956(top 1%)
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69.2K(top 0.1%)
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131(top 0.1%)
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224(top 0.1%)
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997
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72.4K
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5.9K
citing journals

Top Articles

#TitleJournalYearCitations
1Guidelines for the use and interpretation of assays for monitoring autophagyAutophagy20123,122
2Extension of Murine Life Span by Overexpression of Catalase Targeted to MitochondriaScience20051,576
3Myotonic Dystrophy Type 2 Caused by a CCTG Expansion in Intron 1 of ZNF9Science20011,172
4Melatonin as a natural ally against oxidative stress: a physicochemical examinationJournal of Pineal Research2011963
5Trends in oxidative aging theoriesFree Radical Biology and Medicine2007897
6Melatonin in edible plants identified by radioimmunoassay and by high performance liquid chromatography-mass spectrometryJournal of Pineal Research1995884
7A review of the evidence supporting melatonin's role as an antioxidantJournal of Pineal Research1995775
8Melatonin: an ancient molecule that makes oxygen metabolically tolerableJournal of Pineal Research2015751
9On the free radical scavenging activities of melatonin's metabolites, AFMK and AMKJournal of Pineal Research2013679
10Measurement of Intracellular CalciumPhysiological Reviews1999665
11Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate agingPhysiological Genomics2003654
12Activation of innate immune antiviral responses by Nod2Nature Immunology2009643
13The chemistry of melatonin's interaction with reactive speciesJournal of Pineal Research2003630
14Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rateJournal of Pineal Research2008541
15Melatonin: A Multitasking MoleculeProgress in Brain Research2010520
16A review of the molecular aspects of melatonin’s anti‐inflammatory actions: recent insights and new perspectivesJournal of Pineal Research2013511
17Is the oxidative stress theory of aging dead?Biochimica Et Biophysica Acta - General Subjects2009502
18Chemical calcium indicatorsMethods2008460
19Effects of Melatonin Treatment in Septic NewbornsPediatric Research2001452
20Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitaminJournal of Pineal Research2003449
21Insulin resistance is a cellular antioxidant defense mechanismProceedings of the National Academy of Sciences of the United States of America2009449
22Number matters: control of mammalian mitochondrial DNA copy numberJournal of Genetics and Genomics2009440
23Melatonin, energy metabolism, and obesity: a reviewJournal of Pineal Research2014425
24Melatonin: Exceeding ExpectationsPhysiology2014401
25Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a reviewJournal of Pineal Research2014386
26Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosisJournal of Pineal Research2015384
27Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophyFree Radical Biology and Medicine2006378
28Postmeiotic Sex Chromatin in the Male Germline of MiceCurrent Biology2006370
29Melatonin and the ovary: physiological and pathophysiological implicationsFertility and Sterility2009363
30Melatonin, mitochondria, and cellular bioenergeticsJournal of Pineal Research2001350
31Distribution of melatonin in mammalian tissues: The relative importance of nuclear versus cytosolic localizationJournal of Pineal Research1993349
32Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and ParalysisJournal of Biological Chemistry2015347
33Methionine oxidation and agingBiochimica Et Biophysica Acta - Proteins and Proteomics2005343
34Free Radical‐Mediated Molecular DamageAnnals of the New York Academy of Sciences2001341
35The Safety of Melatonin in HumansClinical Drug Investigation2016320
36Maternally Inherited Aminoglycoside-Induced and Nonsyndromic Deafness Is Associated with the Novel C1494T Mutation in the Mitochondrial 12S rRNA Gene in a Large Chinese FamilyAmerican Journal of Human Genetics2004316
37Nuclear localization of melatonin in different mammalian tissues: Immunocytochemical and radioimmunoassay evidenceJournal of Cellular Biochemistry1993294
38The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivoCancer Letters1993290
39Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53.Genes and Development1994286
40Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS productionAmerican Journal of Physiology - Regulatory Integrative and Comparative Physiology2007285
41Role of redox-regulated transcription factors in inflammation, aging and age-related diseasesExperimental Gerontology2000275
42Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophagesJournal of Neuroimmunology2005274
43Melatonin prevents changes in microsomal membrane fluidity during induced lipid peroxidationFEBS Letters1997273
44Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulinJournal of Cellular Biochemistry1997263
45Mitochondria: Central Organelles for Melatonin′s Antioxidant and Anti-Aging ActionsMolecules2018263
46Melatonin: Current Status and Future Perspectives in Plant ScienceFrontiers in Plant Science2015262
47Oxidative stress of the newborn in the pre‐ and postnatal period and the clinical utility of melatoninJournal of Pineal Research2009261
48SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatoninAutophagy2015261
49Dynamics of Intracellular Movement and Nucleocytoplasmic Recycling of the Ligand-Activated Androgen Receptor in Living CellsMolecular Endocrinology2000258
50Significance and application of melatonin in the regulation of brown adipose tissue metabolism: relation to human obesityObesity Reviews2011257