| # | Title | Journal | Year | Citations |
|---|
| 1 | Neutrophils and immunity: challenges and opportunities | Nature Reviews Immunology | 2006 | 2,394 |
| 2 | Points of control in inflammation | Nature | 2002 | 2,262 |
| 3 | Nonresolving Inflammation | Cell | 2010 | 1,717 |
| 4 | Beyond oxidative stress: an immunologist's guide to reactive oxygen species | Nature Reviews Immunology | 2013 | 1,181 |
| 5 | The spectrum of latent tuberculosis: rethinking the biology and intervention strategies | Nature Reviews Microbiology | 2009 | 1,179 |
| 6 | Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis | Nature | 2006 | 1,113 |
| 7 | A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies | PLoS Pathogens | 2013 | 835 |
| 8 | Plasma membrane phosphoinositide organization by protein electrostatics | Nature | 2005 | 788 |
| 9 | Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity | Nature | 2015 | 788 |
| 10 | PIP2and Proteins: Interactions, Organization, and Information Flow | Annual Review of Biophysics and Biomolecular Structure | 2002 | 771 |
| 11 | HIV vaccine design and the neutralizing antibody problem | Nature Immunology | 2004 | 721 |
| 12 | The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice | Science | 2011 | 644 |
| 13 | Peroxynitrite reductase activity of bacterial peroxiredoxins | Nature | 2000 | 629 |
| 14 | Conversion of Proepithelin to Epithelins | Cell | 2002 | 584 |
| 15 | dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway | Science | 2012 | 558 |
| 16 | The Mannose-Dependent Epitope for Neutralizing Antibody 2G12 on Human Immunodeficiency Virus Type 1 Glycoprotein gp120 | Journal of Virology | 2002 | 528 |
| 17 | Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis | MBio | 2017 | 496 |
| 18 | The Proteasome of Mycobacterium tuberculosis Is Required for Resistance to Nitric Oxide | Science | 2003 | 489 |
| 19 | Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway | PLoS Genetics | 2012 | 489 |
| 20 | HIV-1 neutralizing antibodies induced by native-like envelope trimers | Science | 2015 | 482 |
| 21 | Phenotype of Mice and Macrophages Deficient in Both Phagocyte Oxidase and Inducible Nitric Oxide Synthase | Immunity | 1999 | 472 |
| 22 | Inhibiting sexual transmission of HIV-1 infection | Nature Reviews Microbiology | 2003 | 468 |
| 23 | The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation | Nature | 2017 | 460 |
| 24 | Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120 | Nature Medicine | 2003 | 453 |
| 25 | The CCR5 and CXCR4 Coreceptors—Central to Understanding the Transmission and Pathogenesis of Human Immunodeficiency Virus Type 1 Infection | AIDS Research and Human Retroviruses | 2004 | 441 |
| 26 | Reprogramming of the Macrophage Transcriptome in Response to Interferon-γ and Mycobacterium tuberculosis | Journal of Experimental Medicine | 2001 | 437 |
| 27 | Emerging Functions of Amphiregulin in Orchestrating Immunity, Inflammation, and Tissue Repair | Immunity | 2015 | 429 |
| 28 | The Structure and Function of Telomerase Reverse Transcriptase | Annual Review of Biochemistry | 2006 | 427 |
| 29 | Stabilization of the Soluble, Cleaved, Trimeric Form of the Envelope Glycoprotein Complex of Human Immunodeficiency Virus Type 1 | Journal of Virology | 2002 | 424 |
| 30 | Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria–specific CD4 + T cells | Science | 2015 | 421 |
| 31 | Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice | Journal of Experimental Medicine | 2010 | 411 |
| 32 | IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin–EGFR interactions | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 407 |
| 33 | Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface | Nature | 2014 | 400 |
| 34 | Immune Regulation of Metabolic Homeostasis in Health and Disease | Cell | 2015 | 380 |
| 35 | Metabolic Enzymes of Mycobacteria Linked to Antioxidant Defense by a Thioredoxin-Like Protein | Science | 2002 | 378 |
| 36 | Mycobacterial survival strategies in the phagosome: defence against host stresses | Cellular Microbiology | 2009 | 377 |
| 37 | Antibiotic Resistance — Problems, Progress, and Prospects | New England Journal of Medicine | 2014 | 377 |
| 38 | Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform | Nature Microbiology | 2017 | 368 |
| 39 | Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes | Cell | 2015 | 341 |
| 40 | Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor | Nucleic Acids Research | 2005 | 334 |
| 41 | Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 324 |
| 42 | Genome-Wide Analysis of Membrane Targeting by S. cerevisiae Pleckstrin Homology Domains | Molecular Cell | 2004 | 315 |
| 43 | Metabolomics of Mycobacterium tuberculosis Reveals Compartmentalized Co-Catabolism of Carbon Substrates | Chemistry and Biology | 2010 | 313 |
| 44 | Peptide Methionine Sulfoxide Reductase: Structure, Mechanism of Action, and Biological Function | Archives of Biochemistry and Biophysics | 2002 | 302 |
| 45 | Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus–cell fusion | Nature | 2005 | 302 |
| 46 | Expression switching in thestevorandPfmc-2TMsuperfamilies inPlasmodium falciparum | Molecular Microbiology | 2007 | 291 |
| 47 | Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 286 |
| 48 | Electrostatic Sequestration of PIP2 on Phospholipid Membranes by Basic/Aromatic Regions of Proteins | Biophysical Journal | 2004 | 285 |
| 49 | Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis | Nature Chemical Biology | 2005 | 279 |
| 50 | Common strategies for antigenic variation by bacterial, fungal and protozoan pathogens | Nature Reviews Microbiology | 2009 | 277 |
