| # | Title | Journal | Year | Citations |
|---|
| 1 | K + Channel Mutations in Adrenal Aldosterone-Producing Adenomas and Hereditary Hypertension | Science | 2011 | 866 |
| 2 | Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemie myocardium | Journal of Pharmacological Methods | 1985 | 843 |
| 3 | Mineralocorticoid Blockade Reduces Vascular Injury in Stroke-Prone Hypertensive Rats | Hypertension | 1998 | 476 |
| 4 | Potassium Modulates Electrolyte Balance and Blood Pressure through Effects on Distal Cell Voltage and Chloride | Cell Metabolism | 2015 | 353 |
| 5 | Role of Aldosterone in Renal Vascular Injury in Stroke-Prone Hypertensive Rats | Hypertension | 1999 | 305 |
| 6 | Treatment of Obese Diabetic Mice With a Heme Oxygenase Inducer Reduces Visceral and Subcutaneous Adiposity, Increases Adiponectin Levels, and Improves Insulin Sensitivity and Glucose Tolerance | Diabetes | 2008 | 293 |
| 7 | Cytochrome P-450 Metabolism of Arachidonic Acid | Annual Review of Pharmacology and Toxicology | 1991 | 286 |
| 8 | A Role for the Mouse 12/15-Lipoxygenase Pathway in Promoting Epithelial Wound Healing and Host Defense | Journal of Biological Chemistry | 2005 | 274 |
| 9 | Treatment with tin prevents the development of hypertension in spontaneously hypertensive rats | Science | 1989 | 265 |
| 10 | Hypertension with or without adrenal hyperplasia due to different inherited mutations in the potassium channel KCNJ5 | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 261 |
| 11 | Small Interfering RNA Targeting Heme Oxygenase-1 Enhances Ischemia-Reperfusion-induced Lung Apoptosis | Journal of Biological Chemistry | 2004 | 230 |
| 12 | Antioxidant mechanism of heme oxygenase-1 involves an increase in superoxide dismutase and catalase in experimental diabetes | American Journal of Physiology - Heart and Circulatory Physiology | 2005 | 228 |
| 13 | Effect of cytochrome P450 arachidonate metabolites on ion transport in rabbit kidney loop of Henle | Science | 1991 | 211 |
| 14 | Gene transfer of human heme oxygenase into coronary endothelial cells potentially promotes angiogenesis | Journal of Cellular Biochemistry | 1998 | 207 |
| 15 | Heme Induces the Expression of Adhesion Molecules ICAM-1, VCAM-1, and E Selectin in Vascular Endothelial Cells | Experimental Biology and Medicine | 1997 | 205 |
| 16 | Cytochrome P-450 metabolites mediate extracellular Ca(2+)-induced inhibition of apical K+ channels in the TAL | American Journal of Physiology - Cell Physiology | 1996 | 201 |
| 17 | Cytochrome P450-derived arachidonic acid metabolism in the rat kidney: characterization of selective inhibitors | Journal of Pharmacology and Experimental Therapeutics | 1998 | 195 |
| 18 | Docosahexaenoic acid (DHA) blunts liver injury by conversion to protective lipid mediators: protectin D1 and 17S‐hydroxy‐DHA | FASEB Journal | 2006 | 194 |
| 19 | Heme oxygenase-1 accelerates tumor angiogenesis of human pancreatic cancer | Angiogenesis | 2003 | 191 |
| 20 | RENAL K+CHANNELS: Structure and Function | Annual Review of Physiology | 1997 | 184 |
| 21 | Carbon monoxide of vascular origin attenuates the sensitivity of renal arterial vessels to vasoconstrictors | Journal of Clinical Investigation | 2001 | 171 |
| 22 | 20-Hydroxyeicosatetraenoic Acid Stimulates Nuclear Factor-κB Activation and the Production of Inflammatory Cytokines in Human Endothelial Cells | Journal of Pharmacology and Experimental Therapeutics | 2008 | 169 |
| 23 | A Heme Oxygenase Product, Presumably Carbon Monoxide, Mediates a Vasodepressor Function in Rats | Hypertension | 1995 | 161 |
| 24 | Heme Oxygenase-1 Induction Remodels Adipose Tissue and Improves Insulin Sensitivity in Obesity-Induced Diabetic Rats | Hypertension | 2009 | 160 |
| 25 | Hyperpolarizing Factors | Biochemical Pharmacology | 1997 | 153 |
