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Top Articles

#TitleJournalYearCitations
1Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's diseaseNeurochemistry International2009438
2What Is New for an Old Molecule? Systematic Review and Recommendations on the Use of ResveratrolPLoS ONE2011375
3DNA PrimasesAnnual Review of Biochemistry2001341
4Differential Effects on Growth, Cell Cycle Arrest, and Induction of Apoptosis by Resveratrol in Human Prostate Cancer Cell LinesExperimental Cell Research1999327
5Mechanism of cardioprotection by resveratrol, a phenolic antioxidant present in red wine (Review)International Journal of Molecular Medicine2001254
6Stress-triggered activation of gene expression in catecholaminergic systems: dynamics of transcriptional eventsTrends in Neurosciences2001253
7Crystal Structure of Quinone Reductase 2 in Complex with Resveratrol†,‡Biochemistry2004219
8ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivoJournal of Experimental Medicine2008219
9Diagnosis of early Lyme disease by polymerase chain reaction amplification and culture of skin biopsies from erythema migrans lesionsJournal of Clinical Microbiology1992218
10Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cellsBiochemical and Biophysical Research Communications2004214
11Astrocyte Glutamine Synthetase: Importance in Hyperammonemic Syndromes and Potential Target for TherapyNeurotherapeutics2010195
12N‐acetylcysteine targets 5 lipoxygenase‐derived, toxic lipids and can synergize with prostaglandin E2 to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in miceAnnals of Neurology2018195
13Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21(WAF1/CIP1), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2Cancer Research1999188
14rRNA gene organization in the Lyme disease spirochete, Borrelia burgdorferiJournal of Bacteriology1992186
15DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosisJournal of Cell Biology2013165
16Central Role of Glutamate Metabolism in the Maintenance of Nitrogen Homeostasis in Normal and Hyperammonemic BrainBiomolecules2016163
17Single intranasal neuropeptide Y infusion attenuates development of PTSD-like symptoms to traumatic stress in ratsNeuroscience2013154
18Disease Severity in a Murine Model of Lyme Borreliosis Is Associated with the Genotype of the InfectingBorrelia burgdorferiSensu Stricto StrainJournal of Infectious Diseases2002147
19Direct Observation of DNA Distortion by the RSC ComplexMolecular Cell2006146
20Resveratrol: a cardioprotective substanceAnnals of the New York Academy of Sciences2011144
21Association of removable partial denture use with oral and systemic healthJournal of Dentistry2011142
22Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis stepEMBO Journal2008140
23Thiosulfoxide (Sulfane) Sulfur: New Chemistry and New Regulatory Roles in BiologyMolecules2014138
24PSI-7851, a Pronucleotide of β- d -2′-Deoxy-2′-Fluoro-2′- C -Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus ReplicationAntimicrobial Agents and Chemotherapy2010137
25Differential control of growth, cell cycle progression, and expression of NF-κB in human breast cancer cells MCF-7, MCF-10A, and MDA-MB-231 by ponicidin and oridonin, diterpenoids from the chinese herb Rabdosia rubescensBiochemical and Biophysical Research Communications2005135
26Impact of Genotypic Variation of Borrelia burgdorferi Sensu Stricto on Kinetics of Dissemination and Severity of Disease in C3H/HeJ MiceInfection and Immunity2001129
27Estradiol Stimulates Gene Expression of Norepinephrine Biosynthetic Enzymes in Rat Locus coeruleusNeuroendocrinology2002128
28Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoterCarcinogenesis2008127
29Reversible and irreversible protein glutathionylation: biological and clinical aspectsExpert Opinion on Drug Metabolism and Toxicology2011127
30Targeting the neuropeptide Y system in stress-related psychiatric disordersNeurobiology of Stress2015127
31Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington diseaseEMBO Molecular Medicine2010124
32The hepatitis C virus NS3 protein: a model RNA helicase and potential drug targetCurrent Issues in Molecular Biology2007119
33Molecular typing of Borrelia burgdorferi sensu lato by PCR-restriction fragment length polymorphism analysisJournal of Clinical Microbiology1995118
34Lysine metabolism in mammalian brain: an update on the importance of recent discoveriesAmino Acids2013117
35Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of TelomeresCell Reports2016113
36Hepatitis C Virus Subgenomic Replicon Requires an Active NS3 RNA HelicaseJournal of Virology2006112
37Induction of tyrosine hydroxylase gene expression by a nonneuronal nonpituitary-mediated mechanism in immobilization stress.Proceedings of the National Academy of Sciences of the United States of America1994110
38RiboflavinAdvances in Nutrition2016110
39A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivoNature Genetics2020110
40Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δDNA Repair2013108
41Mechanism of fenretinide (4-HPR)-induced cell deathApoptosis: an International Journal on Programmed Cell Death2001106
42Inhibition of caspase-3 activity and activation by protein glutathionylationBiochemical Pharmacology2008104
43Regulated expression of the tyrosine hydroxylase gene by membrane depolarization. Identification of the responsive element and possible second messengersJournal of Biological Chemistry1992103
44Activation of Caspase 3 in HL-60 Cells Exposed to Hydrogen PeroxideBiochemical and Biophysical Research Communications1999102
45The Nonstructural Protein 3 Protease/Helicase Requires an Intact Protease Domain to Unwind Duplex RNA EfficientlyJournal of Biological Chemistry200497
46Bacterial topoisomerase I as a target for discovery of antibacterial compoundsNucleic Acids Research200996
47Intranasal neuropeptide Y reverses anxiety and depressive-like behavior impaired by single prolonged stress PTSD modelEuropean Neuropsychopharmacology201496
48Cell death: apoptosis versus necrosis (review)International Journal of Oncology200296
49Immobilization stress elevates gene expression for catecholamine biosynthetic enzymes and some neuropeptides in rat sympathetic ganglia: effects of adrenocorticotropin and glucocorticoids.Endocrinology199694
50Regulation of Tyrosine Hydroxylase and Dopamine ?-Hydroxylase mRNA Levels in Rat Adrenals by a Single and Repeated Immobilization StressJournal of Neurochemistry199292