| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Identification of plasmids by PCR-based replicon typing | Journal of Microbiological Methods | 2005 | 2,131 |
| 3 | Astrocytes are active players in cerebral innate immunity | Trends in Immunology | 2007 | 1,121 |
| 4 | High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients | PLoS ONE | 2009 | 806 |
| 5 | Cyclooxygenase-2 (COX-2) in Inflammatory and Degenerative Brain Diseases | Journal of Neuropathology and Experimental Neurology | 2004 | 636 |
| 6 | Ultrasonic vocalizations: A tool for behavioural phenotyping of mouse models of neurodevelopmental disorders | Neuroscience and Biobehavioral Reviews | 2009 | 413 |
| 7 | Genetic prion disease: the EUROCJD experience | Human Genetics | 2005 | 391 |
| 8 | Dark microglia: A new phenotype predominantly associated with pathological states | Glia | 2016 | 325 |
| 9 | Unusual repertoire of vocalizations in adult BTBR T+tf/J mice during three types of social encounters | Genes, Brain and Behavior | 2011 | 316 |
| 10 | Cyclophosphamide Synergizes with Type I Interferons through Systemic Dendritic Cell Reactivation and Induction of Immunogenic Tumor Apoptosis | Cancer Research | 2011 | 304 |
| 11 | Role of inflammation in neurodegenerative diseases | Current Opinion in Neurology | 2005 | 300 |
| 12 | Quantifying prion disease penetrance using large population control cohorts | Science Translational Medicine | 2016 | 289 |
| 13 | Immunomodulatory effects of cyclophosphamide and implementations for vaccine design | Seminars in Immunopathology | 2011 | 265 |
| 14 | Alterations of Choline Phospholipid Metabolism in Ovarian Tumor Progression | Cancer Research | 2005 | 258 |
| 15 | Triple‐negative breast cancer: Present challenges and new perspectives | Molecular Oncology | 2010 | 252 |
| 16 | Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies | Brain | 2004 | 244 |
| 17 | Interferon-α and cancer: Mechanisms of action and new perspectives of clinical use | Biochimie | 2007 | 243 |
| 18 | pH‐dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity | International Journal of Cancer | 2010 | 237 |
| 19 | Cyclophosphamide Enhances the Antitumor Efficacy of Adoptively Transferred Immune Cells through the Induction of Cytokine Expression, B-Cell and T-Cell Homeostatic Proliferation, and Specific Tumor Infiltration | Clinical Cancer Research | 2007 | 228 |
| 20 | Incidence and spectrum of sporadic Creutzfeldt–Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification | Acta Neuropathologica | 2009 | 224 |
| 21 | Internet Addiction in adolescence: Neurobiological, psychosocial and clinical issues | Neuroscience and Biobehavioral Reviews | 2017 | 218 |
| 22 | Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures | Journal of Neuroinflammation | 2005 | 209 |
| 23 | Reciprocal Activating Interaction Between Dendritic Cells and Pamidronate-Stimulated γδ T Cells: Role of CD86 and Inflammatory Cytokines | Journal of Immunology | 2005 | 208 |
| 24 | Efficient Transmission and Characterization of Creutzfeldt–Jakob Disease Strains in Bank Voles | PLoS Pathogens | 2006 | 201 |
| 25 | Activation of Phosphatidylcholine Cycle Enzymes in Human Epithelial Ovarian Cancer Cells | Cancer Research | 2010 | 196 |
| 26 | European Society for Paediatric Endocrinology Consensus Guidelines on Screening, Diagnosis, and Management of Congenital Hypothyroidism | Hormone Research in Paediatrics | 2014 | 193 |
| 27 | Fractalkine receptor deficiency impairs microglial and neuronal responsiveness to chronic stress | Brain, Behavior, and Immunity | 2016 | 192 |
| 28 | PPAR-γ Agonists as Regulators of Microglial Activation and Brain Inflammation | Current Pharmaceutical Design | 2006 | 191 |
| 29 | B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-β deposition in mice | Molecular and Cellular Neurosciences | 2008 | 183 |
| 30 | Inhibition of Smad7 With a Specific Antisense Oligonucleotide Facilitates TGF-β1–Mediated Suppression of Colitis | Gastroenterology | 2006 | 182 |
| 31 | Chronic and Acute Intranasal Oxytocin Produce Divergent Social Effects in Mice | Neuropsychopharmacology | 2014 | 176 |
| 32 | Diagnosis of Human Prion Disease Using Real-Time Quaking-Induced Conversion Testing of Olfactory Mucosa and Cerebrospinal Fluid Samples | JAMA Neurology | 2017 | 176 |
| 33 | Circulating miRNAs as Biomarkers for Neurodegenerative Disorders | Molecules | 2014 | 167 |
| 34 | Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation | Brain Research Reviews | 2005 | 158 |
| 35 | Developmental Neurotoxicity of Organophosphorous Pesticides: Fetal and Neonatal Exposure to Chlorpyrifos Alters Sex-Specific Behaviors at Adulthood in Mice | Toxicological Sciences | 2006 | 158 |
| 36 | Estrogen receptor profiles in human peripheral blood lymphocytes | Immunology Letters | 2010 | 157 |
| 37 | Doxycycline in Creutzfeldt-Jakob disease: a phase 2, randomised, double-blind, placebo-controlled trial | Lancet Neurology, The | 2014 | 157 |
| 38 | Fluoxetine effects on molecular, cellular and behavioral endophenotypes of depression are driven by the living environment | Molecular Psychiatry | 2017 | 150 |
| 39 | Astrocytes Produce Dendritic Cell-Attracting Chemokines In Vitro and in Multiple Sclerosis Lesions | Journal of Neuropathology and Experimental Neurology | 2005 | 149 |
| 40 | Intrahippocampal administration of BDNF in adult rats affects short-term behavioral plasticity in the Morris water maze and performance in the elevated plus-maze | Hippocampus | 2004 | 144 |
| 41 | Enriched environment and acceleration of visual system development | Neuropharmacology | 2004 | 144 |
| 42 | Suppressive Effect of 1α,25-Dihydroxyvitamin D3 on Type I IFN-Mediated Monocyte Differentiation into Dendritic Cells: Impairment of Functional Activities and Chemotaxis | Journal of Immunology | 2005 | 140 |
| 43 | Exosomes from Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Cells License Quiescent CD4 + T Lymphocytes To Replicate HIV-1 through a Nef- and ADAM17-Dependent Mechanism | Journal of Virology | 2014 | 140 |
| 44 | Mineralocorticoid receptor antagonism induces browning of white adipose tissue through impairment of autophagy and prevents adipocyte dysfunction in high‐fat‐diet‐fed mice | FASEB Journal | 2014 | 139 |
| 45 | T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy | FASEB Journal | 2012 | 138 |
| 46 | Role of autophagy in immunity and autoimmunity, with a special focus on systemic lupus erythematosus | FASEB Journal | 2012 | 137 |
| 47 | Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt–Jakob disease and rapid dementias: a longitudinal multicentre study over 10 years | Brain | 2012 | 135 |
| 48 | Microglia-Neuron Interaction in Inflammatory and Degenerative Diseases: Role of Cholinergic and Noradrenergic Systems | CNS and Neurological Disorders - Drug Targets | 2007 | 133 |
| 49 | IFN-α-conditioned dendritic cells are highly efficient in inducing cross-priming CD8+ T cells against exogenous viral antigens | European Journal of Immunology | 2006 | 132 |
| 50 | Metabotropic P2 receptor activation regulates oligodendrocyte progenitor migration and development | Glia | 2005 | 129 |
