| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 2 | A Comparison of Symptom Prevalence in Far Advanced Cancer, AIDS, Heart Disease, Chronic Obstructive Pulmonary Disease and Renal Disease | Journal of Pain and Symptom Management | 2006 | 966 |
| 3 | Etiology of the Protein-Energy Wasting Syndrome in Chronic Kidney Disease: A Consensus Statement From the International Society of Renal Nutrition and Metabolism (ISRNM) | | 2013 | 606 |
| 4 | Epidemiology of endemic systemic fungal infections in Latin America | Medical Mycology | 2011 | 269 |
| 5 | Hypothalamus‐Pituitary‐Thyroid Axis | | 2016 | 263 |
| 6 | Mutations in Potassium Channel Kir2.6 Cause Susceptibility to Thyrotoxic Hypokalemic Periodic Paralysis | Cell | 2010 | 245 |
| 7 | Chromoblastomycosis | Clinical Microbiology Reviews | 2017 | 234 |
| 8 | Cognitive–behavioral group therapy is an effective treatment for major depression in hemodialysis patients | Kidney International | 2009 | 201 |
| 9 | Two PrevalentCYP17Mutations and Genotype-Phenotype Correlations in 24 Brazilian Patients with 17-Hydroxylase Deficiency | Journal of Clinical Endocrinology and Metabolism | 2004 | 194 |
| 10 | Bacterial Sensing, Cell Signaling, and Modulation of the Immune Response During Sepsis | Shock | 2012 | 180 |
| 11 | Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia | Nature Communications | 2018 | 175 |
| 12 | Remodeling of the Immune Response With Aging: Immunosenescence and Its Potential Impact on COVID-19 Immune Response | Frontiers in Immunology | 2020 | 169 |
| 13 | Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis | Journal of Clinical Endocrinology and Metabolism | 2015 | 164 |
| 14 | Inhibition of Stat3 Activation Suppresses Caspase-3 and the Ubiquitin-Proteasome System, Leading to Preservation of Muscle Mass in Cancer Cachexia | Journal of Biological Chemistry | 2015 | 164 |
| 15 | A preoperative diagnostic test that distinguishes benign from malignant thyroid carcinoma based on gene expression | Journal of Clinical Investigation | 2004 | 162 |
| 16 | Late diagnosis of chronic renal failure and mortality on maintenance dialysis | Nephrology Dialysis Transplantation | 1996 | 159 |
| 17 | Epidemiology and Microbiologic Characterization of Nosocomial Candidemia from a Brazilian National Surveillance Program | PLoS ONE | 2016 | 146 |
| 18 | Aberrant overexpression and function of the miR-17-92 cluster in MLL -rearranged acute leukemia | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 141 |
| 19 | Oxidative Stress in the Sympathetic Premotor Neurons Contributes to Sympathetic Activation in Renovascular Hypertension | American Journal of Hypertension | 2009 | 134 |
| 20 | A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans | Human Molecular Genetics | 2010 | 133 |
| 21 | Paracrine signaling by glial cell–derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells | Journal of Clinical Investigation | 2010 | 133 |
| 22 | Immune Regulatory Properties of Allogeneic Adipose-Derived Mesenchymal Stem Cells in the Treatment of Experimental Autoimmune Diabetes | Diabetes | 2012 | 131 |
| 23 | Abandon the Mouse Research Ship? Not Just Yet! | Shock | 2014 | 126 |
| 24 | Candida and invasive mould diseases in non-neutropenic critically ill patients and patients with haematological cancer | Lancet Infectious Diseases, The | 2017 | 124 |
| 25 | Sleep Disturbance Scale for Children: Translation, cultural adaptation, and validation | Sleep Medicine | 2009 | 123 |
| 26 | Sodium nitrite downregulates vascular NADPH oxidase and exerts antihypertensive effects in hypertension | Free Radical Biology and Medicine | 2011 | 123 |
| 27 | Monocyte subtypes and the CCR2 chemokine receptor in cardiovascular disease | Clinical Science | 2017 | 123 |
