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Center for Systems and Computational Biology
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top-articles
Center for Systems and Computational Biology
74
(top 1%)
papers
5.3K
(top 1%)
citations
38
(top 1%)
h
-index
73
(top 1%)
g
-index
78
all documents
5.9K
doc citations
1.2K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers
Nature Medicine
2015
530
2
BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression
Cell Reports
2016
331
3
IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity
Nature
2018
252
4
The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type
Proceedings of the National Academy of Sciences of the United States of America
2012
237
5
NAD+ metabolism governs the proinflammatory senescence-associated secretome
Nature Cell Biology
2019
232
6
Mechanosensing by the Lamina Protects against Nuclear Rupture, DNA Damage, and Cell-Cycle Arrest
Developmental Cell
2019
217
7
Unlinking an lncRNA from Its Associated cis Element
Molecular Cell
2016
216
8
Alternative transcription exceeds alternative splicing in generating the transcriptome diversity of cerebellar development
Genome Research
2011
192
9
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
Proceedings of the National Academy of Sciences of the United States of America
2015
174
10
Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development
Blood
2014
169
11
Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming
Cancer Cell
2016
158
12
Deciphering the human platelet sheddome
Blood
2011
152
13
HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci
Journal of Cell Biology
2016
132
14
BET Bromodomain Inhibition Synergizes with PARP Inhibitor in Epithelial Ovarian Cancer
Cell Reports
2017
130
15
N6-Methylation of Adenosine of
FZD10
mRNA Contributes to PARP Inhibitor Resistance
Cancer Research
2019
127
16
The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis
PLoS Biology
2016
118
17
BET Inhibitors Suppress ALDH Activity by Targeting
ALDH1A1
Super-Enhancer in Ovarian Cancer
Cancer Research
2016
115
18
Peroxiredoxin 6 Phosphorylation and Subsequent Phospholipase A2 Activity Are Required for Agonist-mediated Activation of NADPH Oxidase in Mouse Pulmonary Microvascular Endothelium and Alveolar Macrophages
Journal of Biological Chemistry
2011
114
19
A neuronal network of mitochondrial dynamics regulates metastasis
Nature Communications
2016
112
20
Identification of Sensitive Serum microRNA Biomarkers for Radiation Biodosimetry
PLoS ONE
2013
111
21
Alternative transcription and alternative splicing in cancer
2012
107
22
The H3K27me3 Demethylase dUTX Is a Suppressor of Notch- and Rb-Dependent Tumors in
Drosophila
Molecular and Cellular Biology
2010
106
23
Identification of secreted proteins that reflect autophagy dynamics within tumor cells
Autophagy
2015
101
24
IRE1α–XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain
Science
2019
91
25
Satb1 Overexpression Drives Tumor-Promoting Activities in Cancer-Associated Dendritic Cells
Cell Reports
2016
89
26
Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis
Genome Research
2014
88
27
Follicle-Stimulating Hormone Receptor Is Expressed by Most Ovarian Cancer Subtypes and Is a Safe and Effective Immunotherapeutic Target
Clinical Cancer Research
2017
77
28
Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer
Cell Reports
2018
77
29
CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity
Nature Communications
2018
72
30
Frontline Science: Microbiota reconstitution restores intestinal integrity after cisplatin therapy
Journal of Leukocyte Biology
2018
72
31
Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia
PLoS ONE
2013
60
32
Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer
Matrix Biology
2018
54
33
Mammalian Tropomodulins Nucleate Actin Polymerization via Their Actin Monomer Binding and Filament Pointed End-capping Activities*
Journal of Biological Chemistry
2010
53
34
Systematic Discovery of Ectopic Pregnancy Serum Biomarkers Using 3-D Protein Profiling Coupled with Label-free Quantitation
Journal of Proteome Research
2011
51
35
The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cells
Science Signaling
2020
51
36
Syntaphilin Ubiquitination Regulates Mitochondrial Dynamics and Tumor Cell Movements
Cancer Research
2018
47
37
Molecular classification of breast phyllodes tumors: validation of the histologic grading scheme and insights into malignant progression
Breast Cancer Research and Treatment
2011
45
38
Childhood lead exposure and uptake in teeth in the Cleveland area during the era of leaded gasoline
Science of the Total Environment
2010
41
39
Peroxiredoxin 6 homodimerization and heterodimerization with glutathione S-transferase pi are required for its peroxidase but not phospholipase A2 activity
Free Radical Biology and Medicine
2016
40
40
ARID1A promotes genomic stability through protecting telomere cohesion
Nature Communications
2019
40
41
SWI/SNF catalytic subunits’ switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells
Nature Communications
2018
38
42
Uncovering Thousands of New Peptides with Sequence-Mask-Search Hybrid De Novo Peptide Sequencing Framework
Molecular and Cellular Proteomics
2019
36
43
Increased Phospholipase A
2
Activity with Phosphorylation of Peroxiredoxin 6 Requires a Conformational Change in the Protein
Biochemistry
2012
35
44
ARID1A spatially partitions interphase chromosomes
Science Advances
2019
35
45
MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer
Cancer Research
2019
34
46
A label-free proteome analysis strategy for identifying quantitative changes in erythrocyte membranes induced by red cell disorders
Journal of Proteomics
2012
33
47
HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors
Cancer Research
2016
33
48
Akt phosphorylation of mitochondrial Lonp1 protease enables oxidative metabolism and advanced tumor traits
Oncogene
2019
32
49
BAMM (BRAF Autophagy and MEK Inhibition in Melanoma): A Phase I/II Trial of Dabrafenib, Trametinib, and Hydroxychloroquine in Advanced
BRAFV600
-mutant Melanoma
Clinical Cancer Research
2022
32
50
Myc Regulation of a Mitochondrial Trafficking Network Mediates Tumor Cell Invasion and Metastasis
Molecular and Cellular Biology
2019
31
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