| # | Title | Journal | Year | Citations |
|---|
| 1 | Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles | European Journal of Medicinal Chemistry | 2007 | 261 |
| 2 | Angiogenesis inhibitors in cancer therapy: mechanistic perspective on classification and treatment rationales | British Journal of Pharmacology | 2013 | 202 |
| 3 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives | European Journal of Medicinal Chemistry | 2010 | 161 |
| 4 | Protective effects of propolis and thymoquinone on development of atherosclerosis in cholesterol-fed rabbits | Archives of Pharmacal Research | 2010 | 126 |
| 5 | Comparative effects of curcumin and resveratrol on aflatoxin B1-induced liver injury in rats | Archives of Toxicology | 2010 | 114 |
| 6 | Angiotensin (1-7) Receptor Antagonism Equalizes Angiotensin II–Induced Hypertension in Male and Female Spontaneously Hypertensive Rats | Hypertension | 2010 | 106 |
| 7 | Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer | British Journal of Cancer | 2019 | 86 |
| 8 | Synthesis, Antimicrobial, and Anti-inflammatory Activities of Novel 5-(1-Adamantyl)-4-arylideneamino-3-mercapto-1,2,4-triazoles and Related Derivatives | Molecules | 2010 | 82 |
| 9 | Crocin mediated amelioration of oxidative burden and inflammatory cascade suppresses diabetic nephropathy progression in diabetic rats | Chemico-Biological Interactions | 2018 | 80 |
| 10 | Pristimerin protects against doxorubicin-induced cardiotoxicity and fibrosis through modulation of Nrf2 and MAPK/NF-kB signaling pathways | Cancer Management and Research | 2019 | 80 |
| 11 | Celastrol ameliorates murine colitis via modulating oxidative stress, inflammatory cytokines and intestinal homeostasis | Chemico-Biological Interactions | 2014 | 75 |
| 12 | Targeting Nrf2/HO-1 signaling by crocin: Role in attenuation of AA-induced ulcerative colitis in rats | Biomedicine and Pharmacotherapy | 2019 | 68 |
| 13 | Comparative evaluation of anti-inflammatory properties of thymoquinone and curcumin using an asthmatic murine model | International Immunopharmacology | 2011 | 67 |
| 14 | Comparison of imatinib, nilotinib and silymarin in the treatment of carbon tetrachloride-induced hepatic oxidative stress, injury and fibrosis | Toxicology and Applied Pharmacology | 2011 | 66 |
| 15 | Deletion of soluble epoxide hydrolase gene improves renal endothelial function and reduces renal inflammation and injury in streptozotocin-induced type 1 diabetes | American Journal of Physiology - Regulatory Integrative and Comparative Physiology | 2011 | 65 |
| 16 | Crocin protects against doxorubicin-induced myocardial toxicity in rats through down-regulation of inflammatory and apoptic pathways | Chemico-Biological Interactions | 2016 | 65 |
| 17 | Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension | Hypertension | 2016 | 65 |
| 18 | Nifuroxazide, a STAT3 inhibitor, mitigates inflammatory burden and protects against diabetes-induced nephropathy in rats | Chemico-Biological Interactions | 2018 | 60 |
| 19 | Pivotal role of Acitretin nanovesicular gel for effective treatment of psoriasis: ex vivo–in vivo evaluation study | International Journal of Nanomedicine | 2018 | 60 |
| 20 | Protective role of thymoquinone against liver damage induced by tamoxifen in female rats | Canadian Journal of Physiology and Pharmacology | 2014 | 51 |
| 21 | Polymeric micelles for potentiated antiulcer and anticancer activities of naringin | International Journal of Nanomedicine | 2018 | 51 |
| 22 | Nilotinib counteracts thioacetamide‐induced hepatic oxidative stress and attenuates liver fibrosis progression | Fundamental and Clinical Pharmacology | 2011 | 50 |
| 23 | Purification, characterization and immunogenicity assessment of glutaminase free L-asparaginase from Streptomyces brollosae NEAE-115 | BMC Pharmacology & Toxicology | 2018 | 50 |
| 24 | Nilotinib induces apoptosis and autophagic cell death of activated hepatic stellate cells via inhibition of histone deacetylases | Biochimica Et Biophysica Acta - Molecular Cell Research | 2013 | 49 |
| 25 | Renoprotective effect of calycosin in high fat diet-fed/STZ injected rats: Effect on IL-33/ST2 signaling, oxidative stress and fibrosis suppression | Chemico-Biological Interactions | 2020 | 48 |
