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Top Articles

#TitleJournalYearCitations
1Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung CancerScience Translational Medicine2010761
2Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biologyCarcinogenesis2010422
3Staining of constitutive heterochromatin in mammalian chromosomes with a new fluorochromeExperimental Cell Research1972333
4MYCN regulates oncogenic MicroRNAs in neuroblastomaInternational Journal of Cancer2008251
5Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort studyLancet Oncology, The2011232
6Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumorsNature Genetics2014211
7Clinical trials on CIK cells: first report of the international registry on CIK cells (IRCC)Journal of Cancer Research and Clinical Oncology2011208
8A Sertoli Cell-Specific Knockout of Connexin43 Prevents Initiation of SpermatogenesisAmerican Journal of Pathology2007205
9Concurrent AURKA and MYCN Gene Amplifications Are Harbingers of Lethal TreatmentRelated Neuroendocrine Prostate CancerNeoplasia2013205
10Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous PolyposisAmerican Journal of Human Genetics2016198
11Mutations in a Gene Encoding a Novel SH3/TPR Domain Protein Cause Autosomal Recessive Charcot-Marie-Tooth Type 4C NeuropathyAmerican Journal of Human Genetics2003185
12Critical Function of AP-2gamma/TCFAP2C in Mouse Embryonic Germ Cell Maintenance1Biology of Reproduction2010172
13Loss of DNA Mismatch Repair Proteins in Skin Tumors From Patients With Muir–Torre Syndrome and MSH2 or MLH1 Germline MutationsAmerican Journal of Surgical Pathology2002169
14The multiple roles of tumour stromaVirchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin1997164
15Efficacy of Annual Colonoscopic Surveillance in Individuals With Hereditary Nonpolyposis Colorectal CancerClinical Gastroenterology and Hepatology2010160
16Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancerGut2012159
17Keratins: a structural scaffold with emerging functionsCellular and Molecular Life Sciences2003155
18Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association ConsortiumHuman Molecular Genetics2011152
19Breakthrough invasive fungal infections in neutropenic patients after prophylaxis with itraconazoleMycoses1999138
20Recurrence and variability of germline EPCAM deletions in Lynch syndromeHuman Mutation2011137
21Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosisScientific Reports2015127
22The Ets-1 transcription factor is up-regulated together with MMP 1 and MMP 9 in the stroma of pre-invasive breast cancerJournal of Pathology2001125
23Chromocolonoscopy detects more adenomas than white light colonoscopy or narrow band imaging colonoscopy in hereditary nonpolyposis colorectal cancer screeningEndoscopy2009120
24The Ets-1 transcription factor is involved in the development and invasion of malignant melanomaCellular and Molecular Life Sciences2004118
25Novel somatic mutations in primary hyperaldosteronism are related to the clinical, radiological and pathological phenotypeClinical Endocrinology2015115
26Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumoursOncogene2003109
27Expression of BLIMP1/PRMT5and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumorsBMC Developmental Biology2008107
28Beta2-microglobulin mutations in microsatellite unstable colorectal tumorsInternational Journal of Cancer2007100
29Novel insights into the function of CD24: A driving force in cancerInternational Journal of Cancer2021100
30CSE1L/CAS: its role in proliferation and apoptosisApoptosis: an International Journal on Programmed Cell Death200399
31Novel strategy for optimal sequential application of clinical criteria, immunohistochemistry and microsatellite analysis in the diagnosis of hereditary nonpolyposis colorectal cancerInternational Journal of Cancer200698
32Cold preservation of fatty liver grafts: prevention of functional and ultrastructural impairments by venous oxygen persufflationJournal of Hepatology200096
33Direct Induction of Trophoblast Stem Cells from Murine FibroblastsCell Stem Cell201593
34c-KIT is frequently mutated in bilateral germ cell tumours and down-regulated during progression from intratubular germ cell neoplasia to seminomaJournal of Pathology200792
35Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cellsNature Communications201692
36Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axisCell Stem Cell202192
37Prognostic significance of tumor-associated macrophages in endometrial adenocarcinomaGynecologic Oncology201491
38Tumours fromMSH2 mutation carriers show loss of MSH2 expression but many tumours fromMLH1 mutation carriers exhibit weak positive MLH1 stainingJournal of Pathology200590
39Novel tempeh (fermented soyabean) isoflavones inhibit in vivo angiogenesis in the chicken chorioallantoic membrane assayBritish Journal of Nutrition200587
40Transcription factor AP-2γ, a novel marker of gonocytes and seminomatous germ cell tumorsInternational Journal of Cancer200586
41HSC-specific inhibition of Rho-kinase reduces portal pressure in cirrhotic rats without major systemic effectsJournal of Hepatology201286
42A mouse model for cystic biliary dysgenesis in autosomal recessive polycystic kidney disease (ARPKD)Hepatology200584
43MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cellsOncogene201384
44Lysine-specific demethylase 1 (LSD1) in hematopoietic and lymphoid neoplasmsBlood201484
45Frequency of Microsatellite Instability in Unselected Sebaceous Gland Neoplasias and HyperplasiasJournal of Investigative Dermatology200382
46Senescent Fibroblasts Enhance Early Skin Carcinogenic Events via a Paracrine MMP-PAR-1 AxisPLoS ONE201382
47Derivation and Maintenance of Murine Trophoblast Stem Cells under Defined ConditionsStem Cell Reports201482
48Gleason grade 4 prostate adenocarcinoma patterns: an interobserver agreement study among genitourinary pathologistsHistopathology201682
49Epigenetics in Male Germ CellsJournal of Andrology200780
50Epigenetic regulation of cancer growth by histone demethylasesInternational Journal of Cancer201080