| # | Title | Journal | Year | Citations |
|---|
| 1 | A novel influenza A virus mitochondrial protein that induces cell death | Nature Medicine | 2001 | 901 |
| 2 | Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells | Journal of Experimental Medicine | 2010 | 689 |
| 3 | Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification | Nature Genetics | 2003 | 539 |
| 4 | mRNA Silencing in Erythroid Differentiation: hnRNP K and hnRNP E1 Regulate 15-Lipoxygenase Translation from the 3′ End | Cell | 1997 | 467 |
| 5 | Comparative resistance of the 20S and 26S proteasome to oxidative stress | Biochemical Journal | 1998 | 410 |
| 6 | Molecular actions of Ebselen—an antiinflammatory antioxidant | General Pharmacology | 1995 | 386 |
| 7 | Structure of the signal recognition particle interacting with the elongation-arrested ribosome | Nature | 2004 | 382 |
| 8 | COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system | EMBO Journal | 2001 | 349 |
| 9 | A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits | FASEB Journal | 1998 | 346 |
| 10 | A protein of the endoplasmic reticulum involved early in polypeptide translocation | Nature | 1992 | 310 |
| 11 | SIRT1 Regulates HIV Transcription via Tat Deacetylation | PLoS Biology | 2005 | 292 |
| 12 | The diversity of the lipoxygenase family | FEBS Letters | 1999 | 282 |
| 13 | Coordinated Dual Cleavages Induced by the Proteasome Regulator PA28 Lead to Dominant MHC Ligands | Cell | 1996 | 280 |
| 14 | Translation of 15-lipoxygenase mRNA is inhibited by a protein that binds to a repeated sequence in the 3′ untranslated region. | EMBO Journal | 1994 | 244 |
| 15 | Efficient Identification of Novel Hla-A*0201–Presented Cytotoxic T Lymphocyte Epitopes in the Widely Expressed Tumor Antigen Prame by Proteasome-Mediated Digestion Analysis | Journal of Experimental Medicine | 2001 | 236 |
| 16 | The Automatic Search for Ligand Binding Sites in Proteins of Known Three-dimensional Structure Using only Geometric Criteria | Journal of Molecular Biology | 1996 | 234 |
| 17 | Oxygenation of biological membranes by the pure reticulocyte lipoxygenase. | Journal of Biological Chemistry | 1990 | 227 |
| 18 | Regulatory subunit interactions of the 26S proteasome, a complex problem | Trends in Biochemical Sciences | 2000 | 219 |
| 19 | Regulation of enzymatic lipid peroxidation: the interplay of peroxidizing and peroxide reducing enzymes1 1This article is part of a series of reviews on “Regulatory and Cytoprotective Aspects of Lipid Hydroperoxide Metabolism.” The full list of papers may be found on the homepage of the journal. | Free Radical Biology and Medicine | 2002 | 209 |
| 20 | STRAP: editor for STRuctural Alignments of Proteins | Bioinformatics | 2001 | 208 |
| 21 | Involvement of 15-lipoxygenase in early stages of atherogenesis. | Journal of Experimental Medicine | 1994 | 190 |
| 22 | Oxygenation of biological membranes by the pure reticulocyte lipoxygenase | Journal of Biological Chemistry | 1990 | 184 |
| 23 | Mammalian arachidonate 15-lipoxygenases | Prostaglandins and Other Lipid Mediators | 2002 | 176 |
| 24 | Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome | EMBO Journal | 2003 | 176 |
| 25 | The Selenoenzyme Phospholipid Hydroperoxide Glutathione Peroxidase Controls the Activity of the 15-Lipoxygenase with Complex Substrates and Preserves the Specificity of the Oxygenation Products | Journal of Biological Chemistry | 1996 | 171 |
