| # | Title | Journal | Year | Citations |
|---|
| 1 | MMEJ repair of double-strand breaks (director’s cut): deleted sequences and alternative endings | Trends in Genetics | 2008 | 841 |
| 2 | Measurement of Intracellular Calcium | Physiological Reviews | 1999 | 665 |
| 3 | Association of BRCA1 with the hRad50-hMre11-p95 Complex and the DNA Damage Response | Science | 1999 | 583 |
| 4 | Function of Yeast Rad52 Protein as a Mediator between Replication Protein A and the Rad51 Recombinase | Journal of Biological Chemistry | 1997 | 489 |
| 5 | DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis | Oncogene | 1999 | 413 |
| 6 | Nuclease Activities in a Complex of Human Recombination and DNA Repair Factors Rad50, Mre11, and p95 | Journal of Biological Chemistry | 1998 | 346 |
| 7 | Yeast Mre11 and Rad1 Proteins Define a Ku-Independent Mechanism To Repair Double-Strand Breaks Lacking Overlapping End Sequences | Molecular and Cellular Biology | 2003 | 327 |
| 8 | Interleukin 6 secreted from adipose stromal cells promotes migration and invasion of breast cancer cells | Oncogene | 2009 | 267 |
| 9 | An interaction between DNA ligase I and proliferating cell nuclear antigen: Implications for Okazaki fragment synthesis and joining | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 232 |
| 10 | Temporal, spatial, and cell type–specific control of Cre-mediated DNA recombination in transgenic mice | Nature Biotechnology | 1999 | 221 |
| 11 | Interaction between PCNA and DNA ligase I is critical for joining of Okazaki fragments and long-patch base-excision repair | Current Biology | 2000 | 218 |
| 12 | Sequence-Specific Transcriptional Corepressor Function for BRCA1 through a Novel Zinc Finger Protein, ZBRK1 | Molecular Cell | 2000 | 218 |
| 13 | Physical and Functional Interaction between DNA Ligase IIIα and Poly(ADP-Ribose) Polymerase 1 in DNA Single-Strand Break Repair | Molecular and Cellular Biology | 2003 | 207 |
| 14 | Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks | EMBO Journal | 2010 | 197 |
| 15 | The Nuclear Localization Sequences of the BRCA1 Protein Interact with the Importin-α Subunit of the Nuclear Transport Signal Receptor | Journal of Biological Chemistry | 1996 | 182 |
| 16 | A New Member of the hsp90 Family of Molecular Chaperones Interacts with the Retinoblastoma Protein during Mitosis and after Heat Shock | Molecular and Cellular Biology | 1996 | 181 |
| 17 | DNA ligaseI is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factories | EMBO Journal | 1998 | 179 |
| 18 | Structure and function of mammalian DNA ligases | Mutation Research DNA Repair | 1998 | 179 |
| 19 | Microhomology-mediated end joining: Good, bad and ugly | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 2018 | 175 |
| 20 | Human meiotic recombinase Dmc1 promotes ATP-dependent homologous DNA strand exchange | Nature | 2004 | 174 |
| 21 | Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation | Nature Structural and Molecular Biology | 2011 | 165 |
| 22 | Lessons learned from BRCA1 and BRCA2 | Oncogene | 2000 | 158 |
| 23 | The checkpoint kinases Chk1 and Chk2 regulate the functional associations between hBRCA2 and Rad51 in response to DNA damage | Oncogene | 2008 | 147 |
| 24 | Multiple Interactions of Rad23 Suggest a Mechanism for Ubiquitylated Substrate Delivery Important in Proteolysis | Molecular Biology of the Cell | 2004 | 145 |
| 25 | HEC, a Novel Nuclear Protein Rich in Leucine Heptad Repeats Specifically Involved in Mitosis | Molecular and Cellular Biology | 1997 | 121 |