| 26 | Modified citrus pectin stops progression of liver fibrosis by inhibiting galectin-3 and inducing apoptosis of stellate cells | Canadian Journal of Physiology and Pharmacology | 2016 | 47 |
| 27 | Sitagliptin ameliorates thioacetamide-induced acute liver injury via modulating TLR4/NF-KB signaling pathway in mice | Life Sciences | 2019 | 46 |
| 28 | Nilotinib ameliorates lipopolysaccharide-induced acute lung injury in rats | Toxicology and Applied Pharmacology | 2011 | 45 |
| 29 | Protective effect of allicin against gentamicin-induced nephrotoxicity in rats | International Immunopharmacology | 2015 | 44 |
| 30 | Dapagliflozin attenuates early markers of diabetic nephropathy in fructose-streptozotocin-induced diabetes in rats | Biomedicine and Pharmacotherapy | 2019 | 44 |
| 31 | Effect of betulinic acid on neutrophil recruitment and inflammatory mediator expression in lipopolysaccharide-induced lung inflammation in rats | European Journal of Pharmaceutical Sciences | 2012 | 43 |
| 32 | Nicorandil ameliorates pulmonary inflammation and fibrosis in a rat model of silicosis | International Immunopharmacology | 2018 | 43 |
| 33 | Dimethyl fumarate ameliorates acetaminophen-induced hepatic injury in mice dependent of Nrf-2/HO-1 pathway | Life Sciences | 2019 | 43 |
| 34 | Synthesis and biological evaluation of novel 6-nitro-5-substituted aminoquinolines as local anesthetic and anti-arrhythmic agents: molecular modeling study | Bioorganic and Medicinal Chemistry | 2005 | 42 |
| 35 | Sulforaphane improves dysregulated metabolic profile and inhibits leptin-induced VSMC proliferation: Implications toward suppression of neointima formation after arterial injury in western diet-fed obese mice | Journal of Nutritional Biochemistry | 2016 | 42 |
| 36 | Sulforaphane attenuates the development of atherosclerosis and improves endothelial dysfunction in hypercholesterolemic rabbits | Experimental Biology and Medicine | 2016 | 42 |
| 37 | Implication of Nrf2/HO-1 pathway in the coloprotective effect of coenzyme Q10 against experimentally induced ulcerative colitis | Inflammopharmacology | 2017 | 42 |
| 38 | Comparison of vitamin E, L-carnitine and melatonin in ameliorating carbon tetrachloride and diabetes induced hepatic oxidative stress | Journal of Physiology and Biochemistry | 2009 | 41 |
| 39 | Synthesis, antimicrobial, and anti-inflammatory activity, of novel S-substituted and N-substituted 5-(1-adamantyl)-1,2,4-triazole-3-thiols | Drug Design, Development and Therapy | 2014 | 41 |
| 40 | Tyrosine kinase inhibition effects of novel Pyrazolo[1,5-a]pyrimidines and Pyrido[2,3-d]pyrimidines ligand: Synthesis, biological screening and molecular modeling studies | Bioorganic Chemistry | 2018 | 41 |
| 41 | Design, synthesis, anti-inflammatory activity and molecular docking of potential novel antipyrine and pyrazolone analogs as cyclooxygenase enzyme (COX) inhibitors | Bioorganic and Medicinal Chemistry Letters | 2018 | 40 |
| 42 | Enhanced vasoconstriction and reduced vasorelaxation induced by testosterone and nandrolone in hypercholesterolemic rabbits | Pharmacological Research | 2004 | 38 |
| 43 | Protocatechuic acid exhibits hepatoprotective, vasculoprotective, antioxidant and insulin-like effects in dexamethasone-induced insulin-resistant rats | Biochimie | 2019 | 38 |
| 44 | Thymoquinone attenuates cyclophosphamide-induced pulmonary injury in rats | Inflammopharmacology | 2013 | 37 |
| 45 | Caffeine affects HFD-induced hepatic steatosis by multifactorial intervention | Human and Experimental Toxicology | 2018 | 37 |
| 46 | Anticonvulsant and Neurotoxic Activities of Twelve Analogues of Valproic Acid | Journal of Pharmaceutical Sciences | 1993 | 36 |
| 47 | Febuxostat protects rats against lipopolysaccharide-induced lung inflammation in a dose-dependent manner | Naunyn-Schmiedeberg's Archives of Pharmacology | 2016 | 36 |
| 48 | Cinnamaldehyde ameliorates STZ-induced rat diabetes through modulation of IRS1/PI3K/AKT2 pathway and AGEs/RAGE interaction | Naunyn-Schmiedeberg's Archives of Pharmacology | 2019 | 36 |
| 49 | Tracking anti‐fibrotic pathways of nilotinib and imatinib in experimentally induced liver fibrosis: An insight | Clinical and Experimental Pharmacology and Physiology | 2014 | 35 |
| 50 | Agmatine attenuates rhabdomyolysis-induced acute kidney injury in rats in a dose dependent manner | Life Sciences | 2018 | 35 |
