| # | Title | Journal | Year | Citations |
|---|
| 1 | Proposals for the Classification of the Acute Leukaemias French‐American‐British (FAB) Co‐operative Group | British Journal of Haematology | 1976 | 5,316 |
| 2 | Improved Survival with an Implanted Defibrillator in Patients with Coronary Disease at High Risk for Ventricular Arrhythmia | New England Journal of Medicine | 1996 | 3,859 |
| 3 | Staining of Tissue Sections for Electron Microscopy with Heavy Metals | Journal of Cell Biology | 1958 | 3,825 |
| 4 | Core outcome measures for chronic pain clinical trials: IMMPACT recommendations | Pain | 2005 | 2,915 |
| 5 | Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis | Lancet Neurology, The | 2015 | 2,776 |
| 6 | PERSPECTIVE ARTICLE: Growth factors and cytokines in wound healing | Wound Repair and Regeneration | 2008 | 2,771 |
| 7 | Interpreting the Clinical Importance of Treatment Outcomes in Chronic Pain Clinical Trials: IMMPACT Recommendations | Journal of Pain | 2008 | 2,564 |
| 8 | Neonatal Outcomes of Extremely Preterm Infants From the NICHD Neonatal Research Network | Pediatrics | 2010 | 2,252 |
| 9 | Proposals for the classification of the myelodysplastic syndromes | British Journal of Haematology | 1982 | 2,230 |
| 10 | Defining and Assessing Professional Competence | JAMA - Journal of the American Medical Association | 2002 | 2,119 |
| 11 | Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012 | JAMA - Journal of the American Medical Association | 2015 | 2,008 |
| 12 | Prevalence of a Metabolic Syndrome Phenotype in Adolescents | JAMA Pediatrics | 2003 | 1,876 |
| 13 | The Burden of Respiratory Syncytial Virus Infection in Young Children | New England Journal of Medicine | 2009 | 1,797 |
| 14 | Bone Morphogenetic Proteins | Growth Factors | 2004 | 1,787 |
| 15 | American Society of Clinical Oncology Guideline Recommendations for Sentinel Lymph Node Biopsy in Early-Stage Breast Cancer | Journal of Clinical Oncology | 2005 | 1,674 |
| 16 | Cell and environment interactions in tumor microregions: the multicell spheroid model | Science | 1988 | 1,652 |
| 17 | How does communication heal? Pathways linking clinician–patient communication to health outcomes | Patient Education and Counseling | 2009 | 1,640 |
| 18 | Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease | New England Journal of Medicine | 2014 | 1,613 |
| 19 | Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus | Nature Immunology | 2000 | 1,482 |
| 20 | miR-145 and miR-143 regulate smooth muscle cell fate and plasticity | Nature | 2009 | 1,412 |
| 21 | Methylmercury Poisoning in Iraq | Science | 1973 | 1,405 |
| 22 | Fall risk index for elderly patients based on number of chronic disabilities | American Journal of Medicine | 1986 | 1,391 |
| 23 | Assessment in Medical Education | New England Journal of Medicine | 2007 | 1,368 |
| 24 | Neuropathic pain | Nature Reviews Disease Primers | 2017 | 1,360 |
| 25 | Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 1,332 |
| 26 | Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study | Lancet, The | 2009 | 1,327 |
| 27 | Neuroinflammation and M2 microglia: the good, the bad, and the inflamed | Journal of Neuroinflammation | 2014 | 1,285 |
| 28 | Sperm Morphology, Motility, and Concentration in Fertile and Infertile Men | New England Journal of Medicine | 2001 | 1,133 |
| 29 | lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3′ UTRs via Alu elements | Nature | 2011 | 1,122 |
| 30 | DNA sequence required for efficient transcription termination in yeast | Cell | 1982 | 1,093 |
| 31 | Recommendations for the Pharmacological Management of Neuropathic Pain: An Overview and Literature Update | Mayo Clinic Proceedings | 2010 | 1,083 |
| 32 | Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics | Nature Reviews Molecular Cell Biology | 2004 | 1,070 |
| 33 | Prostaglandins as modulators of immunity | Trends in Immunology | 2002 | 1,047 |
| 34 | Respiratory Syncytial Virus and Parainfluenza Virus | New England Journal of Medicine | 2001 | 1,041 |
| 35 | The Prevalence of Chronic Pain in United States Adults: Results of an Internet-Based Survey | Journal of Pain | 2010 | 1,038 |
| 36 | Chromatographic separation, identification, and analysis of phosphatides | Journal of Lipid Research | 1962 | 1,025 |
| 37 | Omega-3 Fatty Acids EPA and DHA: Health Benefits Throughout Life | Advances in Nutrition | 2012 | 1,024 |
| 38 | Glial regulation of the cerebral microvasculature | Nature Neuroscience | 2007 | 1,003 |
| 39 | Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 988 |
| 40 | Bacterial Quorum Sensing in Pathogenic Relationships | Infection and Immunity | 2000 | 976 |
| 41 | Characterization of a rare IL-10–competent B-cell subset in humans that parallels mouse regulatory B10 cells | Blood | 2011 | 969 |
| 42 | Mindful Practice | JAMA - Journal of the American Medical Association | 1999 | 954 |
| 43 | Mitochondrial membrane potential probes and the proton gradient: a practical usage guide | BioTechniques | 2011 | 924 |
| 44 | Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes | Journal of Bacteriology | 1997 | 912 |
| 45 | The long QT syndrome. Prospective longitudinal study of 328 families. | Circulation | 1991 | 905 |
| 46 | Interaction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant Axons | Journal of General Physiology | 1971 | 886 |
| 47 | Influenza | Nature Reviews Disease Primers | 2018 | 880 |
| 48 | Microarray Analysis of Pseudomonas aeruginosa Quorum-Sensing Regulons: Effects of Growth Phase and Environment | Journal of Bacteriology | 2003 | 854 |
| 49 | Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication | Science | 1993 | 846 |
| 50 | Gender Differences in Caregiver Stressors, Social Resources, and Health: An Updated Meta-Analysis | Journals of Gerontology - Series B Psychological Sciences and Social Sciences | 2006 | 844 |