| 26 | Prostaglandin F2-Like Compounds, F2-Isoprostanes, Are Present in Increased Amounts in Human Atherosclerotic Lesions | Arteriosclerosis, Thrombosis, and Vascular Biology | 1997 | 168 |
| 27 | Defined Flanking Spacers and Enhanced Proteolysis Is Essential for Eradication of Established Tumors by an Epitope String DNA Vaccine | Journal of Immunology | 2001 | 162 |
| 28 | In vivo action of 15-lipoxygenase in early stages of human atherogenesis. | Journal of Clinical Investigation | 1997 | 154 |
| 29 | A tetrameric complex of membrane proteins in the endoplasmic reticulum | FEBS Journal | 1993 | 149 |
| 30 | Structure of eEF3 and the mechanism of transfer RNA release from the E-site | Nature | 2006 | 147 |
| 31 | Oxygenation of lipoproteins by mammalian lipoxygenases | FEBS Journal | 1993 | 145 |
| 32 | Efficient Generation of a Hepatitis B Virus Cytotoxic T Lymphocyte Epitope Requires the Structural Features of Immunoproteasomes | Journal of Experimental Medicine | 2000 | 140 |
| 33 | Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain | EMBO Journal | 2002 | 126 |
| 34 | Activated Platelets and Monocytes Generate Four Hydroxyphosphatidylethanolamines via Lipoxygenase | Journal of Biological Chemistry | 2007 | 125 |
| 35 | Shape and Specificity in Mammalian 15-Lipoxygenase Active Site | Journal of Biological Chemistry | 1999 | 123 |
| 36 | PB1-F2, an Influenza A Virus-Encoded Proapoptotic Mitochondrial Protein, Creates Variably Sized Pores in Planar Lipid Membranes | Journal of Virology | 2004 | 121 |
| 37 | A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits | FASEB Journal | 1998 | 120 |
| 38 | Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities | Journal of Lipid Research | 1994 | 119 |
| 39 | Phospholipid-esterified Eicosanoids Are Generated in Agonist-activated Human Platelets and Enhance Tissue Factor-dependent Thrombin Generation | Journal of Biological Chemistry | 2010 | 115 |
| 40 | Acetylation of Tat Defines a CyclinT1-Independent Step in HIV Transactivation | Molecular Cell | 2003 | 113 |
| 41 | Interleukin-4 and -13 Induce Upregulation of the Murine Macrophage 12/15-Lipoxygenase Activity: Evidence for the Involvement of Transcription Factor STAT6 | Blood | 1998 | 108 |
| 42 | MHC Class I Antigen Processing of an Adenovirus CTL Epitope Is Linked to the Levels of Immunoproteasomes in Infected Cells | Journal of Immunology | 2000 | 105 |
| 43 | PI31 is a modulator of proteasome formation and antigen processing | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 104 |
| 44 | A kinetic model for lipoxygenases based on experimental data with the lipoxygenase of reticulocytes | FEBS Journal | 1987 | 103 |
| 45 | HIV-1 Tat Inhibits the 20 S Proteasome and Its 11 S Regulator-mediated Activation | Journal of Biological Chemistry | 1997 | 103 |
| 46 | The Rabbit 15-Lipoxygenase Preferentially Oxygenates LDL Cholesterol Esters, and This Reaction Does Not Require Vitamin E | Journal of Biological Chemistry | 1998 | 102 |
| 47 | Functional and Structural Characterization of Synthetic HIV-1 Vpr That Transduces Cells, Localizes to the Nucleus, and Induces G2 Cell Cycle Arrest | Journal of Biological Chemistry | 2000 | 102 |
| 48 | Differential Influence on Cytotoxic T Lymphocyte Epitope Presentation by Controlled Expression of Either Proteasome Immunosubunits or Pa28 | Journal of Experimental Medicine | 2000 | 100 |
| 49 | Prediction of temporal gene expression | FEBS Journal | 2002 | 98 |
| 50 | Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities | Journal of Lipid Research | 1994 | 98 |