| 26 | Human Heme Oxygenase-1 Gene Transfer Lowers Blood Pressure and Promotes Growth in Spontaneously Hypertensive Rats | Hypertension | 2001 | 149 |
| 27 | 20-Hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling | American Journal of Physiology - Heart and Circulatory Physiology | 2008 | 149 |
| 28 | Vascular Cytochrome P450 4A Expression and 20-Hydroxyeicosatetraenoic Acid Synthesis Contribute to Endothelial Dysfunction in Androgen-Induced Hypertension | Hypertension | 2007 | 148 |
| 29 | Enalapril prevents stroke and kidney dysfunction in salt-loaded stroke-prone spontaneously hypertensive rats. | Hypertension | 1989 | 145 |
| 30 | Heme Oxygenase-1 Attenuates Glucose-Mediated Cell Growth Arrest and Apoptosis in Human Microvessel Endothelial Cells | Circulation Research | 2003 | 142 |
| 31 | L-4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice | Journal of Lipid Research | 2008 | 142 |
| 32 | Nitric oxide-generating vasodilators inhibit mitogenesis and proliferation of BALBc 3T3 fibroblasts by a cyclic GMP-independent mechanism | Biochemical and Biophysical Research Communications | 1990 | 139 |
| 33 | Natriuretic action of angiotensin(1–7) | British Journal of Pharmacology | 1994 | 137 |
| 34 | KCNJ10 determines the expression of the apical Na-Cl cotransporter (NCC) in the early distal convoluted tubule (DCT1) | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 136 |
| 35 | Regulation of potassium (K) handling in the renal collecting duct | Pflugers Archiv European Journal of Physiology | 2009 | 135 |
| 36 | Potassium Sensing by Renal Distal Tubules Requires Kir4.1 | Journal of the American Society of Nephrology: JASN | 2017 | 133 |
| 37 | Epoxyeicosatrienoic Acid Agonist Rescues the Metabolic Syndrome Phenotype of HO-2-Null Mice | Journal of Pharmacology and Experimental Therapeutics | 2009 | 129 |
| 38 | Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving ‘SIRT1 and PGC-1α’ | Cardiovascular Diabetology | 2018 | 128 |
| 39 | Nitric oxide decreases cytosolic free calcium in Balb/c 3T3 fibroblasts by a cyclic GMP-independent mechanism | Journal of Biological Chemistry | 1991 | 128 |
| 40 | Kinins, nitric oxide, and the hypotensive effect of captopril and ramiprilat in hypertension. | Hypertension | 1992 | 126 |
| 41 | Aldosterone as a Mediator in Cardiovascular Injury | Cardiology in Review | 2002 | 126 |
| 42 | Heme Oxygenase-Mediated Increases in Adiponectin Decrease Fat Content and Inflammatory Cytokines Tumor Necrosis Factor-α and Interleukin-6 in Zucker Rats and Reduce Adipogenesis in Human Mesenchymal Stem Cells | Journal of Pharmacology and Experimental Therapeutics | 2008 | 122 |
| 43 | Carbon monoxide and cerebral microvascular tone in newborn pigs | American Journal of Physiology - Heart and Circulatory Physiology | 1999 | 120 |
| 44 | Metabolism of 20-hydroxyeicosatetraenoic acid by cyclooxygenase. Formation and identification of novel endothelium-dependent vasoconstrictor metabolites | Journal of Biological Chemistry | 1989 | 120 |
| 45 | Angiotensin II releases 20-HETE from rat renal microvessels | American Journal of Physiology - Renal Physiology | 2000 | 115 |
| 46 | Regulation of Cyclooxygenase-2 by Hypoxia and Peroxisome Proliferators in the Corneal Epithelium | Journal of Biological Chemistry | 2000 | 115 |
| 47 | High performance liquid chromatography and UV detection for the separation and quantitation of prostaglandins | Prostaglandins | 1981 | 114 |
| 48 | Cytochrome P450‐dependent effects of bradykinin in the rat heart | British Journal of Pharmacology | 1995 | 113 |
| 49 | Circulating endothelial cells are elevated in patients with type 2 diabetes mellitus independently of HbA1c | Diabetologia | 2005 | 109 |
| 50 | Differential effects of heme oxygenase isoforms on heme mediation of endothelial intracellular adhesion molecule 1 expression | Journal of Pharmacology and Experimental Therapeutics | 1999 | 109 |
