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1A new method of classifying prognostic comorbidity in longitudinal studies: Development and validationJournal of Chronic Diseases198740,131
2The 2016 revision of the World Health Organization classification of lymphoid neoplasmsBlood20165,965
3Nitric oxide as a secretory product of mammalian cellsFASEB Journal19924,161
4NITRIC OXIDE AND MACROPHAGE FUNCTIONAnnual Review of Immunology19973,707
5Nitric oxide synthases: Roles, tolls, and controlsCell19942,815
6International evidence-based recommendations for point-of-care lung ultrasoundIntensive Care Medicine20122,641
7Efficacy of Gefitinib, an Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase, in Symptomatic Patients With Non–Small Cell Lung CancerJAMA - Journal of the American Medical Association20032,360
9Analysis of Tumor Specimens at the Time of Acquired Resistance to EGFR-TKI Therapy in 155 Patients with EGFR-Mutant Lung CancersClinical Cancer Research20132,097
10Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liverNature Cell Biology20152,064
11Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic FactorCell20132,013
12Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapyNature Medicine19991,962
13Cloning and characterization of inducible nitric oxide synthase from mouse macrophagesScience19921,879
14Production of large amounts of hydrogen peroxide by human tumor cellsCancer Research19911,841
15Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencingNature Biotechnology20131,785
16Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells.Journal of Experimental Medicine19891,700
17Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell CarcinomaJournal of Clinical Oncology19991,641
18Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthaseJournal of Biological Chemistry19941,626
19MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinibProceedings of the National Academy of Sciences of the United States of America20071,557
20methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profilesGenome Biology20121,541
21Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistanceNature20151,498
22Regulation of Cell Survival by Secreted ProneurotrophinsScience20011,482
23Role of nitric oxide synthesis in macrophage antimicrobial activityCurrent Opinion in Immunology19911,462
24Advances in leishmaniasisLancet, The20051,451
25Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1Autophagy20211,430
26Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthaseCell19951,424
27Double-stranded DNA in exosomes: a novel biomarker in cancer detectionCell Research20141,282
28Steroid 5α-Reductase Deficiency in Man: An Inherited Form of Male PseudohermaphroditismScience19741,232
29Genetic Variant BDNF (Val66Met) Polymorphism Alters Anxiety-Related BehaviorScience20061,201
30Macrophage deactivation by interleukin 10.Journal of Experimental Medicine19911,181
31High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptorNature19911,172
32Regulation of biosynthesis of nitric oxideJournal of Biological Chemistry19941,157
33Brca1 Controls Homology-Directed DNA RepairMolecular Cell19991,135
34Punctuated Evolution of Prostate Cancer GenomesCell20131,107
35Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide.Journal of Experimental Medicine19931,103
36Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cellsNature Biotechnology20101,080
37Cleavage of proBDNF by tPA/Plasmin Is Essential for Long-Term Hippocampal PlasticityScience20041,014
38Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial functionNature2014998
39CD36: a class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolismJournal of Clinical Investigation2001948
40Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1Nature Medicine2000931
41Deactivation of macrophages by transforming growth factor-βNature1988862
42Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in miceJournal of Clinical Investigation2000861
43Inducible nitric oxide synthase: what difference does it make?Journal of Clinical Investigation1997860
44ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75NTRand SortilinJournal of Neuroscience2005857
45Pancreatic stellate cells support tumour metabolism through autophagic alanine secretionNature2016843
46Genomic correlates of clinical outcome in advanced prostate cancerProceedings of the National Academy of Sciences of the United States of America2019839
47Testicular Germ-Cell CancerNew England Journal of Medicine1997832
48Acute Promyelocytic LeukemiaNew England Journal of Medicine1993822
49G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activatorNature1998821
50Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regenerationNature2015818