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exaly
›
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Department of Physiology
›
top-articles
Department of Physiology
118
(top 1%)
papers
2.9K
(top 1%)
citations
31
(top 1%)
h
-index
51
(top 1%)
g
-index
154
all documents
3.2K
doc citations
1.1K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
PDGFRs are critical for PI3K/Akt activation and negatively regulated by mTOR
Journal of Clinical Investigation
2007
321
2
Regulation of Autophagy by mTOR Signaling Pathway
Advances in Experimental Medicine and Biology
2019
211
3
Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1
Nature Cell Biology
2011
128
4
Human acupuncture points mapped in rats are associated with excitable muscle/skin–nerve complexes with enriched nerve endings
Brain Research
2004
115
5
Three-dimensional bioprinted hepatorganoids prolong survival of mice with liver failure
Gut
2021
108
6
Identification and characterization of selenoprotein K: An antioxidant in cardiomyocytes
FEBS Letters
2006
103
7
S6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage response
EMBO Journal
2010
103
8
Gut stem cell aging is driven by mTORC1 via a p38 MAPK-p53 pathway
Nature Communications
2020
87
9
NMDA receptor activation induces mitochondrial dysfunction, oxidative stress and apoptosis in cultured neonatal rat cardiomyocytes
Physiological Research
2007
84
10
Diurnal oscillations of endogenous H2O2 sustained by p66Shc regulate circadian clocks
Nature Cell Biology
2019
79
11
PDK4 Protein Promotes Tumorigenesis through Activation of cAMP-response Element-binding Protein (CREB)-Ras Homolog Enriched in Brain (RHEB)-mTORC1 Signaling Cascade
Journal of Biological Chemistry
2014
73
12
GH-releasing peptides improve cardiac dysfunction and cachexia and suppress stress-related hormones and cardiomyocyte apoptosis in rats with heart failure
American Journal of Physiology - Heart and Circulatory Physiology
2005
66
13
Effects of ghrelin and synthetic GH secretagogues on the cardiovascular system
Trends in Endocrinology and Metabolism
2006
63
14
Pneumoconiosis: current status and future prospects
Chinese Medical Journal
2021
55
15
Phosphorylation of Raptor by p38β Participates in Arsenite-induced Mammalian Target of Rapamycin Complex 1 (mTORC1) Activation
Journal of Biological Chemistry
2011
54
16
Application of a 3D Bioprinted Hepatocellular Carcinoma Cell Model in Antitumor Drug Research
Frontiers in Oncology
2020
52
17
Hexarelin suppresses high lipid diet and vitamin D3-induced atherosclerosis in the rat
Peptides
2010
51
18
Phosphoglyceric acid mutase-1 contributes to oncogenic mTOR-mediated tumor growth and confers non-small cell lung cancer patients with poor prognosis
Cell Death and Differentiation
2018
51
19
Clock-controlled mir-142-3p can target its activator, Bmal1
BMC Molecular Biology
2012
48
20
SLC7A11/xCT Prevents Cardiac Hypertrophy by Inhibiting Ferroptosis
Cardiovascular Drugs and Therapy
2022
47
21
MTOR inhibition attenuates DNA damage and apoptosis through autophagy-mediated suppression of CREB1
Autophagy
2013
41
22
mTOR/miR-145-regulated exosomal GOLM1 promotes hepatocellular carcinoma through augmented GSK-3β/MMPs
Journal of Genetics and Genomics
2019
41
23
A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea
EMBO Molecular Medicine
2021
41
24
Golgi protein 73 activation of MMP-13 promotes hepatocellular carcinoma cell invasion
Oncotarget
2015
40
25
Multi-omics study of silicosis reveals the potential therapeutic targets PGD
2
and TXA
2
Theranostics
2021
40
26
Antiproliferative effects of melatonin on the growth of rat pituitary prolactin-secreting tumor cells in vitro
Journal of Pineal Research
2007
39
27
Memory-related changes of nitric oxide synthase activity and nitrite level in rat brain
NeuroReport
1997
38
28
Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated Tumorigenesis
Journal of Biological Chemistry
2015
37
29
The acute toxic effects of silver nanoparticles on myocardial transmembrane potential,
I
Na
and
I
K1
channels and heart rhythm in mice
Nanotoxicology
2017
37
30
mTOR promotes pituitary tumor development through activation of PTTG1
Oncogene
2017
36
31
Efficacy of combined inhibition of mTOR and ERK/MAPK pathways in treating a tuberous sclerosis complex cell model
Journal of Genetics and Genomics
2009
34
32
Spinal cord injury triggers sensitization of wide dynamic range dorsal horn neurons in segments rostral to the injury
Brain Research
2005
33
33
Degeneration and energy shortage in the suprachiasmatic nucleus underlies the circadian rhythm disturbance in ApoE−/− mice: implications for Alzheimer’s disease
Scientific Reports
2016
32
34
CLOCK/BMAL1 regulates human nocturnin transcription through binding to the E-box of nocturnin promoter
Molecular and Cellular Biochemistry
2008
31
35
A novel role of microRNA 17-5p in the modulation of circadian rhythm
Scientific Reports
2016
31
36
<p>The acute toxic effects of platinum nanoparticles on ion channels, transmembrane potentials of cardiomyocytes in vitro and heart rhythm in vivo in mice</p>
International Journal of Nanomedicine
2019
28
37
Early demyelination of primary A-fibers induces a rapid-onset of neuropathic pain in rat
Neuroscience
2012
27
38
A microRNA-1280/JAG2 network comprises a novel biological target in high-risk medulloblastoma
Oncotarget
2015
24
39
ON THE INVERSE CHANGE BETWEEN THE CONCENTRATION OF GLUCOSE AND CHLORIDE IN THE BLOOD
American Journal of Physiology
1926
23
40
Huaier aqueous extract sensitizes cells to rapamycin and cisplatin through activating mTOR signaling
Journal of Ethnopharmacology
2016
21
41
Analysis of genetic and clinical characteristics of a Chinese Kallmann syndrome cohort with ANOS1 mutations
European Journal of Endocrinology
2017
21
42
Inhibitory effects of melatonin on the growth of pituitary prolactin-secreting tumor in rats
Journal of Pineal Research
2006
20
43
Activation of AMPA receptor promotes TNF-α release via the ROS-cSrc-NFκB signaling cascade in RAW264.7 macrophages
Biochemical and Biophysical Research Communications
2015
19
44
Deficient TSC1/TSC2-complex suppression of SOX9-osteopontin-AKT signalling cascade constrains tumour growth in tuberous sclerosis complex
Human Molecular Genetics
2017
19
45
The three branches of the unfolded protein response exhibit differential significance in breast cancer growth and stemness
Experimental Cell Research
2018
19
46
p97/VCP is highly expressed in the stem-like cells of breast cancer and controls cancer stemness partly through the unfolded protein response
Cell Death and Disease
2021
19
47
Comparative Transcriptome Analyses Reveal a Transcriptional Landscape of Human Silicosis Lungs and Provide Potential Strategies for Silicosis Treatment
Frontiers in Genetics
2021
19
48
Oxidative status in the macula densa modulates tubuloglomerular feedback responsiveness in Angiotensin
II
‐induced hypertension
Acta Physiologica
2015
18
49
Huaier aqueous extract inhibits proliferation and metastasis of tuberous sclerosis complex cell models through downregulation of JAK2/STAT3 and MAPK signaling pathways
Oncology Reports
2016
18
50
Inhibitory effect and mechanism of acarbose combined with gymnemic acid on maltose absorption in rat intestine
World Journal of Gastroenterology
2001
18
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