| # | Title | Journal | Year | Citations |
|---|
| 1 | Cisplatin Nephrotoxicity: A Review | American Journal of the Medical Sciences | 2007 | 1,035 |
| 2 | New insights into the genetic etiology of Alzheimer’s disease and related dementias | Nature Genetics | 2022 | 700 |
| 3 | Frontotemporal dementia and its subtypes: a genome-wide association study | Lancet Neurology, The | 2014 | 302 |
| 4 | The Effect of Short-Term Hyperglycemia on the Innate Immune System | American Journal of the Medical Sciences | 2016 | 279 |
| 5 | Atopic Dermatitis: Pathophysiology | Advances in Experimental Medicine and Biology | 2017 | 273 |
| 6 | A comprehensive review and update on ulcerative colitis, | Disease-a-Month | 2019 | 264 |
| 7 | Amelioration of metabolic acidosis in patients with low GFR reduced kidney endothelin production and kidney injury, and better preserved GFR | Kidney International | 2010 | 251 |
| 8 | Vasopressin for Cardiac Arrest | Archives of Internal Medicine | 2005 | 233 |
| 9 | Proton Pump Inhibitors and Risk of Fracture: A Systematic Review and Meta-Analysis of Observational Studies | American Journal of Gastroenterology | 2011 | 230 |
| 10 | Common Causes of Troponin Elevations in the Absence of Acute Myocardial Infarction | Chest | 2004 | 218 |
| 11 | FTD and ALS: A Tale of Two Diseases | Current Alzheimer Research | 2011 | 213 |
| 12 | Antiphospholipid antibodies associated with recurrent pregnancy loss: Prospective, multicenter, controlled pilot study comparing treatment with low-molecular-weight heparin versus unfractionated heparin | Fertility and Sterility | 2005 | 203 |
| 13 | Role of Phytochemicals in Cancer Prevention | International Journal of Molecular Sciences | 2019 | 202 |
| 14 | Diabetic Nephropathy Is Associated with Oxidative Stress and Decreased Renal Nitric Oxide Production | Journal of the American Society of Nephrology: JASN | 2007 | 180 |
| 15 | Synaptic basis of Alzheimer’s disease: Focus on synaptic amyloid beta, P-tau and mitochondria | Ageing Research Reviews | 2021 | 160 |
| 16 | Defective mitophagy in Alzheimer’s disease | Ageing Research Reviews | 2020 | 157 |
| 17 | Liver Abnormalities in Cardiac Diseases and Heart Failure | International Journal of Angiology | 2011 | 156 |
| 18 | Gastric Electrical Stimulation Improves Outcomes of Patients With Gastroparesis for up to 10 Years | Clinical Gastroenterology and Hepatology | 2011 | 146 |
| 19 | Synthetic Cannabinoids | American Journal of the Medical Sciences | 2015 | 140 |
| 20 | Management of hand-foot syndrome induced by capecitabine | Journal of Oncology Pharmacy Practice | 2006 | 137 |
| 21 | Chronic perifusion of rat islets with palmitate suppresses glucose-stimulated insulin release. | Endocrinology | 1993 | 133 |
| 22 | Treatment of Kounis syndrome | International Journal of Cardiology | 2010 | 133 |
| 23 | Crohn’s disease and the mycobacterioses: A quarter century later. Causation or simple association? | Critical Reviews in Microbiology | 2012 | 129 |
| 24 | Dietary protein causes a decline in the glomerular filtration rate of the remnant kidney mediated by metabolic acidosis and endothelin receptors | Kidney International | 2008 | 127 |
| 25 | Cigarette smoking and increased urine albumin excretion are interrelated predictors of nephropathy progression in type 2 diabetes | American Journal of Kidney Diseases | 2003 | 126 |
| 26 | Efficacy and Safety of Relamorelin in Diabetics With Symptoms of Gastroparesis: A Randomized, Placebo-Controlled Study | Gastroenterology | 2017 | 125 |
| 27 | Cardiovascular Toxicities of Immune Checkpoint Inhibitors | Journal of the American College of Cardiology | 2019 | 124 |
| 28 | Cardiac Vasoplegia Syndrome: Pathophysiology, Risk Factors and Treatment | American Journal of the Medical Sciences | 2015 | 122 |
| 29 | Receptor mediated uptake of paclitaxel from a synthetic high density lipoprotein nanocarrier | Journal of Drug Targeting | 2010 | 117 |
| 30 | Dumping Syndrome: A Review of the Current Concepts of Pathophysiology, Diagnosis, and Treatment | Digestive Diseases and Sciences | 2016 | 114 |
| 31 | Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies | PLoS Medicine | 2018 | 111 |
| 32 | FAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cells | BMC Genomics | 2005 | 108 |
| 33 | The most common type of FTLD-FUS (aFTLD-U) is associated with a distinct clinical form of frontotemporal dementia but is not related to mutations in the FUS gene | Acta Neuropathologica | 2011 | 108 |
| 34 | Obstructive Sleep Apnea and Respiratory Complications Associated with Vagus Nerve Stimulators | Journal of Clinical Sleep Medicine | 2011 | 107 |
| 35 | Meta-Analysis of Left Ventricular Hypertrophy and Sustained Arrhythmias | American Journal of Cardiology | 2014 | 107 |
| 36 | Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases | Journal of Neurology, Neurosurgery and Psychiatry | 2017 | 107 |
| 37 | Cigarette smoking predicts faster progression of type 2 established diabetic nephropathy despite ACE inhibition | American Journal of Kidney Diseases | 2002 | 106 |
| 38 | Patterns of Morbidity and Mortality in Typhoid Fever Dependent on Age and Gender: Review of 552 Hopitalized Patients with Diarrhea | Clinical Infectious Diseases | 1991 | 105 |
| 39 | A critical evaluation of neuroprotective and neurodegenerative MicroRNAs in Alzheimer's disease | Biochemical and Biophysical Research Communications | 2017 | 105 |
| 40 | Infections Caused byKluyveraSpecies in Humans | Clinical Infectious Diseases | 2001 | 104 |
| 41 | Dynamics of Dynamin-Related Protein 1 in Alzheimer’s Disease and Other Neurodegenerative Diseases | Cells | 2019 | 104 |
| 42 | Portopulmonary hypertension and hepatopulmonary syndrome: a clinician-oriented overview | European Respiratory Review | 2012 | 97 |
| 43 | Bicarbonate Therapy in Severe Metabolic Acidosis | Journal of the American Society of Nephrology: JASN | 2009 | 96 |
| 44 | Physiology of Endothelin and the Kidney | | 2011 | 96 |
| 45 | Gastric electrical stimulation with Enterra therapy improves symptoms of idiopathic gastroparesis | Neurogastroenterology and Motility | 2013 | 95 |
| 46 | Phase 2b, randomized, double‐blind 12‐week studies of TZP‐102, a ghrelin receptor agonist for diabetic gastroparesis | Neurogastroenterology and Motility | 2013 | 94 |
| 47 | The Effect of Pregnancy on Renal Function: Physiology and Pathophysiology | American Journal of the Medical Sciences | 1992 | 92 |
| 48 | Heart Failure in Hispanics | Journal of the American College of Cardiology | 2009 | 91 |
| 49 | Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia | Acta Neuropathologica | 2017 | 90 |
| 50 | Dietary protein induces endothelin-mediated kidney injury through enhanced intrinsic acid production | Kidney International | 2007 | 88 |
