| # | Title | Journal | Year | Citations |
|---|
| 1 | The genetic determinants of the CYP3A5 polymorphism | Pharmacogenetics and Genomics | 2001 | 608 |
| 2 | The European Association for Endoscopic Surgery clinical practice guideline on the pneumoperitoneum for laparoscopic surgery | Surgical Endoscopy and Other Interventional Techniques | 2002 | 533 |
| 3 | Diagnosis and treatment of diverticular disease | Surgical Endoscopy and Other Interventional Techniques | 1999 | 463 |
| 4 | Sex is a major determinant of CYP3A4 expression in human liver | Hepatology | 2003 | 426 |
| 5 | COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system | EMBO Journal | 2001 | 349 |
| 6 | Cytomegalovirus reactivation and tumour necrosis factor | Lancet, The | 1994 | 281 |
| 7 | Sex is a major determinant of CYP3A4 expression in human liver | Hepatology | 2003 | 244 |
| 8 | Laparoscopic resection of colon Cancer: Consensus of the European Association of Endoscopic Surgery (EAES) | Surgical Endoscopy and Other Interventional Techniques | 2004 | 231 |
| 9 | Pneumoperitoneum with carbon dioxide stimulates growth of malignant colonic cells | Surgery | 1997 | 213 |
| 10 | Local recurrence rates after radiofrequency ablation or resection of colorectal liver metastases. Analysis of the European Organisation for Research and Treatment of Cancer #40004 and #40983 | European Journal of Cancer | 2014 | 190 |
| 11 | Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome | EMBO Journal | 2003 | 176 |
| 12 | Venous complications after orthotopic liver transplantation | Clinical Transplantation | 2000 | 173 |
| 13 | Caspase Activation Inhibits Proteasome Function during Apoptosis | Molecular Cell | 2004 | 167 |
| 14 | Molecular Mechanisms of Polymorphic CYP3A7 Expression in Adult Human Liver and Intestine | Journal of Biological Chemistry | 2002 | 164 |
| 15 | Renal replacement therapy with high-cutoff hemofilters: impact of convection and diffusion on cytokine clearances and protein status | American Journal of Kidney Diseases | 2004 | 163 |
| 16 | Viral dynamics of hepatitis C early after orthotopic liver transplantation: Evidence for rapid turnover of serum virions | Hepatology | 1996 | 159 |
| 17 | Liver metastases: interventional therapeutic techniques and results, state of the art | European Radiology | 1999 | 142 |
| 18 | Does pneumoperitoneum with different gases, body positions, and intraperitoneal pressures influence renal and hepatic blood flow? | Surgery | 1997 | 141 |
| 19 | The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis | Journal of Cell Science | 2002 | 137 |
| 20 | Preoperative evaluation of malignant liver tumors: comparison of unenhanced and SPIO (Resovist)-enhanced MR imaging with biphasic CTAP and intraoperative US | European Radiology | 2003 | 135 |
| 21 | A Naturally Occurring Mutation in the SLC21A6Gene Causing Impaired Membrane Localization of the Hepatocyte Uptake Transporter | Journal of Biological Chemistry | 2002 | 127 |
| 22 | Trends and experiences in liver retransplantation over 15 years | Liver Transplantation | 2007 | 123 |
| 23 | Prospective Randomized Study Comparing Laparoscopic and Open Tension-free Inguinal Hernia Repair with Shouldice’s Operation | American Journal of Surgery | 1998 | 122 |
| 24 | Influence of Donor Brain Death on Chronic Rejection of Renal Transplants in Rats | Journal of the American Society of Nephrology: JASN | 2001 | 119 |
| 25 | The influence ofCYP2B6,CYP2C9andCYP2D6genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver | British Journal of Clinical Pharmacology | 2002 | 118 |
| 26 | The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis | Journal of Cell Science | 2002 | 117 |
