| # | Title | Journal | Year | Citations |
|---|
| 1 | Expression and Characterization of Hypoxia-Inducible Factor (HIF)-3α in Human Kidney: Suppression of HIF-Mediated Gene Expression by HIF-3α | Biochemical and Biophysical Research Communications | 2001 | 245 |
| 2 | Transcriptional regulation of thioredoxin reductase 1 expression by cadmium in vascular endothelial cells: Role of NF-E2-related factor-2 | Journal of Cellular Physiology | 2005 | 163 |
| 3 | Human HIF‐3α4 is a dominant‐negative regulator of HIF‐1 and is down‐regulated in renal cell carcinoma | FASEB Journal | 2005 | 161 |
| 4 | Enhancement of Androgen-Dependent Transcription and Cell Proliferation by Tributyltin and Triphenyltin in Human Prostate Cancer Cells | Toxicology and Applied Pharmacology | 2000 | 78 |
| 5 | The Involvement of Microtubular Disruption in Methylmercury-Induced Apoptosis in Neuronal and Nonneuronal Cell Lines | Toxicology and Applied Pharmacology | 1999 | 72 |
| 6 | cAMP-induced Astrocytic Differentiation of C6 Glioma Cells Is Mediated by Autocrine Interleukin-6 | Journal of Biological Chemistry | 2004 | 72 |
| 7 | Modulation of telomerase activity by zinc in human prostatic and renal cancer cells | Biochemical Pharmacology | 2000 | 69 |
| 8 | The MerE protein encoded by transposon Tn21 is a broad mercury transporter in Escherichia coli | FEBS Letters | 2009 | 67 |
| 9 | EPAS1 Promotes Adipose Differentiation in 3T3-L1 Cells | Journal of Biological Chemistry | 2004 | 66 |
| 10 | Overexpression of thioredoxin reductase 1 regulates NF-?B activation | Journal of Cellular Physiology | 2004 | 64 |
| 11 | Effects of Selenium Deficiency on Expression of Selenoproteins in Bovine Arterial Endothelial Cells. | Biological and Pharmaceutical Bulletin | 2001 | 52 |
| 12 | Aggravating Impact of Nanoparticles on Immune-Mediated Pulmonary Inflammation | Scientific World Journal, The | 2011 | 50 |
| 13 | Role of MerC, MerE, MerF, MerT, and/or MerP in Resistance to Mercurials and the Transport of Mercurials in <i>Escherichia coli</i> | Biological and Pharmaceutical Bulletin | 2013 | 50 |
| 14 | Mercurial-resistance determinants in Pseudomonas strain K-62 plasmid pMR68 | AMB Express | 2013 | 47 |
| 15 | Hypoxia-Inducible Factor-3.ALPHA. Functions as an Accelerator of 3T3-L1 Adipose Differentiation | Biological and Pharmaceutical Bulletin | 2009 | 43 |
| 16 | Cellular Cadmium Uptake Mediated by the Transport System for Manganese. | Tohoku Journal of Experimental Medicine | 2002 | 42 |
| 17 | Suppression of a high-affinity transport system for manganese in cadmium-resistant metallothionein-null cells | Journal of Pharmacology and Experimental Therapeutics | 2000 | 39 |
| 18 | Bacterial heavy metal transporter MerC increases mercury accumulation in Arabidopsis thaliana | Biochemical Engineering Journal | 2013 | 38 |
| 19 | Vitamin K has the potential to protect neurons from methylmercury‐induced cell death In Vitro | Journal of Neuroscience Research | 2011 | 35 |
| 20 | Expression of the bacterial heavy metal transporter MerC fused with a plant SNARE, SYP121, in Arabidopsis thaliana increases cadmium accumulation and tolerance | Planta | 2012 | 35 |
| 21 | Involvement of Oxidative Stress in Paraquat-Induced Metallothionein Synthesis Under Glutathione Depletion | Free Radical Biology and Medicine | 1998 | 34 |
| 22 | Atg5-dependent autophagy plays a protective role against methylmercury-induced cytotoxicity | Toxicology Letters | 2016 | 34 |
| 23 | Role of antioxidant systems in human androgen-independent prostate cancer cells | Prostate | 2000 | 33 |
| 24 | Promoting effects of nanoparticles/materials on sensitive lung inflammatory diseases | Environmental Health and Preventive Medicine | 2011 | 33 |
| 25 | Effects of Methylmercury and Inorganic Mercury on the Growth of Nerve Fibers in Cultured Chick Dorsal Root Ganglia | Tohoku Journal of Experimental Medicine | 2000 | 31 |
