# | Title | Journal | Year | Citations |
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1 | Positively charged nanoparticles for improving the oral bioavailability of cyclosporin-A | International Journal of Pharmaceutics | 2002 | 331 |
2 | The Genus Enterococcus: Between Probiotic Potential and Safety Concerns—An Update | Frontiers in Microbiology | 2018 | 328 |
3 | Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles | European Journal of Medicinal Chemistry | 2007 | 261 |
4 | Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: Molecular docking study | European Journal of Medicinal Chemistry | 2010 | 207 |
5 | Angiogenesis inhibitors in cancer therapy: mechanistic perspective on classification and treatment rationales | British Journal of Pharmacology | 2013 | 202 |
6 | Pyrido [2, 3-d]pyrimidines and Pyrimido[5′, 4′:5, 6]pyrido[2, 3-d]pyrimidines as New Antiviral Agents: Synthesis and Biological Activity | Archiv Der Pharmazie | 2002 | 197 |
7 | Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 174 |
8 | Synthesis and antitumor evaluation of some new 1,3,4-oxadiazole-based heterocycles | European Journal of Medicinal Chemistry | 2012 | 170 |
9 | New Crinine-Type Alkaloids with Inhibitory Effect on Induction of Inducible Nitric Oxide Synthase fromCrinum yemense | Journal of Natural Products | 2004 | 164 |
10 | Retinal Microglial Activation and Inflammation Induced by Amadori-Glycated Albumin in a Rat Model of Diabetes | Diabetes | 2011 | 162 |
11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives | European Journal of Medicinal Chemistry | 2010 | 161 |
12 | Melatonin, Serotonin, and Tryptamine in Some Egyptian Food and Medicinal Plants | Journal of Medicinal Food | 2002 | 157 |
13 | Diagnostic and prognostic value of hematological and immunological markers in COVID-19 infection: A meta-analysis of 6320 patients | PLoS ONE | 2020 | 155 |
14 | Metabolomics of Type 1 and Type 2 Diabetes | International Journal of Molecular Sciences | 2019 | 151 |
15 | Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study | Bioorganic and Medicinal Chemistry | 2011 | 140 |
16 | Aspirin is an efficient inhibitor of quorum sensing, virulence and toxins in Pseudomonas aeruginosa | Microbial Pathogenesis | 2014 | 139 |
17 | Synthesis, biological evaluation and molecular modeling study of pyrazole and pyrazoline derivatives as selective COX-2 inhibitors and anti-inflammatory agents. Part 2 | Bioorganic and Medicinal Chemistry | 2012 | 133 |
18 | Epidemiology of Neonatal Sepsis and Implicated Pathogens: A Study from Egypt | BioMed Research International | 2015 | 133 |
19 | Synthesis and antitumor activity of new sulfonamide derivatives of thiadiazolo[3,2-a]pyrimidines | European Journal of Medicinal Chemistry | 2011 | 132 |
20 | Synthesis of some new pyrimido[2′,1′:2,3]thiazolo[4,5-b]quinoxaline derivatives as anti-inflammatory and analgesic agents | European Journal of Medicinal Chemistry | 2010 | 131 |
21 | Spectrophotometric determination of some fluoroquinolone antibacterials by binary complex formation with xanthene dyes | Il Farmaco | 2004 | 126 |
22 | Protective effects of propolis and thymoquinone on development of atherosclerosis in cholesterol-fed rabbits | Archives of Pharmacal Research | 2010 | 126 |
23 | Synthesis, antimicrobial, antioxidant, anti-hemolytic and cytotoxic evaluation of new imidazole-based heterocycles | European Journal of Medicinal Chemistry | 2011 | 126 |
24 | Non-classical antifolates. Part 2: Synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones | Bioorganic and Medicinal Chemistry | 2010 | 121 |
25 | Comparative effects of curcumin and resveratrol on aflatoxin B1-induced liver injury in rats | Archives of Toxicology | 2010 | 114 |
26 | Synthesis, antimicrobial activity and conformational analysis of novel substituted pyridines: BF3-promoted reaction of hydrazine with 2-alkoxy pyridines | Bioorganic and Medicinal Chemistry | 2004 | 112 |