| 28 | miR-27a Regulates Inflammatory Response of Macrophages by Targeting IL-10 | Journal of Immunology | 2014 | 121 |
| 29 | One Month Is Sufficient for Urinary Iodine to Return to Its Baseline Value After the Use of Water-Soluble Iodinated Contrast Agents in Post-Thyroidectomy Patients Requiring Radioiodine Therapy | Thyroid | 2012 | 110 |
| 30 | Epidemiological and clinical features of human coronavirus infections among different subsets of patients | Influenza and Other Respiratory Viruses | 2013 | 109 |
| 31 | A Mutation in the KCNE3 Potassium Channel Gene Is Associated with Susceptibility to Thyrotoxic Hypokalemic Periodic Paralysis | Journal of Clinical Endocrinology and Metabolism | 2002 | 106 |
| 32 | Early Improvement in Glycemic Control After Bariatric Surgery and Its Relationships with Insulin, GLP-1, and Glucagon Secretion in Type 2 Diabetic Patients | Obesity Surgery | 2011 | 106 |
| 33 | Subclinical thyroid dysfunctions are independent risk factors for mortality in a 7.5-year follow-up: the Japanese–Brazilian thyroid study | European Journal of Endocrinology | 2010 | 104 |
| 34 | Diagnosis and Evaluation of Hypersensitivity Pneumonitis | Chest | 2021 | 104 |
| 35 | A Novel Germ-Line Point Mutation in RET Exon 8 (Gly533Cys) in a Large Kindred with Familial Medullary Thyroid Carcinoma | Journal of Clinical Endocrinology and Metabolism | 2003 | 103 |
| 36 | Stunted children gain less lean body mass and more fat mass than their non-stunted counterparts: a prospective study | British Journal of Nutrition | 2004 | 101 |
| 37 | Cathepsin L in COVID-19: From Pharmacological Evidences to Genetics | Frontiers in Cellular and Infection Microbiology | 2020 | 101 |
| 38 | Isolation and biochemical characterization of a fibrinolytic proteinase from Bothrops leucurus (white-tailed jararaca) snake venom | Biochimie | 2006 | 93 |
| 39 | Outbreak of Candida rugosa candidemia: an emerging pathogen that may be refractory to amphotericin B therapy | Diagnostic Microbiology and Infectious Disease | 2003 | 90 |
| 40 | Visual Scapular Dyskinesis: Kinematics and Muscle Activity Alterations in Patients With Subacromial Impingement Syndrome | Archives of Physical Medicine and Rehabilitation | 2015 | 89 |
| 41 | Skeletal muscle structure and function in response to electrical stimulation in moderately impaired COPD patients | Respiratory Medicine | 2007 | 87 |
| 42 | Oxidative Stress Contributes to Renovascular Hypertension | American Journal of Hypertension | 2008 | 87 |
| 43 | Inspiratory fraction and exercise impairment in COPD patients GOLD stages II-III | European Respiratory Journal | 2006 | 85 |
| 44 | Angiotensin II Facilitates Breast Cancer Cell Migration and Metastasis | PLoS ONE | 2012 | 84 |
| 45 | Serum albumin and clinical outcome in pediatric cardiac surgery | Nutrition | 2005 | 83 |
| 46 | Practical determination of hyaluronan by a new noncompetitive fluorescence-based assay on serum of normal and cirrhotic patients | Analytical Biochemistry | 2003 | 81 |
| 47 | Effect of 6-month nutritional intervention on non-alcoholic fatty liver disease | Nutrition | 2010 | 81 |
| 48 | Investigation of BRAF mutation in a series of papillary thyroid carcinoma and matched-lymph node metastasis reveals a new mutation in metastasis | Clinical Endocrinology | 2005 | 80 |
| 49 | Treatment options for paracoccidioidomycosis and new strategies investigated | Expert Review of Anti-Infective Therapy | 2008 | 80 |
| 50 | Fine Needle Aspiration and Medullary Thyroid Carcinoma: The Risk of Inadequate Preoperative Evaluation and Initial Surgery when Relying upon Fnab Cytology Alone | Endocrine Practice | 2013 | 80 |
