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Top Articles

#TitleJournalYearCitations
1Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19Nature Neuroscience2021991
2Vascular invasion and histopathologic grading determine outcome after liver transplantation for hepatocellular carcinoma in cirrhosisHepatology2001826
3Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?Experimental Cell Research1995781
4Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblastsFree Radical Biology and Medicine2000479
5Preferential Accumulation of Single-Stranded Regions in Telomeres of Human FibroblastsExperimental Cell Research1998380
6Fungi and inflammatory bowel diseases: Alterations of composition and diversityScandinavian Journal of Gastroenterology2008375
7Role of Oxidative Stress in Telomere Length Regulation and Replicative SenescenceAnnals of the New York Academy of Sciences2000369
8Short Telomeres in Patients with Vascular Dementia: An Indicator of Low Antioxidative Capacity and a Possible Risk Factor?Laboratory Investigation2000290
9Proteasome inhibition by lipofuscin/ceroid during postmitotic aging of fibroblastsFASEB Journal2000269
10A genome-wide survey of RAS transformation targetsNature Genetics2000265
11Caveolin-1 Is Down-Regulated in Human Ovarian Carcinoma and Acts as a Candidate Tumor Suppressor GeneAmerican Journal of Pathology2001260
12Grading of Chronic Synovitis — A Histopathological Grading System for Molecular and Diagnostic PathologyPathology Research and Practice2002257
13ABC-transporters: implications on drug resistance from microorganisms to human cancersInternational Journal of Antimicrobial Agents2003255
14Proteasome inhibition by lipofuscin/ceroid during postmitotic aging of fibroblastsFASEB Journal2000242
15Loss of PDCD4 expression in human lung cancer correlates with tumour progression and prognosisJournal of Pathology2003242
16Assessment of the PD-L1 status by immunohistochemistry: challenges and perspectives for therapeutic strategies in lung cancer patientsVirchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin2016212
17Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part I— effects of proliferative senescenceFASEB Journal2000202
18Immunoglobulin and T-cell receptor gene rearrangements in Hodgkin's disease and Ki-1-positive anaplastic large cell lymphoma: Dissociation between phenotype and genotypeLeukemia Research1989187
19High-accuracy determination of internal circadian time from a single blood sampleJournal of Clinical Investigation2018174
20Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi)FEBS Letters2003172
21Polo-like kinase isoform expression is a prognostic factor in ovarian carcinomaBritish Journal of Cancer2004157
22Bone marrow microvessel density is a prognostic factor for survival in patients with multiple myelomaAnnals of Hematology2000155
23Accelerated Telomere Shortening in Fibroblasts After Extended Periods of ConfluencyFree Radical Biology and Medicine1998150
24Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part II—aging of nondividing cellsFASEB Journal2000148
25SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itselfNature Communications2021145
26Immunohistochemical differentiation of metastatic breast carcinomas from metastatic adenocarcinomas of other common primary sitesHistopathology1996142
27Aberrant right subclavian artery as a new cardiac sign in second- and third-trimester fetuses with Down syndromeAmerican Journal of Obstetrics and Gynecology2005133
28Genetic Imbalances with Impact on Survival in Head and Neck Cancer PatientsAmerican Journal of Pathology2000117
29Targeting non-coding RNAs to overcome cancer therapy resistanceSignal Transduction and Targeted Therapy2022114
30Absent or hypoplastic thymus on ultrasound: a marker for deletion 22q11.2 in fetal cardiac defectsUltrasound in Obstetrics and Gynecology2002113
31US-based Real-time Elastography for the Detection of Fibrotic Gut Tissue in Patients with Stricturing Crohn DiseaseRadiology2015111
32Overexpression of cMOAT (MRP2/ABCC2) Is Associated with Decreased Formation of Platinum-DNA Adducts and Decreased G2-Arrest in Melanoma Cells Resistant to CisplatinJournal of Investigative Dermatology2003106
33Splicing Factor SRp30c Interaction with Y-box Protein-1 Confers Nuclear YB-1 Shuttling and Alternative Splice Site SelectionJournal of Biological Chemistry2003106
34Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancerNpj Breast Cancer2020106
35Genomic alterations associated with malignancy in head and neck cancer1998103
36Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in MelanomaCancer Cell2018103
37Ribozyme-mediated telomerase inhibition induces immediate cell loss but not telomere shortening in ovarian cancer cellsCancer Gene Therapy2001101
38Chromosomal imbalances of primary and metastatic lung adenocarcinomasJournal of Pathology2002101
39Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of SagopiloneCancer Research2008101
40Utility of 123C3 monoclonal antibody against CD56 (NCAM) for the diagnosis of small cell carcinomas on paraffin sectionsHuman Pathology1997100
41Machine learning analysis of DNA methylation profiles distinguishes primary lung squamous cell carcinomas from head and neck metastasesScience Translational Medicine2019100
42Reversal of breast cancer resistance protein-mediated drug resistance by tryprostatin AInternational Journal of Cancer200399
43DFNA5 (ICERE-1) contributes to acquired etoposide resistance in melanoma cellsFEBS Letters200197
44Enhanced exposure of phosphatidylserine in human gastric carcinoma cells overexpressing the half-size ABC transporter BCRP (ABCG2)Biochemical Journal200394
45Classical and noncanonical functions of miRNAs in cancersTrends in Genetics202294
46Ribozyme cleavage of telomerase mRNA sensitizes breast epithelial cells to inhibitors of topoisomeraseCancer Research200191
47Induction of G0/G1 cell cycle arrest in ovarian carcinoma cells by the anti-inflammatory drug NS-398, but not by COX-2-specific RNA interferenceOncogene200390
48Telomere Length As a Marker of Oxidative Stress in Primary Human Fibroblast CulturesAnnals of the New York Academy of Sciences200087
49Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene mgmtInternational Journal of Cancer200182
50Transport of phosphatidylserine via MDR1 (multidrug resistance 1)P-glycoprotein in a human gastric carcinoma cell lineBiochemical Journal200279