27 | Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins | Frontiers in Immunology | 2021 | 111 |
28 | Antioxidant and Immunomodulatory Constituents of Henna Leaves | Zeitschrift Fur Naturforschung - Section C Journal of Biosciences | 2004 | 109 |
29 | Angiotensin (1-7) Receptor Antagonism Equalizes Angiotensin II–Induced Hypertension in Male and Female Spontaneously Hypertensive Rats | Hypertension | 2010 | 106 |
30 | Chemical composition and in vitro antimicrobial, insecticidal and antioxidant activities of the essential oils of Mentha pulegium L. and Mentha rotundifolia (L.) Huds growing in Algeria | Industrial Crops and Products | 2016 | 102 |
31 | Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: Anti-inflammatory and analgesic activities | European Journal of Medicinal Chemistry | 2015 | 97 |
32 | Thymoquinone attenuates Doxorubicin-induced nephrotoxicity in rats: Role of Nrf2 and NOX4 | Chemico-Biological Interactions | 2014 | 96 |
33 | Cepharanthine and Piperine ameliorate diabetic nephropathy in rats: role of NF-κB and NLRP3 inflammasome | Life Sciences | 2016 | 96 |
34 | Substituted thiazoles V. Synthesis and antitumor activity of novel thiazolo[2,3-b]quinazoline and pyrido[4,3-d]thiazolo[3,2-a]pyrimidine analogues | European Journal of Medicinal Chemistry | 2012 | 94 |
35 | Curcumin Attenuates Iron Accumulation and Oxidative Stress in the Liver and Spleen of Chronic Iron-Overloaded Rats | PLoS ONE | 2015 | 92 |
36 | Complement-Coagulation Cross-Talk: A Potential Mediator of the Physiological Activation of Complement by Low pH | Frontiers in Immunology | 2015 | 91 |
37 | Cooperative Unfolding of Compact Conformations of the Intrinsically Disordered Protein Osteopontin | Biochemistry | 2013 | 90 |
38 | Effect of interpolymer complex formation of chitosan with pectin or acacia on the release behaviour of chlorpromazine HCl | International Journal of Pharmaceutics | 1993 | 89 |
39 | Alkaloids and Polyketides from Penicillium citrinum, an Endophyte Isolated from the Moroccan Plant Ceratonia siliqua | Journal of Natural Products | 2013 | 87 |
40 | Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer | British Journal of Cancer | 2019 | 86 |
41 | Association of cardiac biomarkers and comorbidities with increased mortality, severity, and cardiac injury in COVID‐19 patients: A meta‐regression and decision tree analysis | Journal of Medical Virology | 2020 | 83 |
42 | Synthesis, Antimicrobial, and Anti-inflammatory Activities of Novel 5-(1-Adamantyl)-4-arylideneamino-3-mercapto-1,2,4-triazoles and Related Derivatives | Molecules | 2010 | 82 |
43 | Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibitory activities and molecular docking studies of substituted 2-mercapto-4(3H)-quinazolinones | European Journal of Medicinal Chemistry | 2016 | 81 |
44 | Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents | European Journal of Medicinal Chemistry | 2019 | 81 |
45 | Immunomodulatory Triterpenoids from the Oleogum Resin of Boswellia carterii Birdwood | Zeitschrift Fur Naturforschung - Section C Journal of Biosciences | 2003 | 80 |
46 | Novel role of curcumin combined with bone marrow transplantation in reversing experimental diabetes: Effects on pancreatic islet regeneration, oxidative stress, and inflammatory cytokines | European Journal of Pharmacology | 2011 | 80 |
47 | Sodium ascorbate as a quorum sensing inhibitor of Pseudomonas aeruginosa | Journal of Applied Microbiology | 2014 | 80 |
48 | Micellar Liquid Chromatography from Green Analysis Perspective | Open Chemistry | 2015 | 80 |
49 | Metabolites from the Fungal Endophyte Aspergillus austroafricanus in Axenic Culture and in Fungal–Bacterial Mixed Cultures | Journal of Natural Products | 2016 | 80 |
50 | Crocin mediated amelioration of oxidative burden and inflammatory cascade suppresses diabetic nephropathy progression in diabetic rats | Chemico-Biological Interactions | 2018 | 80 |