| 26 | Overexpression of manganese-superoxide dismutase prevents methylmercury tox1city in hela cells | Life Sciences | 1998 | 30 |
| 27 | Neuronal nitric oxide synthase (NNOS) catalyzes one-electron reduction of 2,4,6-trinitrotoluene, resulting in decreased nitric oxide production and increased nNOS gene expression: implication for oxidative stress | Free Radical Biology and Medicine | 2004 | 30 |
| 28 | Reduced uptake and enhanced release of cadmium in cadmium-resistant metallothionein null fibroblasts | Life Sciences | 1999 | 29 |
| 29 | Metallothionein-Mediated Resistance to Multiple Drugs Can Be Induced by Several Anticancer Drugs in Mice | Biochemical and Biophysical Research Communications | 1998 | 28 |
| 30 | Modulation of adriamycin toxicity by tissue-specific induction of metallothionein synthesis in mice | Life Sciences | 2000 | 27 |
| 31 | Effect of preinductin of metallothionein synthesis on clastogenicity of anticancer drugs in mice | Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis | 1995 | 25 |
| 32 | Host factors required for internal initiation of translation on poliovirus RNA | Archives of Virology | 1994 | 24 |
| 33 | Induction of Hepatic Metallothionein by Trivalent Cerium: Role of Interleukin 6 | Biological and Pharmaceutical Bulletin | 2005 | 24 |
| 34 | Enhancement of paraquat toxicity by glutathione depletion in mice in vivo and in vitro. | Journal of Toxicological Sciences | 1995 | 23 |
| 35 | Increase methylmercury accumulation in Arabidopsis thaliana expressing bacterial broad-spectrum mercury transporter MerE | AMB Express | 2013 | 23 |
| 36 | Roles Played by MerE and MerT in the Transport of Inorganic and Organic Mercury Compounds in Gram-negative Bacteria | Journal of Health Science | 2010 | 22 |
| 37 | Glutathione content is correlated with the sensitivity of lines of PC12 cells to cisplatin without a corresponding change in the accumulation of platinum | Molecular and Cellular Biochemistry | 2001 | 21 |
| 38 | Inhibitory Effect of Selenium on Biliary Secretion of Methyl Mercury in Rats | Biochemical and Biophysical Research Communications | 1997 | 20 |
| 39 | Metallothionein modulates the carcinogenicity of N-butyl-N-(4-hydroxybutyl)nitrosamine in mice | Carcinogenesis | 1999 | 19 |
| 40 | Engineering expression of the heavy metal transporter MerC in Saccharomyces cerevisiae for increased cadmium accumulation | Applied Microbiology and Biotechnology | 2010 | 19 |
| 41 | Subcellular localization and regulation of hypoxia-inducible factor-2α in vascular endothelial cells | Biochemical and Biophysical Research Communications | 2004 | 17 |
| 42 | Acceleration of methylmercury-induced cell death of rat cerebellar neurons by brain-derived neurotrophic factor in vitro | Brain Research | 2009 | 17 |
| 43 | Classification of Patients Complaining of Sick House Syndrome and/or Multiple Chemical Sensitivity | Tohoku Journal of Experimental Medicine | 2007 | 16 |
| 44 | Effects of nanoparticle-rich diesel exhaust particles on IL-17 productionin vitro | Journal of Immunotoxicology | 2012 | 16 |
| 45 | Suppressed Proliferative Response of Spleen T Cells from Metallothionein Null Mice | Microbiology and Immunology | 2002 | 15 |
| 46 | Particulate Matter–Induced Health Effects: Who Is Susceptible? | Environmental Health Perspectives | 2011 | 15 |
| 47 | Effects of exposure to nanoparticle-rich or -depleted diesel exhaust on allergic pathophysiology in the murine lung | Journal of Toxicological Sciences | 2013 | 15 |
| 48 | Effect of Glutathione Depletion on Metallothionein Synthesis Induced by Paraquat in Mice. | Tohoku Journal of Experimental Medicine | 1995 | 14 |
| 49 | Application of metallothionein null cells to investigation of cadmium transport | Journal of Inorganic Biochemistry | 2002 | 13 |
| 50 | Caveolae-mediated Endocytosis of Intratracheally Instilled Gold Colloid Nanoparticles at the Air–Blood Barrier in Mice | Toxicologic Pathology | 2013 | 13 |
