism and uniparental disomy identified by single nucleotide polymorphism array analysisHuman Molecular Genetics2010373
11The Hedgehog's tale: developing strategies for targeting cancerNature Reviews Cancer2011364
12HLA-DRB1*1101: A Significant Risk Factor for Sarcoidosis in Blacks and WhitesAmerican Journal of Human Genetics2003342
13Heteroplasmy of Mouse mtDNA Is Genetically Unstable and Results in Altered Behavior and CognitionCell2012333
14Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancerScience Translational Medicine2018326
15Spectrum of SMARCB1/INI1 mutations in familial and sporadic rhabdoid tumorsPediatric Blood and Cancer2011318
16Actionable exomic incidental findings in 6503 participants: challenges of variant classificationGenome Research2015313
17Helios Expression Is a Marker of T Cell Activation and ProliferationPLoS ONE2011312
18Recent advances in mRNA vaccine technologyCurrent Opinion in Immunology2020295
19Notch signaling in human development and diseaseSeminars in Cell and Developmental Biology2012286
20Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestrationNature Medicine2012285
21SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody GenerationImmunity2020285
22Three Linked Vasculopathic Processes Characterize Kawasaki Disease: A Light and Transmission Electron Microscopic StudyPLoS ONE2012284
23Next-generation sequencing technologies: An overviewHuman Immunology2021274
24A mitochondrial bioenergetic etiology of diseaseJournal of Clinical Investigation2013261
25H2AX Prevents DNA Breaks from Progressing to Chromosome Breaks and TranslocationsMolecular Cell2006258
26Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogrammingProceedings of the National Academy of Sciences of the United States of America2014251
27Endothelial TLR4 and the microbiome drive cerebral cavernous malformationsNature2017247
28Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade GliomasCancer Cell2020244
29Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineagesNature Cell Biology2015243
30Adult Autoimmune Enteropathy: Mayo Clinic Rochester ExperienceClinical Gastroenterology and Hepatology2007220
31Differential L1 regulation in pluripotent stem cells of humans and apesNature2013220
32Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liverBlood2007218
33SAP Regulates TH2 Differentiation and PKC-θ-Mediated Activation of NF-κB1Immunity2004215
34MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanismNature Genetics2016214
35Nkx6.1 Controls a Gene Regulatory Network Required for Establishing and Maintaining Pancreatic Beta Cell IdentityPLoS Genetics2013212
36Succinate Dehydrogenase Kidney Cancer: An Aggressive Example of the Warburg Effect in CancerJournal of Urology2012211
37TrkC Expression Predicts Good Clinical Outcome in Primitive Neuroectodermal Brain TumorsJournal of Clinical Oncology2000209
38Transient Inhibition of the Hedgehog Pathway in Young Mice Causes Permanent Defects in Bone StructureCancer Cell2008204
39F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activationJournal of Cell Biology2012203
40Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathwayELife2015200
41Mitochondrial DNA Variation in Human Radiation and DiseaseCell2015197
42Hepatic Fibrosis Is Universal Following Fontan Operation, and Severity is Associated With Time From Surgery: A Liver Biopsy and Hemodynamic StudyJournal of the American Heart Association2017195
43The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAsScience Translational Medicine2019192
44Self-Renewing Endodermal Progenitor Lines Generated from Human Pluripotent Stem CellsCell Stem Cell2012190
45Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapyBlood2016190
46From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 DiabetesPLoS Genetics2009186
47Protein Disulfide Isomerase A6 Controls the Decay of IRE1α Signaling via Disulfide-Dependent AssociationMolecular Cell2014186
48Sirtuin-1 Targeting Promotes Foxp3+ T-Regulatory Cell Function and Prolongs Allograft SurvivalMolecular and Cellular Biology2011184
49H+ transport is an integral function of the mitochondrial ADP/ATP carrierNature2019183
50Dosage Thresholds for AAV2 and AAV8 Photoreceptor Gene Therapy in MonkeyScience Translational Medicine2011179