| 27 | Primary Human Liver Cells as Source for Modular Extracorporeal Liver Support - a Preliminary Report | International Journal of Artificial Organs | 2002 | 109 |
| 28 | Diagnosis and treatment of arterial steal syndromes in liver transplant recipients | Liver Transplantation | 2003 | 108 |
| 29 | Effects of Pneumoperitoneum With Carbon Dioxide, Argon, or Helium on Hemodynamic and Respiratory Function | Archives of Surgery | 1997 | 99 |
| 30 | Use of primary human liver cells originating from discarded grafts in a bioreactor for liver support therapy and the prospects of culturing adult liver stem cells in bioreactors: a morphologic study | Transplantation | 2003 | 94 |
| 31 | THE RELEASE OF CYTOKINES, ADHESION MOLECULES, AND EXTRACELLULAR MATRIX PARAMETERS DURING AND AFTER REPERFUSION IN HUMAN LIVER TRANSPLANTATION | Transplantation | 1996 | 92 |
| 32 | Nab-paclitaxel plus gemcitabine versus nab-paclitaxel plus gemcitabine followed by FOLFIRINOX induction chemotherapy in locally advanced pancreatic cancer (NEOLAP-AIO-PAK-0113): a multicentre, randomised, phase 2 trial | The Lancet Gastroenterology and Hepatology | 2021 | 89 |
| 33 | Surgical therapy of esophageal carcinoma: the influence of surgical approach and esophageal resection on cardiopulmonary function | European Journal of Cardio-thoracic Surgery | 1997 | 85 |
| 34 | MYCOPHENOLATEMOFETIL FOR IMMUNOSUPPRESSION AFTER LIVER TRANSPLANTATION | Transplantation | 2003 | 82 |
| 35 | Impact of laparoscopic colonic resection on tumour growth and spread in an experimental model | British Journal of Surgery | 2002 | 81 |
| 36 | Quality of life after surgical therapy of bronchogenic carcinoma | European Journal of Cardio-thoracic Surgery | 1996 | 80 |
| 37 | Inhibition of peritoneal tumor cell growth and implantation in laparoscopic surgery in a rat model | American Journal of Surgery | 1997 | 78 |
| 38 | Staging of Klatskin tumours (hilar cholangiocarcinomas): comparison of MR cholangiography, MR imaging, and endoscopic retrograde cholangiography | European Radiology | 2006 | 77 |
| 39 | The Impact of Laparoscopy with Carbon Dioxide versus Helium on Immunologic Function and Tumor Growth in a Rat Model | Digestive Surgery | 1998 | 76 |
| 40 | Genetic polymorphisms of glutathione S-transferase A1, the major glutathione S-transferase in human liver: Consequences for enzyme expression and busulfan conjugation* | Clinical Pharmacology and Therapeutics | 2002 | 73 |
| 41 | Experimental study of the effect of intra-abdominal pressure during laparoscopy on tumour growth and port site metastasis | British Journal of Surgery | 2003 | 71 |
| 42 | The influence of laparotomy and laparoscopy on tumor growth in a rat model | Surgical Endoscopy and Other Interventional Techniques | 1997 | 70 |
| 43 | Prognostic Factors in Patients with Differentiated Thyroid Carcinoma | The European Journal of Surgery | 2000 | 69 |
| 44 | Cardiovascular risk factors in long-term follow-up after orthotopic liver transplantation | Clinical Transplantation | 1997 | 69 |
| 45 | Increased Systemic Inflammation After Laparotomy vs Laparoscopy in an Animal Model of Peritonitis | Archives of Surgery | 1998 | 68 |
| 46 | INFLUENZA VACCINATION IN LIVER TRANSPLANT RECIPIENTS | Transplantation | 1999 | 67 |
| 47 | TREATMENT OF CYCLOSPORINE-RELATED ADVERSE EFFECTS BY CONVERSION TO TACROLIMUS AFTER LIVER TRANSPLANTATION | Transplantation | 1997 | 65 |
| 48 | Liver graft-transmitted glioblastoma multiforme. A case report and experience with 13 multiorgan donors suffering from primary cerebral neoplasia | Transplant International | 1996 | 63 |
| 49 | TRANSPLANTATION OF ORGANS FROM MARGINAL DONORS1 | Transplantation | 2001 | 60 |
| 50 | Characterization of Lipid and Lipid Droplet Metabolism in Human HCC | Cells | 2019 | 60 |
