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Top Articles

#TitleJournalYearCitations
1HBx-upregulated lncRNA UCA1 promotes cell growth and tumorigenesis by recruiting EZH2 and repressing p27Kip1/CDK2 signalingScientific Reports2016126
2HBx-mediated miR-21 upregulation represses tumor-suppressor function of PDCD4 in hepatocellular carcinomaOncogene2013103
3LncRNA UCA1 promotes tumor metastasis by inducing miR-203/ZEB2 axis in gastric cancerCell Death and Disease201873
4Deregulation between miR-29b/c and DNMT3A Is Associated with Epigenetic Silencing of the CDH1 Gene, Affecting Cell Migration and Invasion in Gastric CancerPLoS ONE201565
5DNA methyltransferase 3A isoform b contributes to repressing E-cadherin through cooperation of DNA methylation and H3K27/H3K9 methylation in EMT-related metastasis of gastric cancerOncogene201856
6LncRNA TRERNA1 Function as an Enhancer of SNAI1 Promotes Gastric Cancer Metastasis by Regulating Epithelial-Mesenchymal TransitionMolecular Therapy - Nucleic Acids201749
7TRERNA1 upregulation mediated by HBx promotes sorafenib resistance and cell proliferation in HCC via targeting NRAS by sponging miR-22-3pMolecular Therapy202138
8Downregulated PITX1 Modulated by MiR-19a-3p Promotes Cell Malignancy and Predicts a Poor Prognosis of Gastric Cancer by Affecting Transcriptionally Activated PDCD5Cellular Physiology and Biochemistry201831
9Upregulation of DNMT1 mediated by HBx suppresses RASSF1A expression independent of DNA methylationOncology Reports201429
10H3K9me3, H3K36me3, and H4K20me3 Expression Correlates with Patient Outcome in Esophageal Squamous Cell Carcinoma as Epigenetic MarkersDigestive Diseases and Sciences201928
11DNA methyltransferase 3A promotes cell proliferation by silencing CDK inhibitor p18INK4C in gastric carcinogenesisScientific Reports201526
12HBx represses RIZ1 expression by DNA methyltransferase 1 involvement in decreased miR-152 in hepatocellular carcinomaOncology Reports201725
13LncRNA TRERNA1 facilitates hepatocellular carcinoma metastasis by dimethylating H3K9 in the CDH1 promoter region via the recruitment of the EHMT2/SNAI1 complexCell Proliferation201921
14Elevated TFAP4 regulates lncRNA TRERNA1 to promote cell migration and invasion in gastric cancerOncology Reports201818
15HBx increases chromatin accessibility and ETV4 expression to regulate dishevelled-2 and promote HCC progressionCell Death and Disease202216
16Methylation Patterns of Lys9 and Lys27 on Histone H3 Correlate with Patient Outcome in Gastric CancerDigestive Diseases and Sciences201913
17Targeting complexes of super‑enhancers is a promising strategy for cancer therapy (Review)Oncology Letters202012
18High methylation levels of histone H3 lysine 9 associated with activation of hypoxia-inducible factor 1α (HIF-1α) predict patients’ worse prognosis in human hepatocellular carcinomasCancer Genetics202011
19Alterations of plasma exosomal proteins and motabolies are associated with the progression of castration-resistant prostate cancerJournal of Translational Medicine20239
20Upregulation of LINC00659 expression predicts a poor prognosis and promotes migration and invasion of gastric cancer cellsOncology Letters20218
21Elevated LncRNA TRERNA1 correlated with activation of HIF-1α predicts poor prognosis in hepatocellular carcinomaPathology Research and Practice20216
22Expression and functions of transient receptor potential channels in liver diseasesActa Pharmaceutica Sinica B20235
23H3K27 trimethylation and H3K9 dimethylation as poor prognostic markers for patients with esophageal squamous cell carcinomaInternational Journal of Clinical and Experimental Pathology20194
24Silenced PITX1 promotes chemotherapeutic resistance to 5‑fluorocytosine and cisplatin in gastric cancer cellsExperimental and Therapeutic Medicine20193
25H3K27me3 Inactivates SFRP1 to Promote Cell Proliferation via Wnt/β-Catenin Signaling Pathway in Esophageal Squamous Cell CarcinomaDigestive Diseases and Sciences20232
26Hypoxia-inducible factor-1α cooperates with histone Lys methylation to predict prognosis in esophageal squamous cell carcinomaBiomarkers in Medicine20211
27[Corrigendum] Upregulation of LINC00659 expression predicts a poor prognosis and promotes migration and invasion of gastric cancer cellsOncology Letters20230