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Top Articles

#TitleJournalYearCitations
1Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancersNature Medicine2015530
2BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 ExpressionCell Reports2016331
3IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activityNature2018252
4The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor typeProceedings of the National Academy of Sciences of the United States of America2012237
5NAD+ metabolism governs the proinflammatory senescence-associated secretomeNature Cell Biology2019232
6Mechanosensing by the Lamina Protects against Nuclear Rupture, DNA Damage, and Cell-Cycle ArrestDevelopmental Cell2019217
7Unlinking an lncRNA from Its Associated cis ElementMolecular Cell2016216
8Alternative transcription exceeds alternative splicing in generating the transcriptome diversity of cerebellar developmentGenome Research2011192
9PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasionProceedings of the National Academy of Sciences of the United States of America2015174
10Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic developmentBlood2014169
11Mitochondrial Akt Regulation of Hypoxic Tumor ReprogrammingCancer Cell2016158
12Deciphering the human platelet sheddomeBlood2011152
13HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene lociJournal of Cell Biology2016132
14BET Bromodomain Inhibition Synergizes with PARP Inhibitor in Epithelial Ovarian CancerCell Reports2017130
15N6-Methylation of Adenosine of FZD10 mRNA Contributes to PARP Inhibitor ResistanceCancer Research2019127
16The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and MetastasisPLoS Biology2016118
17BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian CancerCancer Research2016115
18Peroxiredoxin 6 Phosphorylation and Subsequent Phospholipase A2 Activity Are Required for Agonist-mediated Activation of NADPH Oxidase in Mouse Pulmonary Microvascular Endothelium and Alveolar MacrophagesJournal of Biological Chemistry2011114
19A neuronal network of mitochondrial dynamics regulates metastasisNature Communications2016112
20Identification of Sensitive Serum microRNA Biomarkers for Radiation BiodosimetryPLoS ONE2013111
21Alternative transcription and alternative splicing in cancer2012107
22The H3K27me3 Demethylase dUTX Is a Suppressor of Notch- and Rb-Dependent Tumors in DrosophilaMolecular and Cellular Biology2010106
23Identification of secreted proteins that reflect autophagy dynamics within tumor cellsAutophagy2015101
24IRE1α–XBP1 signaling in leukocytes controls prostaglandin biosynthesis and painScience201991
25Satb1 Overexpression Drives Tumor-Promoting Activities in Cancer-Associated Dendritic CellsCell Reports201689
26Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesisGenome Research201488
27Follicle-Stimulating Hormone Receptor Is Expressed by Most Ovarian Cancer Subtypes and Is a Safe and Effective Immunotherapeutic TargetClinical Cancer Research201777
28Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian CancerCell Reports201877
29CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activityNature Communications201872
30Frontline Science: Microbiota reconstitution restores intestinal integrity after cisplatin therapyJournal of Leukocyte Biology201872
31Global Identification of EVI1 Target Genes in Acute Myeloid LeukemiaPLoS ONE201360
32Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancerMatrix Biology201854
33Mammalian Tropomodulins Nucleate Actin Polymerization via Their Actin Monomer Binding and Filament Pointed End-capping Activities*Journal of Biological Chemistry201053
34Systematic Discovery of Ectopic Pregnancy Serum Biomarkers Using 3-D Protein Profiling Coupled with Label-free QuantitationJournal of Proteome Research201151
35The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cellsScience Signaling202051
36Syntaphilin Ubiquitination Regulates Mitochondrial Dynamics and Tumor Cell MovementsCancer Research201847
37Molecular classification of breast phyllodes tumors: validation of the histologic grading scheme and insights into malignant progressionBreast Cancer Research and Treatment201145
38Childhood lead exposure and uptake in teeth in the Cleveland area during the era of leaded gasolineScience of the Total Environment201041
39Peroxiredoxin 6 homodimerization and heterodimerization with glutathione S-transferase pi are required for its peroxidase but not phospholipase A2 activityFree Radical Biology and Medicine201640
40ARID1A promotes genomic stability through protecting telomere cohesionNature Communications201940
41SWI/SNF catalytic subunits’ switch drives resistance to EZH2 inhibitors in ARID1A-mutated cellsNature Communications201838
42Uncovering Thousands of New Peptides with Sequence-Mask-Search Hybrid De Novo Peptide Sequencing FrameworkMolecular and Cellular Proteomics201936
43Increased Phospholipase A2 Activity with Phosphorylation of Peroxiredoxin 6 Requires a Conformational Change in the ProteinBiochemistry201235
44ARID1A spatially partitions interphase chromosomesScience Advances201935
45MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in CancerCancer Research201934
46A label-free proteome analysis strategy for identifying quantitative changes in erythrocyte membranes induced by red cell disordersJournal of Proteomics201233
47HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF InhibitorsCancer Research201633
48Akt phosphorylation of mitochondrial Lonp1 protease enables oxidative metabolism and advanced tumor traitsOncogene201932
49BAMM (BRAF Autophagy and MEK Inhibition in Melanoma): A Phase I/II Trial of Dabrafenib, Trametinib, and Hydroxychloroquine in Advanced BRAFV600-mutant MelanomaClinical Cancer Research202232
50Myc Regulation of a Mitochondrial Trafficking Network Mediates Tumor Cell Invasion and MetastasisMolecular and Cellular Biology201931