# | Title | Journal | Year | Citations |
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1 | A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation | Journal of Chronic Diseases | 1987 | 40,131 |
2 | The 2016 revision of the World Health Organization classification of lymphoid neoplasms | Blood | 2016 | 5,965 |
3 | Nitric oxide as a secretory product of mammalian cells | FASEB Journal | 1992 | 4,161 |
4 | NITRIC OXIDE AND MACROPHAGE FUNCTION | Annual Review of Immunology | 1997 | 3,707 |
5 | Nitric oxide synthases: Roles, tolls, and controls | Cell | 1994 | 2,815 |
6 | International evidence-based recommendations for point-of-care lung ultrasound | Intensive Care Medicine | 2012 | 2,641 |
7 | Efficacy of Gefitinib, an Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase, in Symptomatic Patients With Non–Small Cell Lung Cancer | JAMA - Journal of the American Medical Association | 2003 | 2,360 |
8 | A MICROCOLORIMETRIC METHOD FOR THE DETERMINATION OF INORGANIC PHOSPHORUS | Journal of Biological Chemistry | 1953 | 2,289 |
9 | Analysis of Tumor Specimens at the Time of Acquired Resistance to EGFR-TKI Therapy in 155 Patients with EGFR-Mutant Lung Cancers | Clinical Cancer Research | 2013 | 2,097 |
10 | Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver | Nature Cell Biology | 2015 | 2,064 |
11 | Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor | Cell | 2013 | 2,013 |
12 | Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy | Nature Medicine | 1999 | 1,962 |
13 | Cloning and characterization of inducible nitric oxide synthase from mouse macrophages | Science | 1992 | 1,879 |
14 | Production of large amounts of hydrogen peroxide by human tumor cells | Cancer Research | 1991 | 1,841 |
15 | Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing | Nature Biotechnology | 2013 | 1,785 |
16 | Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. | Journal of Experimental Medicine | 1989 | 1,700 |
17 | Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma | Journal of Clinical Oncology | 1999 | 1,641 |
18 | Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase | Journal of Biological Chemistry | 1994 | 1,626 |
19 | MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 1,557 |
20 | methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles | Genome Biology | 2012 | 1,541 |
21 | Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance | Nature | 2015 | 1,498 |
22 | Regulation of Cell Survival by Secreted Proneurotrophins | Science | 2001 | 1,482 |
23 | Role of nitric oxide synthesis in macrophage antimicrobial activity | Current Opinion in Immunology | 1991 | 1,462 |
24 | Advances in leishmaniasis | Lancet, The | 2005 | 1,451 |
25 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
26 | Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase | Cell | 1995 | 1,424 |
27 | Double-stranded DNA in exosomes: a novel biomarker in cancer detection | Cell Research | 2014 | 1,282 |
28 | Steroid 5agr-Reductase Deficiency in Man: An Inherited Form of Male Pseudohermaphroditism | Science | 1974 | 1,232 |
29 | Genetic Variant BDNF (Val66Met) Polymorphism Alters Anxiety-Related Behavior | Science | 2006 | 1,201 |
30 | Macrophage deactivation by interleukin 10. | Journal of Experimental Medicine | 1991 | 1,181 |
31 | High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor | Nature | 1991 | 1,172 |
32 | Regulation of biosynthesis of nitric oxide | Journal of Biological Chemistry | 1994 | 1,157 |
33 | Brca1 Controls Homology-Directed DNA Repair | Molecular Cell | 1999 | 1,135 |
34 | Punctuated Evolution of Prostate Cancer Genomes | Cell | 2013 | 1,107 |
35 | Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide. | Journal of Experimental Medicine | 1993 | 1,103 |
36 | Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells | Nature Biotechnology | 2010 | 1,080 |
37 | Cleavage of proBDNF by tPA/Plasmin Is Essential for Long-Term Hippocampal Plasticity | Science | 2004 | 1,014 |
38 | Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function | Nature | 2014 | 998 |
39 | CD36: a class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolism | Journal of Clinical Investigation | 2001 | 948 |
40 | Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1 | Nature Medicine | 2000 | 931 |
41 | Deactivation of macrophages by transforming growth factor-β | Nature | 1988 | 862 |
42 | Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice | Journal of Clinical Investigation | 2000 | 861 |
43 | Inducible nitric oxide synthase: what difference does it make? | Journal of Clinical Investigation | 1997 | 860 |
44 | ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75NTR and Sortilin | Journal of Neuroscience | 2005 | 857 |
45 | Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion | Nature | 2016 | 843 |
46 | Genomic correlates of clinical outcome in advanced prostate cancer | Proceedings of the National Academy of Sciences of the United States of America | 2019 | 839 |
47 | Testicular Germ-Cell Cancer | New England Journal of Medicine | 1997 | 832 |
48 | Acute Promyelocytic Leukemia | New England Journal of Medicine | 1993 | 822 |
49 | G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator | Nature | 1998 | 821 |
50 | Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration | Nature | 2015 | 818 |