| # | Title | Journal | Year | Citations |
|---|
| 1 | DPP-4 inhibitors: pharmacological differences and their clinical implications | Expert Opinion on Drug Safety | 2014 | 588 |
| 2 | Cancer stem cells in solid tumors: an overview and new approaches for their isolation and characterization | FASEB Journal | 2013 | 338 |
| 3 | Exercise Modifies the Gut Microbiota with Positive Health Effects | Oxidative Medicine and Cellular Longevity | 2017 | 326 |
| 4 | Elevation of Endocannabinoid Levels in the Ventrolateral Periaqueductal Grey through Inhibition of Fatty Acid Amide Hydrolase Affects Descending Nociceptive Pathways via Both Cannabinoid Receptor Type 1 and Transient Receptor Potential Vanilloid Type-1 Receptors | Journal of Pharmacology and Experimental Therapeutics | 2006 | 260 |
| 5 | Acute Hyperglycemia Induces Nitrotyrosine Formation and Apoptosis in Perfused Heart From Rat | Diabetes | 2002 | 256 |
| 6 | Oxidative Stress and Cellular Response to Doxorubicin: A Common Factor in the Complex Milieu of Anthracycline Cardiotoxicity | Oxidative Medicine and Cellular Longevity | 2017 | 255 |
| 7 | Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice | Brain, Behavior, and Immunity | 2018 | 246 |
| 8 | Chemotherapeutic Drugs and Mitochondrial Dysfunction: Focus on Doxorubicin, Trastuzumab, and Sunitinib | Oxidative Medicine and Cellular Longevity | 2018 | 237 |
| 9 | Trehalose production: exploiting novel approaches | Trends in Biotechnology | 2002 | 224 |
| 10 | Cell cycle regulation and neural differentiation | Oncogene | 2003 | 222 |
| 11 | β2-Agonist Therapy in Lung Disease | American Journal of Respiratory and Critical Care Medicine | 2013 | 221 |
| 12 | Improvement of survival in Duchenne Muscular Dystrophy: retrospective analysis of 835 patients | Acta Myologica | 2012 | 221 |
| 13 | A Systematic Review With Meta-Analysis of Dual Bronchodilation With LAMA/LABA for the Treatment of Stable COPD | Chest | 2016 | 206 |
| 14 | Public Knowledge, Attitudes, and Experience Regarding the Use of Antibiotics in Italy | PLoS ONE | 2013 | 205 |
| 15 | Human primary bone sarcomas contain CD133+cancer stem cells displaying high tumorigenicityin vivo | FASEB Journal | 2011 | 190 |
| 16 | Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 181 |
| 17 | Analgesic actions of N -arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors | British Journal of Pharmacology | 2007 | 178 |
| 18 | Dental pulp stem cells: State of the art and suggestions for a true translation of research into therapy | Journal of Dentistry | 2014 | 155 |
| 19 | Investigating Italian parents' vaccine hesitancy: A cross-sectional survey | Human Vaccines and Immunotherapeutics | 2018 | 154 |
| 20 | Myocardial infarction in diabetic rats: role of hyperglycaemia on infarct size and early expression of hypoxia-inducible factor 1 | Diabetologia | 2002 | 153 |
| 21 | Epithelial to Mesenchymal Transition by TGFβ-1 Induction Increases Stemness Characteristics in Primary Non Small Cell Lung Cancer Cell Line | PLoS ONE | 2011 | 153 |
| 22 | Colorectal cancer association with metabolic syndrome and its components: a systematic review with meta-analysis | Endocrine | 2013 | 152 |
| 23 | Circulating microRNA changes in heart failure patients treated with cardiac resynchronization therapy: responders vs. non‐responders | European Journal of Heart Failure | 2013 | 143 |
| 24 | Severe respiratory SARS-CoV2 infection: Does ACE2 receptor matter? | Respiratory Medicine | 2020 | 143 |
| 25 | β2‐adrenoceptor agonists: current and future direction | British Journal of Pharmacology | 2011 | 142 |
| 26 | Industrial Systems Biology of Saccharomyces cerevisiae Enables Novel Succinic Acid Cell Factory | PLoS ONE | 2013 | 142 |
| 27 | Neuro-toxic and Reproductive Effects of BPA | Current Neuropharmacology | 2019 | 141 |
| 28 | Long-term inhibition of dipeptidyl peptidase-4 in Alzheimer’s prone mice | Experimental Gerontology | 2010 | 138 |
| 29 | A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo | Cell Death and Disease | 2018 | 138 |
| 30 | The effect of N -acetylcysteine on biofilms: Implications for the treatment of respiratory tract infections | Respiratory Medicine | 2016 | 136 |
| 31 | Curcumin, Gut Microbiota, and Neuroprotection | Nutrients | 2019 | 134 |
| 32 | The endovanilloid/endocannabinoid system in human osteoclasts: Possible involvement in bone formation and resorption | Bone | 2009 | 132 |
| 33 | Enzymatic determination of BPA by means of tyrosinase immobilized on different carbon carriers | Biosensors and Bioelectronics | 2007 | 131 |
| 34 | Optimizing drug delivery in COPD: The role of inhaler devices | Respiratory Medicine | 2017 | 131 |
| 35 | Microbial Diseases of Bivalve Mollusks: Infections, Immunology and Antimicrobial Defense | Marine Drugs | 2017 | 127 |
| 36 | The pharmacodynamic effects of single inhaled doses of formoterol, tiotropium and their combination in patients with COPD | Pulmonary Pharmacology and Therapeutics | 2004 | 126 |
| 37 | Hyperglycemia in Streptozotocin-Induced Diabetic Rat Increases Infarct Size Associated With Low Levels of Myocardial HO-1 During Ischemia/Reperfusion | Diabetes | 2005 | 125 |
| 38 | Metabolic syndrome and endometrial cancer: a meta-analysis | Endocrine | 2014 | 123 |
| 39 | Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ | Oncogene | 2017 | 123 |
| 40 | Doxorubicin targets multiple players: A new view of an old problem | Pharmacological Research | 2018 | 123 |
| 41 | Novel long‐acting bronchodilators for COPD and asthma | British Journal of Pharmacology | 2008 | 122 |
| 42 | Doxorubicin induces senescence and impairs function of human cardiac progenitor cells | Basic Research in Cardiology | 2013 | 122 |
| 43 | Human Adipose Stem Cells: From Bench to Bedside | Tissue Engineering - Part B: Reviews | 2015 | 121 |
| 44 | Myocardial lipid accumulation in patients with pressure-overloaded heart and metabolic syndrome | Journal of Lipid Research | 2009 | 120 |
| 45 | Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states | Brain | 2015 | 120 |
| 46 | Annexin 1 peptides protect against experimental myocardial ischemia‐reperfusion: analysis of their mechanism of action | FASEB Journal | 2001 | 118 |
| 47 | Production of chondroitin sulfate and chondroitin | Applied Microbiology and Biotechnology | 2010 | 118 |
| 48 | Inhaled ??2-Adrenoceptor Agonists | Drugs | 2005 | 117 |
| 49 | SIRT1 activation attenuates diastolic dysfunction by reducing cardiac fibrosis in a model of anthracycline cardiomyopathy | International Journal of Cardiology | 2016 | 114 |
| 50 | Immunomodulatory effects of Lactobacillus plantarum on human colon cancer cells | International Immunopharmacology | 2009 | 113 |
