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Top Articles

#TitleJournalYearCitations
1Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life SpanCell Metabolism20081,060
2Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression.Circulation Research1994837
3Distinct Narcolepsy Syndromes in Orexin Receptor-2 and Orexin Null MiceNeuron2003603
4Aging-Induced Phenotypic Changes and Oxidative Stress Impair Coronary Arteriolar FunctionCirculation Research2002511
5Oxidant Mechanisms in Renal Injury and DiseaseAntioxidants and Redox Signaling2016468
6Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2American Journal of Physiology - Heart and Circulatory Physiology2010457
7Interactions of Oxidants With Vascular Signaling SystemsArteriosclerosis, Thrombosis, and Vascular Biology2000434
8Mechanisms of Vascular Aging: New PerspectivesJournals of Gerontology - Series A Biological Sciences and Medical Sciences2010429
9Function of Specific K+ Channels in Sustained High-Frequency Firing of Fast-Spiking Neocortical InterneuronsJournal of Neurophysiology1999423
10The spread of Na+ spikes determines the pattern of dendritic Ca2+ entry into hippocampal neuronsNature1992397
11Inflammation and endothelial dysfunction during aging: role of NF-κBJournal of Applied Physiology2008388
12Resveratrol induces mitochondrial biogenesis in endothelial cellsAmerican Journal of Physiology - Heart and Circulatory Physiology2009378
13Peripheral afferent inputs to the forelimb area of the monkey motor cortex: Input-output relationsExperimental Brain Research1972366
14Topographical organization of cortical efferent zones projecting to distal forelimb muscles in the monkeyExperimental Brain Research1972346
15Programmed Myocyte Cell Death Affects the Viable Myocardium after Infarction in RatsExperimental Cell Research1996323
16Synergistic Release of Ca2+ from IP3-Sensitive Stores Evoked by Synaptic Activation of mGluRs Paired with Backpropagating Action PotentialsNeuron1999310
17Impaired Myocardial Fatty Acid Oxidation and Reduced Protein Expression of Retinoid X Receptor-α in Pacing-Induced Heart FailureCirculation2002306
18Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cellsAmerican Journal of Physiology - Heart and Circulatory Physiology2009300
19eNOS uncoupling and endothelial dysfunction in aged vesselsAmerican Journal of Physiology - Heart and Circulatory Physiology2009297
20Role of nitric oxide in the regulation of oxygen consumption in conscious dogs.Circulation Research1994293
21NADH oxidoreductase is a major source of superoxide anion in bovine coronary artery endotheliumAmerican Journal of Physiology - Heart and Circulatory Physiology1994289
22Reduced Nitric Oxide Production and Altered Myocardial Metabolism During the Decompensation of Pacing-Induced Heart Failure in the Conscious DogCirculation Research1998289
23Increased mitochondrial H2O2 production promotes endothelial NF-κB activation in aged rat arteriesAmerican Journal of Physiology - Heart and Circulatory Physiology2007288
24Role of shear stress and endothelial prostaglandins in flow- and viscosity-induced dilation of arterioles in vitro.Circulation Research1993287
25Chronic exercise enhances endothelium-mediated dilation of epicardial coronary artery in conscious dogs.Circulation Research1993275
26Direct and Indirect Excitation of Laterodorsal Tegmental Neurons by Hypocretin/Orexin Peptides: Implications for Wakefulness and NarcolepsyJournal of Neuroscience2002271
27Calcium transients evoked by climbing fiber and parallel fiber synaptic inputs in guinea pig cerebellar Purkinje neuronsJournal of Neurophysiology1992265
28Amlodipine Releases Nitric Oxide From Canine Coronary MicrovesselsCirculation1998262
29Functional heterogeneity of vascular endothelial cellsBiochemical Pharmacology1987259
30Aging‐induced proinflammatory shift in cytokine expression profile in rat coronary arteriesFASEB Journal2003254
31Increased Superoxide Production in Coronary Arteries in HyperhomocysteinemiaArteriosclerosis, Thrombosis, and Vascular Biology2003249
32Resveratrol attenuates TNF-α-induced activation of coronary arterial endothelial cells: role of NF-κB inhibitionAmerican Journal of Physiology - Heart and Circulatory Physiology2006248
33Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterationsAmerican Journal of Physiology - Heart and Circulatory Physiology2008246
34IPSPs modulate spike backpropagation and associated [Ca2+]i changes in the dendrites of hippocampal CA1 pyramidal neuronsJournal of Neurophysiology1996226
35Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: Role of circulating factors and SIRT1Mechanisms of Ageing and Development2009221
36Doxorubicin induced heart failure: Phenotype and molecular mechanismsIJC Heart and Vasculature2016220
37Mechanisms Underlying Caloric Restriction and Lifespan RegulationCirculation Research2008219
38Nitric OxideCirculation1995217
39IPSPs strongly inhibit climbing fiber-activated [Ca2+]i increases in the dendrites of cerebellar Purkinje neuronsJournal of Neuroscience1995211
40Regulation of Bone Morphogenetic Protein-2 Expression in Endothelial CellsCirculation2005210
41Inhibition of coronary artery superoxide dismutase attenuates endothelium-dependent and -independent nitrovasodilator relaxation.Circulation Research1991207
42Nrf2 mediates cancer protection but not prolongevity induced by caloric restrictionProceedings of the National Academy of Sciences of the United States of America2008207
43Mapping calcium transients in the dendrites of Purkinje cells from the guinea‐pig cerebellum in vitro.Journal of Physiology1987206
44Calcium transients in cerebellar Purkinje neurons evoked by intracellular stimulationJournal of Neurophysiology1992206
45Resveratrol increases vascular oxidative stress resistanceAmerican Journal of Physiology - Heart and Circulatory Physiology2007204
46Depression and coronary heart disease: 2018 position paper of the ESC working group on coronary pathophysiology and microcirculationEuropean Heart Journal2020203
47Exercise Training Augments Flow-Dependent Dilation in Rat Skeletal Muscle ArteriolesCirculation Research1995203
48Prostaglandins mediate arteriolar dilation to increased blood flow velocity in skeletal muscle microcirculation.Circulation Research1990201
49High Pressure Induces Superoxide Production in Isolated Arteries Via Protein Kinase C–Dependent Activation of NAD(P)H OxidaseCirculation2003194
50Coronary Kinin Generation Mediates Nitric Oxide Release After Angiotensin Receptor StimulationHypertension1995194