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Top Articles

#TitleJournalYearCitations
1Cancer stem cells in glioblastomaGenes and Development20151,248
2Glioblastoma Stem Cells Generate Vascular Pericytes to Support Vessel Function and Tumor GrowthCell2013729
3Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growthNature Cell Biology2015716
4The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotypeCell Cycle2009708
5Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like CellsCancer Cell2013665
6Integrin Alpha 6 Regulates Glioblastoma Stem CellsCell Stem Cell2010597
7Notch Promotes Radioresistance of Glioma Stem Cells  Stem Cells2010505
8A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In VivoCancer Research2016453
9Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptakeNature Neuroscience2013408
10Cancer Stem Cells: The Architects of the Tumor EcosystemCell Stem Cell2019407
11Hypoxia inducible factors in cancer stem cellsBritish Journal of Cancer2010392
12High-speed coherent Raman fingerprint imaging of biological tissuesNature Photonics2014358
13Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor GrowthStem Cells2009300
14Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17AJournal of Experimental Medicine2013288
15Glioma Stem Cell Proliferation and Tumor Growth Are Promoted by Nitric Oxide Synthase-2Cell2011280
16Targeting glioma stem cells through combined BMI1 and EZH2 inhibitionNature Medicine2017279
17The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variantsActa Neuropathologica2017271
18Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreasProceedings of the National Academy of Sciences of the United States of America2010264
19Preferential Iron Trafficking Characterizes Glioblastoma Stem-like CellsCancer Cell2015249
20Spatiotemporal Evolution of the Primary Glioblastoma GenomeCancer Cell2015242
21N-methyladenine DNA Modification in GlioblastomaCell2018236
22Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3Cancer Cell2011233
23Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growthNature Communications2017219
24Deadly Teamwork: Neural Cancer Stem Cells and the Tumor MicroenvironmentCell Stem Cell2011218
25The FDA-approved drug sofosbuvir inhibits Zika virus infectionAntiviral Research2017217
26Cancer stem cells in glioblastoma—molecular signaling and therapeutic targetingProtein and Cell2010204
27WNT signaling in glioblastoma and therapeutic opportunitiesLaboratory Investigation2016200
28Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune EvasionStem Cells2016189
29AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem CellsCell Stem Cell2018189
30Patient-Specific Orthotopic Glioblastoma Xenograft Models Recapitulate the Histopathology and Biology of Human Glioblastomas In SituCell Reports2013186
31Cancer Stem Cell-Specific Scavenger Receptor CD36 Drives Glioblastoma ProgressionStem Cells2014182
32Potential therapeutic implications of cancer stem cells in glioblastomaBiochemical Pharmacology2010179
33Zika virus has oncolytic activity against glioblastoma stem cellsJournal of Experimental Medicine2017179
34Cancer stem cellsMedicine (United States)2016176
35Therapeutic targeting of ependymoma as informed by oncogenic enhancer profilingNature2018170
36Elevated invasive potential of glioblastoma stem cellsBiochemical and Biophysical Research Communications2011168
37Targeting Glioma Stem Cell-Derived Pericytes Disrupts the Blood-Tumor Barrier and Improves Chemotherapeutic EfficacyCell Stem Cell2017168
38Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisionsCell Death and Disease2011166
39Brain tumor stem cells: Molecular characteristics and their impact on therapyMolecular Aspects of Medicine2014164
40EZH2 Protects Glioma Stem Cells from Radiation-Induced Cell Death in a MELK/FOXM1-Dependent MannerStem Cell Reports2015159
41Transcription elongation factors represent in vivo cancer dependencies in glioblastomaNature2017156
42Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival of glioblastoma-initiating cellsCell Death and Differentiation2014152
43L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1EMBO Journal2011146
44Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like CellsCell Reports2015146
45Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapyNature Genetics2018145
46Continuous Delivery of Stromal Cell-Derived Factor-1 from Alginate Scaffolds Accelerates Wound HealingCell Transplantation2010143
47Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cellsNature Cell Biology2011139
48EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell propertiesOncogene2015139
49Wnt activation is implicated in glioblastoma radioresistanceLaboratory Investigation2012135
50Transcription Factor Glis3, a Novel Critical Player in the Regulation of Pancreatic β-Cell Development and Insulin Gene ExpressionMolecular and Cellular Biology2009133