| 26 | BRCA1 Facilitates Microhomology-mediated End Joining of DNA Double Strand Breaks | Journal of Biological Chemistry | 2002 | 121 |
| 27 | Role of Dnl4–Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination | Nature Structural and Molecular Biology | 2007 | 118 |
| 28 | Phosphorylation of the Mitotic Regulator Protein Hec1 by Nek2 Kinase Is Essential for Faithful Chromosome Segregation | Journal of Biological Chemistry | 2002 | 117 |
| 29 | The Png1–Rad23 complex regulates glycoprotein turnover | Journal of Cell Biology | 2006 | 117 |
| 30 | An Alternative Splicing Event Which Occurs in Mouse Pachytene Spermatocytes Generates a Form of DNA Ligase III with Distinct Biochemical Properties That May Function in Meiotic Recombination | Molecular and Cellular Biology | 1997 | 115 |
| 31 | Proline- and Arginine-Rich Peptides Constitute a Novel Class of Allosteric Inhibitors of Proteasome Activity† | Biochemistry | 2003 | 112 |
| 32 | Mediator Modulates Gli3-Dependent Sonic Hedgehog Signaling | Molecular and Cellular Biology | 2006 | 112 |
| 33 | Mammalian DNA Ligase III: Molecular Cloning, Chromosomal Localization, and Expression in Spermatocytes Undergoing Meiotic Recombination | Molecular and Cellular Biology | 1995 | 109 |
| 34 | The role of the androgen receptor in the development of prostatic hyperplasia and prostate cancer | Molecular and Cellular Biochemistry | 2003 | 103 |
| 35 | Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Treatment | Endocrine Reviews | 2022 | 98 |
| 36 | AP180 and AP-2 Interact Directly in a Complex That Cooperatively Assembles Clathrin | Journal of Biological Chemistry | 1999 | 97 |
| 37 | Completion of base excision repair by mammalian DNA ligases | Progress in Molecular Biology and Translational Science | 2001 | 94 |
| 38 | Ubiquitin-mediated proteolysis of vertebrate G1- and S-phase regulators | Journal of Cellular Physiology | 2001 | 94 |
| 39 | Microhomology Directs Diverse DNA Break Repair Pathways and Chromosomal Translocations | PLoS Genetics | 2012 | 94 |
| 40 | A Role for the Clathrin Assembly Domain of AP180 in Synaptic Vesicle Endocytosis | Journal of Neuroscience | 1999 | 92 |
| 41 | DNA Ligase III Is Recruited to DNA Strand Breaks by a Zinc Finger Motif Homologous to That of Poly(ADP-ribose) Polymerase | Journal of Biological Chemistry | 1999 | 90 |
| 42 | Mediator kinase module and human tumorigenesis | Critical Reviews in Biochemistry and Molecular Biology | 2015 | 88 |
| 43 | Caretaker or undertaker? The role of the proteasome in aging | Mechanisms of Ageing and Development | 2001 | 84 |
| 44 | A Tetrahedral Transition State at the Active Sites of the 20S Proteasome Is Coupled to Opening of the α-Ring Channel | Structure | 2009 | 84 |
| 45 | Impact of Mitochondrial Ca 2+ Cycling on Pattern Formation and Stability | Biophysical Journal | 1999 | 78 |
| 46 | Mutations in MED12 Cause X-Linked Ohdo Syndrome | American Journal of Human Genetics | 2013 | 78 |
| 47 | Ionizing radiation-induced Rad51 nuclear focus formation is cell cycle-regulated and defective in both ATM−/− and c-Abl−/− cells | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 2003 | 77 |
| 48 | Mediator and human disease | Seminars in Cell and Developmental Biology | 2011 | 76 |
| 49 | Induction of DNA Replication-mediated Double Strand Breaks by Psoralen DNA Interstrand Cross-links | Journal of Biological Chemistry | 2003 | 73 |
| 50 | Mutations in Exon 1 Highlight the Role ofMED12in Uterine Leiomyomas | Human Mutation | 2014 | 67 |
