Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence | Cell Reports | 2013 | 177 |
Adenosine-to-inosine RNA editing and human disease | Genome Medicine | 2013 | 167 |
Concurrent MEK2 mutation and BRAF amplification confer resistance to BRAF and MEK inhibitors in melanoma | Cell Reports | 2013 | 141 |
The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis | Science Signaling | 2013 | 114 |
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex | Nature Structural and Molecular Biology | 2013 | 107 |
Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndrome | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 100 |
FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas | Journal of Biological Chemistry | 2013 | 89 |
Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition | Cell Cycle | 2013 | 61 |
Protein isoform-specific validation defines multiple chloride intracellular channel and tropomyosin isoforms as serological biomarkers of ovarian cancer | Journal of Proteomics | 2013 | 55 |
Histone acetyltransferases: Rising ancient counterparts to protein kinases | Biopolymers | 2013 | 54 |
Structure of the human telomeric Stn1-Ten1 capping complex | PLoS ONE | 2013 | 54 |
Molecular basis for oligomeric-DNA binding and episome maintenance by KSHV LANA | PLoS Pathogens | 2013 | 49 |
Structure and mechanism of non-histone protein acetyltransferase enzymes | FEBS Journal | 2013 | 49 |
Architectural organization of the metabolic regulatory enzyme ghrelin O-acyltransferase | Journal of Biological Chemistry | 2013 | 48 |
NF-YA underlies EZH2 upregulation and is essential for proliferation of human epithelial ovarian cancer cells | Molecular Cancer Research | 2013 | 45 |
BRG1 is required for formation of senescence-associated heterochromatin foci induced by oncogenic RAS or BRCA1 loss | Molecular and Cellular Biology | 2013 | 34 |
Implications for the evolution of eukaryotic amino-terminal acetyltransferase (NAT) enzymes from the structure of an archaeal ortholog | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 30 |
Sp100A promotes chromatin decondensation at a cytomegalovirus-promoter-regulated transcription site | Molecular Biology of the Cell | 2013 | 21 |
Role of EZH2 in Epithelial Ovarian Cancer: From Biological Insights to Therapeutic Target | Frontiers in Oncology | 2013 | 16 |
Identification of multiple novel protein biomarkers shed by human serous ovarian tumors into the blood of immunocompromised mice and verified in patient sera | PLoS ONE | 2013 | 15 |
Single cell analysis of RNA-mediated histone H3.3 recruitment to a cytomegalovirus promoter-regulated transcription site | Journal of Biological Chemistry | 2013 | 13 |
New vectors for epitope tagging and gene disruption in Schizosaccharomyces pombe | BioTechniques | 2013 | 11 |
A high-content screening assay for small-molecule modulators of oncogene-induced senescence | Journal of Biomolecular Screening | 2013 | 10 |
Correlates of relative resistance against low-dose rectal simian immunodeficiency virus challenges in peripheral blood mononuclear cells of vaccinated rhesus macaques | Journal of Leukocyte Biology | 2013 | 6 |
Posttranscriptional Gene Regulation by an Editor: ADAR and its Role in RNA Editing | | 2013 | |